Expression and Functional Contribution of Different Organic Cation Transporters to the Cellular Uptake of Doxorubicin into Human Breast Cancer and Cardiac Tissue
出版年份 2021 全文链接
标题
Expression and Functional Contribution of Different Organic Cation Transporters to the Cellular Uptake of Doxorubicin into Human Breast Cancer and Cardiac Tissue
作者
关键词
-
出版物
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
Volume 23, Issue 1, Pages 255
出版商
MDPI AG
发表日期
2021-12-28
DOI
10.3390/ijms23010255
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Targeting OCT3 attenuates doxorubicin-induced cardiac injury
- (2021) Kevin M. Huang et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- IVIVE of Transporter-Mediated Renal Clearance: Relative Expression Factor (REF) vs Relative Activity Factor (RAF) Approach
- (2021) Aditya R. Kumar et al. DRUG METABOLISM AND DISPOSITION
- Organic Anion Transporting Polypeptides: Emerging Roles in Cancer Pharmacology
- (2019) Rachael R. Schulte et al. MOLECULAR PHARMACOLOGY
- Organic Cation Transporters in Health and Disease
- (2019) Hermann Koepsell PHARMACOLOGICAL REVIEWS
- Disease-Associated Changes in Drug Transporters May Impact the Pharmacokinetics and/or Toxicity of Drugs: A White Paper From the International Transporter Consortium
- (2018) Raymond Evers et al. CLINICAL PHARMACOLOGY & THERAPEUTICS
- Molecular mechanism of doxorubicin-induced cardiomyopathy – An update
- (2018) Kaviyarasi Renu et al. EUROPEAN JOURNAL OF PHARMACOLOGY
- Drug transporters and anthracycline-induced cardiotoxicity
- (2018) Kevin M Huang et al. PHARMACOGENOMICS
- Effects of frequently used pharmaceutical excipients on the organic cation transporters 1–3 and peptide transporters 1/2 stably expressed in MDCKII cells
- (2017) Marcus Otter et al. EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS
- Epigenetic regulation of drug transporter expression in human tissues
- (2016) Takeshi Hirota et al. Expert Opinion on Drug Metabolism & Toxicology
- Cation-selective transporters are critical to the AMPK-mediated antiproliferative effects of metformin in human breast cancer cells
- (2016) Hao Cai et al. INTERNATIONAL JOURNAL OF CANCER
- The human organic cation transporter OCT1 mediates high affinity uptake of the anticancer drug daunorubicin
- (2016) Emil Andreev et al. Scientific Reports
- Genetic Polymorphisms and Function of the Organic Anion-Transporting Polypeptide 1A2 and Its Clinical Relevance in Drug Disposition
- (2015) Yinhui Zhou et al. PHARMACOLOGY
- Whole-exome analysis reveals novel somatic genomic alterations associated with outcome in immunochemotherapy-treated diffuse large B-cell lymphoma
- (2015) A J Novak et al. Blood Cancer Journal
- Complementation of the Yeast Model System Reveals that Caenorhabditis elegans OCT-1 Is a Functional Transporter of Anthracyclines
- (2015) Nicolas Brosseau et al. PLoS One
- Expression of organic anion-transporting polypeptide 1A2 and organic cation transporter 6 as a predictor of pathologic response to neoadjuvant chemotherapy in triple negative breast cancer
- (2014) Yumi Hashimoto et al. BREAST CANCER RESEARCH AND TREATMENT
- In vivodisposition of doxorubicin is affected by mouse Oatp1a/1b and human OATP1A/1B transporters
- (2014) Selvi Durmus et al. INTERNATIONAL JOURNAL OF CANCER
- Expression of Drug Transporters and Drug Metabolizing Enzymes in the Bladder Urothelium in Man and Affinity of the Bladder Spasmolytic Trospium Chloride to Transporters Likely Involved in Its Pharmacokinetics
- (2014) Maria Bexten et al. MOLECULAR PHARMACEUTICS
- LC–MS/MS-based quantification of clinically relevant intestinal uptake and efflux transporter proteins
- (2013) C. Gröer et al. JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS
- Increased Expression of P-Glycoprotein and Doxorubicin Chemoresistance of Metastatic Breast Cancer Is Regulated by miR-298
- (2012) Lili Bao et al. AMERICAN JOURNAL OF PATHOLOGY
- SLC22A5/OCTN2 expression in breast cancer is induced by estrogen via a novel intronic estrogen-response element (ERE)
- (2012) Chunyu Wang et al. BREAST CANCER RESEARCH AND TREATMENT
- Doxorubicin-induced cardiomyopathy: From molecular mechanisms to therapeutic strategies
- (2012) Yanti Octavia et al. JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY
- Identification of the molecular basis of doxorubicin-induced cardiotoxicity
- (2012) Sui Zhang et al. NATURE MEDICINE
- Selective Regulation of Cardiac Organic Cation Transporter Novel Type 2 (OCTN2) in Dilated Cardiomyopathy
- (2011) Markus Grube et al. AMERICAN JOURNAL OF PATHOLOGY
- The Expression and Function of Organic Anion Transporting Polypeptides in Normal Tissues and in Cancer
- (2011) Amanda Obaidat et al. Annual Review of Pharmacology and Toxicology
- Acute Exposure to Doxorubicin Results in Increased Cardiac P-glycoprotein Expression
- (2011) Thomas Budde et al. JOURNAL OF PHARMACEUTICAL SCIENCES
- Influence of the flavonoids apigenin, kaempferol, and quercetin on the function of organic anion transporting polypeptides 1A2 and 2B1
- (2010) Kathrin Mandery et al. BIOCHEMICAL PHARMACOLOGY
- P-glycoprotein inhibition using valspodar (PSC-833) does not improve outcomes for patients younger than age 60 years with newly diagnosed acute myeloid leukemia: Cancer and Leukemia Group B study 19808
- (2010) J. E. Kolitz et al. BLOOD
- Altered expression of organic anion transporter polypeptide (OATP) genes in human breast carcinoma
- (2010) Katrin Wlcek et al. CANCER BIOLOGY & THERAPY
- Doxorubicin pathways
- (2010) Caroline F. Thorn et al. Pharmacogenetics and Genomics
- Impact of OATP transporters on pharmacokinetics
- (2009) A Kalliokoski et al. BRITISH JOURNAL OF PHARMACOLOGY
- Doxorubicin Cardiomyopathy
- (2009) Kanu Chatterjee et al. CARDIOLOGY
- Doxorubicin: The Good, the Bad and the Ugly Effect
- (2009) Cristina Carvalho et al. CURRENT MEDICINAL CHEMISTRY
- The Organic Cation Transporter, OCTN1, Expressed in the Human Heart, Potentiates Antagonism of the HERG Potassium Channel
- (2009) Brian F McBride et al. JOURNAL OF CARDIOVASCULAR PHARMACOLOGY
- Interplay between the Nuclear Receptor Pregnane X Receptor and the Uptake Transporter Organic Anion Transporter Polypeptide 1A2 Selectively Enhances Estrogen Effects in Breast Cancer
- (2008) H. E. Meyer zu Schwabedissen et al. CANCER RESEARCH
- Profiling SLCO and SLC22 genes in the NCI-60 cancer cell lines to identify drug uptake transporters
- (2008) M. Okabe et al. MOLECULAR CANCER THERAPEUTICS
- ATP-binding cassette transporters in human heart failure
- (2008) Thomas F. Solbach et al. NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY
Discover Peeref hubs
Discuss science. Find collaborators. Network.
Join a conversationCreate your own webinar
Interested in hosting your own webinar? Check the schedule and propose your idea to the Peeref Content Team.
Create Now