Hydrolysis Mechanism of the Linkers by Matrix Metalloproteinase-9 Using QM/MM Calculations

De-shielding of activatable cell-penetrating peptides: recognizing and releasing in activation process

(2021) Binbin Chen et al.   RESEARCH ON CHEMICAL INTERMEDIATES

Dominative role of MMP-14 over MMP-15 in human urinary bladder carcinoma on the basis of its enhanced specific activity

(2020) Jacek Kudelski et al.   MEDICINE

Tumour targetable and microenvironment-responsive nanoparticles simultaneously disrupt the PD-1/PD-L1 pathway and MAPK/ERK/JNK pathway for efficient treatment of colorectal cancer

(2020) Yan Li et al.   JOURNAL OF DRUG TARGETING

Hydroxamate-Based Selective Macrophage Elastase (MMP-12) Inhibitors and Radiotracers for Molecular Imaging

(2020) Kiran Gona et al.   JOURNAL OF MEDICINAL CHEMISTRY

Binding, selectivity and sequence recognition of matrix metalloproteinase-2 to oligopeptides

(2019) Cai Yao et al.   JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS

Mechanisms of Action of Novel Drugs Targeting Angiogenesis-Promoting Matrix Metalloproteinases

(2019) Gregg B. Fields   Frontiers in Immunology

Multi‐Stimuli‐Responsive Polymeric Prodrug for Enhanced Cancer Treatment

(2019) Yue Wang et al.   MACROMOLECULAR BIOSCIENCE

Identification of selective MMP-9 inhibitors through multiple e-pharmacophore, ligand-based pharmacophore, molecular docking, and density functional theory approaches

(2018) Srabanti Jana et al.   JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS

Cell Penetrating Peptides as Molecular Carriers for Anti-Cancer Agents

(2018) Antonella Borrelli et al.   MOLECULES

Direct loading of CTL epitopes onto MHC class I complexes on dendritic cell surface in vivo

(2018) Peng Wang et al.   BIOMATERIALS

Cell penetrating peptides: A concise review with emphasis on biomedical applications

(2018) Hossein Derakhshankhah et al.   BIOMEDICINE & PHARMACOTHERAPY

Enhancing siRNA-based cancer therapy using a new pH-responsive activatable cell-penetrating peptide-modified liposomal system

(2017) Bai Xiang et al.   International Journal of Nanomedicine

Distinct Protein Hydration Water Species Defined by Spatially Resolved Spectra of Intermolecular Vibrations

(2017) Viren Pattni et al.   JOURNAL OF PHYSICAL CHEMISTRY B

Solvent water interactions within the active site of the membrane type I matrix metalloproteinase

(2017) Elena Decaneto et al.   PHYSICAL CHEMISTRY CHEMICAL PHYSICS

Sugar-Based Arylsulfonamide Carboxylates as Selective and Water-Soluble Matrix Metalloproteinase-12 Inhibitors

(2016) Elisa Nuti et al.   ChemMedChem

Reaction mechanism of matrix metalloproteinases with a catalytically active zinc ion studied by the QM(DFTB)/MM simulations

(2016) Tatiana Vasilevskaya et al.   MENDELEEV COMMUNICATIONS

Pressure and Temperature Effects on the Activity and Structure of the Catalytic Domain of Human MT1-MMP

(2015) Elena Decaneto et al.   BIOPHYSICAL JOURNAL

Mixed Quantum Mechanical/Molecular Mechanical Molecular Dynamics Simulations of Biological Systems in Ground and Electronically Excited States

(2015) Elizabeth Brunk et al.   CHEMICAL REVIEWS

Mechanism of proteolysis in matrix metalloproteinase-2 revealed by QM/MM modeling

(2015) Tatiana Vasilevskaya et al.   JOURNAL OF COMPUTATIONAL CHEMISTRY

Unravelling the reaction mechanism of matrix metalloproteinase 3 using QM/MM calculations

(2015) Gustavo Troiano Feliciano et al.   JOURNAL OF MOLECULAR STRUCTURE

ZDOCK server: interactive docking prediction of protein-protein complexes and symmetric multimers

(2014) B. G. Pierce et al.   BIOINFORMATICS

Chemotherapeutic drug delivery to cancer cells using a combination of folate targeting and tumor microenvironment-sensitive polypeptides

(2013) Wei Gao et al.   BIOMATERIALS

Matrix metalloproteinase and its drug targets therapy in solid and hematological malignancies: An overview

(2013) Ajay Kumar Chaudhary et al.   MUTATION RESEARCH-REVIEWS IN MUTATION RESEARCH

Tumor Targeting of MMP-2/9 Activatable Cell-Penetrating Imaging Probes Is Caused by Tumor-Independent Activation

(2011) S. M. J. van Duijnhoven et al.   JOURNAL OF NUCLEAR MEDICINE

Matrix Metalloproteinases: Regulators of the Tumor Microenvironment

(2010) Kai Kessenbrock et al.   CELL

Structural Survey of Zinc-Containing Proteins and Development of the Zinc AMBER Force Field (ZAFF)

(2010) Martin B. Peters et al.   Journal of Chemical Theory and Computation

QM/MM Methods for Biomolecular Systems

(2009) Hans Martin Senn et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

DL-FIND: An Open-Source Geometry Optimizer for Atomistic Simulations†

(2009) Johannes Kästner et al.   JOURNAL OF PHYSICAL CHEMISTRY A

Peptide Hydrolysis Catalyzed by Matrix Metalloproteinase 2: A Computational Study

(2008) Dr. Natalia Díaz et al.   JOURNAL OF PHYSICAL CHEMISTRY B