Progesterone receptor membrane component 1 (PGRMC1) binds and stabilizes cytochromes P450 through a heme-independent mechanism

A 127 kb truncating deletion of PGRMC1 is a novel cause of X-linked isolated paediatric cataract

(2021) Johanna L. Jones et al.   EUROPEAN JOURNAL OF HUMAN GENETICS

Novel nonclassic progesterone receptor PGRMC1 pulldown-precipitated proteins reveal a key role during human decidualization

(2020) Stefania Salsano et al.   FERTILITY AND STERILITY

Induction via Functional Protein Stabilization of Hepatic Cytochromes P450 upon gp78/Autocrine Motility Factor Receptor (AMFR) Ubiquitin E3-ligase Genetic Ablation in Mice: Therapeutic and Toxicological Relevance.

(2019) Doyoung Kwon et al.   MOLECULAR PHARMACOLOGY

PGRMC2 is an intracellular haem chaperone critical for adipocyte function

(2019) Andrea Galmozzi et al.   NATURE

PANTHER version 14: more genomes, a new PANTHER GO-slim and improvements in enrichment analysis tools

(2018) Huaiyu Mi et al.   NUCLEIC ACIDS RESEARCH

The PRIDE database and related tools and resources in 2019: improving support for quantification data

(2018) Yasset Perez-Riverol et al.   NUCLEIC ACIDS RESEARCH

Advances in the Understanding of Protein-Protein Interactions in Drug Metabolizing Enzymes through the Use of Biophysical Techniques

(2017) Jed N. Lampe   Frontiers in Pharmacology

A Novel Role for Progesterone Receptor Membrane Component 1 (PGRMC1): A Partner and Regulator of Ferrochelatase

(2016) Robert B. Piel et al.   BIOCHEMISTRY

Progesterone receptor membrane component 1 promotes survival of human breast cancer cells and the growth of xenograft tumors

(2016) Nicole C. Clark et al.   CANCER BIOLOGY & THERAPY

Hepatic cytochromes P450: structural degrons and barcodes, posttranslational modifications and cellular adapters in the ERAD-endgame

(2016) Sung-Mi Kim et al.   DRUG METABOLISM REVIEWS

Conditional Ablation of Progesterone Receptor Membrane Component 1 Results in Subfertility in the Female and Development of Endometrial Cysts

(2016) Melissa L. McCallum et al.   ENDOCRINOLOGY

Acetaminophen from liver to brain: New insights into drug pharmacological action and toxicity

(2016) Carolina I. Ghanem et al.   PHARMACOLOGICAL RESEARCH

Haem-dependent dimerization of PGRMC1/Sigma-2 receptor facilitates cancer proliferation and chemoresistance

(2016) Yasuaki Kabe et al.   Nature Communications

Regulation of Human Cytochrome P4501A1 (hCYP1A1): A Plausible Target for Chemoprevention?

(2016) Rebeca Santes-Palacios et al.   Biomed Research International

Spectroscopic and Mutagenesis Studies of Human PGRMC1

(2015) Daniel Kaluka et al.   BIOCHEMISTRY

Progesterone receptor membrane component-1 regulates hepcidin biosynthesis

(2015) Xiang Li et al.   JOURNAL OF CLINICAL INVESTIGATION

limma powers differential expression analyses for RNA-sequencing and microarray studies

(2015) Matthew E. Ritchie et al.   NUCLEIC ACIDS RESEARCH

Tissue-based map of the human proteome

(2015) M. Uhlen et al.   SCIENCE

Dose-Response Analysis Using R

(2015) Christian Ritz et al.   PLoS One

Progesterone Receptor Membrane Component-1 (PGRMC1) and PGRMC-2 Interact to Suppress Entry into the Cell Cycle in Spontaneously Immortalized Rat Granulosa Cells1

(2014) John J. Peluso et al.   BIOLOGY OF REPRODUCTION

Cell-Type-Resolved Quantitative Proteomics of Murine Liver

(2014) S. Babak Azimifar et al.   Cell Metabolism

Catalytically Relevant Electrostatic Interactions of Cytochrome P450c17 (CYP17A1) and Cytochromeb5

(2014) Hwei-Ming Peng et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Human Cytochrome P450 17A1 Conformational Selection

(2014) D. Fernando Estrada et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Progesterone Receptor Membrane Component 1 Is a Functional Part of the Glucagon-like Peptide-1 (GLP-1) Receptor Complex in Pancreatic β Cells

(2014) Ming Zhang et al.   MOLECULAR & CELLULAR PROTEOMICS

Progesterone receptor membrane component 1/Sigma-2 receptor associates with MAP1LC3B and promotes autophagy

(2013) Shakeel UR Mir et al.   Autophagy

Substrate-modulated Cytochrome P450 17A1 and Cytochromeb5Interactions Revealed by NMR

(2013) D. Fernando Estrada et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Quantitative accuracy in mass spectrometry based proteomics of complex samples: The impact of labeling and precursor interference

(2013) AnnSofi Sandberg et al.   Journal of Proteomics

Genome engineering using the CRISPR-Cas9 system

(2013) F Ann Ran et al.   Nature Protocols

One ring to rule them all: Trafficking of heme and heme synthesis intermediates in the metazoans

(2012) Iqbal Hamza et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Statistical Inference from Multiple iTRAQ Experiments without Using Common Reference Standards

(2012) Shelley M. Herbrich et al.   JOURNAL OF PROTEOME RESEARCH

Mouse Knockout of the Cholesterogenic Cytochrome P450 Lanosterol 14α-Demethylase (Cyp51) Resembles Antley-Bixler Syndrome

(2011) Rok Keber et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Pgrmc1 (Progesterone Receptor Membrane Component 1) Associates with Epidermal Growth Factor Receptor and Regulates Erlotinib Sensitivity

(2010) Ikhlas S. Ahmed et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Progesterone Receptor Membrane Component 1 (Pgrmc1): A Heme-1 Domain Protein That Promotes Tumorigenesis and Is Inhibited by a Small Molecule

(2010) I. S. Ahmed et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

Proliferative and Nonproliferative Lesions of the Rat and Mouse Hepatobiliary System

(2010) Bob Thoolen et al.   TOXICOLOGIC PATHOLOGY

Structure, function, regulation and polymorphism and the clinical significance of human cytochrome P450 1A2

(2009) Shu-Feng Zhou et al.   DRUG METABOLISM REVIEWS

Progesterone Receptor Membrane Component-1 Regulates the Development and Cisplatin Sensitivity of Human Ovarian Tumors in Athymic Nude Mice

(2009) John J. Peluso et al.   ENDOCRINOLOGY

Regulation of Ovarian Cancer Cell Viability and Sensitivity to Cisplatin by Progesterone Receptor Membrane Component-1

(2008) John J. Peluso et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM