The tumor-suppressive long noncoding RNA DRAIC inhibits protein translation and induces autophagy by activating AMPK

Long Noncoding RNA DRAIC Inhibits Prostate Cancer Progression by Interacting with IKK to Inhibit NF-κB Activation

(2020) Shekhar Saha et al.   CANCER RESEARCH

Glioblastoma in Adults: A Society for Neuro-Oncology (SNO) and European Society of Neuro-Oncology (EANO) Consensus Review on Current Management and Future Directions

(2020) Patrick Y Wen et al.   NEURO-ONCOLOGY

A cytoskeleton regulator AVIL drives tumorigenesis in glioblastoma

(2020) Zhongqiu Xie et al.   Nature Communications

Gene regulation by long non-coding RNAs and its biological functions

(2020) Luisa Statello et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

A high-throughput screen identifies the long non-coding RNA DRAIC as a regulator of autophagy

(2019) Imke Tiessen et al.   ONCOGENE

Regorafenib induces lethal autophagy arrest by stabilizing PSAT1 in glioblastoma

(2019) Jingwen Jiang et al.   Autophagy

α-Ketoglutarate-Activated NF-κB Signaling Promotes Compensatory Glucose Uptake and Brain Tumor Development

(2019) Xiongjun Wang et al.   MOLECULAR CELL

Lnc-THOR silencing inhibits human glioma cell survival by activating MAGEA6-AMPK signaling

(2019) Jun Xue et al.   Cell Death & Disease

Emerging roles of long non-coding RNA in cancer

(2018) Anna Sanchez Calle et al.   CANCER SCIENCE

STAT3-induced lncRNA HAGLROS overexpression contributes to the malignant progression of gastric cancer cells via mTOR signal-mediated inhibition of autophagy

(2018) Jin-Fei Chen et al.   Molecular Cancer

lncRNA DLEU1 contributes to tumorigenesis and development of endometrial carcinoma by targeting mTOR

(2018) Yuping Du et al.   MOLECULAR CARCINOGENESIS

Targeting autophagy for combating chemoresistance and radioresistance in glioblastoma

(2018) Matthew A. Taylor et al.   APOPTOSIS

Mechanisms of invasion and motility of high-grade gliomas in the brain

(2018) Devin B. Mair et al.   MOLECULAR BIOLOGY OF THE CELL

Inhibition of mTORC1 by lncRNA H19 via disrupting 4E-BP1/Raptor interaction in pituitary tumours

(2018) Ze Rui Wu et al.   Nature Communications

New insights into autophagosome–lysosome fusion

(2017) Shuhei Nakamura et al.   JOURNAL OF CELL SCIENCE

The functions and unique features of long intergenic non-coding RNA

(2017) Julia D. Ransohoff et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Long Noncoding RNA MALAT1 Promotes Hepatocellular Carcinoma Development by SRSF1 Upregulation and mTOR Activation

(2016) Pushkar Malakar et al.   CANCER RESEARCH

p62- and ubiquitin-dependent stress-induced autophagy of the mammalian 26S proteasome

(2016) Victoria Cohen-Kaplan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A positive feedback loop involving EGFR/Akt/mTORC1 and IKK/NF-κB regulates head and neck squamous cell carcinoma proliferation

(2016) Zhipeng Li et al.   Oncotarget

mTOR: a pharmacologic target for autophagy regulation

(2015) Young Chul Kim et al.   JOURNAL OF CLINICAL INVESTIGATION

The lncRNA DRAIC/PCAT29 Locus Constitutes a Tumor-Suppressive Nexus

(2015) K. Sakurai et al.   MOLECULAR CANCER RESEARCH

Discovery, Annotation, and Functional Analysis of Long Noncoding RNAs Controlling Cell-Cycle Gene Expression and Proliferation in Breast Cancer Cells

(2015) Miao Sun et al.   MOLECULAR CELL

Correlation of long non-coding RNA expression with metastasis, drug resistance and clinical outcome in cancer

(2015) Ehsan Malek et al.   Oncotarget

Long Noncoding RNAs: Emerging Stars in Gene Regulation, Epigenetics and Human Disease

(2014) Arunoday Bhan et al.   ChemMedChem

Autophagy Inhibition Augments the Anticancer Effects of Epirubicin Treatment in Anthracycline-Sensitive and -Resistant Triple-Negative Breast Cancer

(2014) S. Chittaranjan et al.   CLINICAL CANCER RESEARCH

AMPK: Regulating Energy Balance at the Cellular and Whole Body Levels

(2014) D. Grahame Hardie et al.   PHYSIOLOGY

Review Glioblastoma multiforme – an overview

(2014) Kaja Urbańska et al.   Wspolczesna Onkologia-Contemporary Oncology

NF- B, an Active Player in Human Cancers

(2014) Y. Xia et al.   Cancer Immunology Research

The mTOR Signalling Pathway in Human Cancer

(2012) Helena Pópulo et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Posttranscriptional Gene Regulation by Long Noncoding RNA

(2012) Je-Hyun Yoon et al.   JOURNAL OF MOLECULAR BIOLOGY

The hallmarks of cancer

(2012) Tony Gutschner et al.   RNA Biology

The autophagy initiating kinase ULK1 is regulated via opposing phosphorylation by AMPK and mTOR

(2011) Dan Egan et al.   Autophagy

Cross-Talk between AMPK and mTOR in Regulating Energy Balance

(2011) Jia Xu et al.   CRITICAL REVIEWS IN FOOD SCIENCE AND NUTRITION

AMPK promotes skeletal muscle autophagy through activation of forkhead FoxO3a and interaction with Ulk1

(2011) Anthony MJ Sanchez et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Role of AMPK-mTOR-Ulk1/2 in the Regulation of Autophagy: Cross Talk, Shortcuts, and Feedbacks

(2011) S. Alers et al.   MOLECULAR AND CELLULAR BIOLOGY

Structure of mammalian AMPK and its regulation by ADP

(2011) Bing Xiao et al.   NATURE

AMPK and mTOR regulate autophagy through direct phosphorylation of Ulk1

(2011) Joungmok Kim et al.   NATURE CELL BIOLOGY

A phase II trial of erlotinib in patients with recurrent malignant gliomas and nonprogressive glioblastoma multiforme postradiation therapy

(2011) J. J. Raizer et al.   NEURO-ONCOLOGY

Long noncoding RNA in genome regulation

(2011) Tiffany Hung et al.   RNA Biology

mTOR regulation of autophagy

(2010) Chang Hwa Jung et al.   FEBS LETTERS

Long non-coding RNA HOTAIR reprograms chromatin state to promote cancer metastasis

(2010) Rajnish A. Gupta et al.   NATURE

Phosphorylation of ULK1 (hATG1) by AMP-Activated Protein Kinase Connects Energy Sensing to Mitophagy

(2010) D. F. Egan et al.   SCIENCE

LKB1 and AMP-activated protein kinase control of mTOR signalling and growth

(2009) R. J. Shaw   Acta Physiologica

Glioblastoma multiforme: a review of where we have been and where we are going

(2009) Cory Adamson et al.   EXPERT OPINION ON INVESTIGATIONAL DRUGS

Akt-dependent regulation of NF- B is controlled by mTOR and Raptor in association with IKK

(2008) H. C. Dan et al.   GENES & DEVELOPMENT

AMPK Phosphorylation of Raptor Mediates a Metabolic Checkpoint

(2008) Dana M. Gwinn et al.   MOLECULAR CELL