4.3 Article

The reliability and validity of triceps surae muscle volume assessment using freehand three-dimensional ultrasound in typically developing infants

期刊

JOURNAL OF ANATOMY
卷 240, 期 3, 页码 567-578

出版社

WILEY
DOI: 10.1111/joa.13565

关键词

child; muscle volume; reliability; statistical shape modelling; ultrasound; validity

资金

  1. National Health and Medical Research Council
  2. Auckland Medical Research Foundation
  3. Auckland Academic Health Alliance

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This study confirmed the reliability of using freehand 3D ultrasound to measure triceps surae muscle volume in typically developing infants, with acceptable levels of agreement compared to MRI. Despite overestimating the volume of the medial and lateral gastrocnemius muscles, and underestimating the soleus muscle, freehand 3D ultrasound is still a useful tool for assessing changes in muscle volume in infants.
This study assessed the intra-acquirer, intra- and inter-processor reliability, and validity of the in vivo assessment of the medial gastrocnemius (MG), lateral gastrocnemius (LG) and soleus (SOL) muscle volumes using freehand 3D ultrasound (3DUS) in typically developing infants. Reliability assessments of freehand 3DUS were undertaken in infants across three ages groups: three, six and twelve months of age, with validity testing completed against magnetic resonance imaging (MRI) in infants at 3 months of age. Freehand 3DUS scanning was carried out by a single acquirer, with two independent processors manually segmenting images to render volumes. MRI images were segmented independently by a separate processor, with the volumes compared to those obtained via freehand 3DUS. Reliability was assessed using intraclass correlation (ICC), coefficient of variance (CV) and minimal detectable change (MDC) across each assessment time point. Validity was assessed using the limits of agreement. ICCs for intra-acquirer reliability of the acquisition process for freehand 3DUS ranged from 0.91 to 0.99 across all muscles. ICCs for intra-processor and inter-processor reliability for the segmentation process of freehand 3DUS ranged from 0.80 to 0.98 across all muscles. Acceptable levels of agreement between muscle volume obtained by freehand 3DUS and MRI were found for all muscles; however, freehand 3DUS overestimated muscle volume of MG and LG and underestimate the SOL compared with MRI, with average absolute differences of MG = 0.3 ml, LG = 0.3 ml and Sol = 1.2 ml. Freehand 3DUS is a reliable method for measuring in vivo triceps surae muscle volume in typically developing infants. We conclude that freehand 3DUS is a useful tool to assess changes in muscle volume in response to growth and interventions in infants.

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