标题
Cytochrome P450 Enzymes and Drug Metabolism in Humans
作者
关键词
-
出版物
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
Volume 22, Issue 23, Pages 12808
出版商
MDPI AG
发表日期
2021-12-01
DOI
10.3390/ijms222312808
参考文献
相关参考文献
注意：仅列出部分参考文献，下载原文获取全部文献信息。- An emerging potential of metabolomics in multiple sclerosis: a comprehensive overview
- (2021) Insha Zahoor et al. CELLULAR AND MOLECULAR LIFE SCIENCES
- Intratumoural Cytochrome P450 Expression in Breast Cancer: Impact on Standard of Care Treatment and New Efforts to Develop Tumour-Selective Therapies
- (2021) Smarakan Sneha et al. Biomedicines
- Metabolism and interactions of Ivermectin with human cytochrome P450 enzymes and drug transporters, possible adverse and toxic effects
- (2021) Slobodan P. Rendic ARCHIVES OF TOXICOLOGY
- The Role of Pharmacogenetics in Smoking
- (2021) Ahmed El‐Boraie et al. CLINICAL PHARMACOLOGY & THERAPEUTICS
- Enantioselectivity in Drug Pharmacokinetics and Toxicity: Pharmacological Relevance and Analytical Methods
- (2021) Maria Miguel Coelho et al. MOLECULES
- Deregulation of signaling pathways controlling cell survival and proliferation in cancer cells alters induction of cytochrome P450 family 1 enzymes
- (2021) Martin Krkoška et al. TOXICOLOGY
- Effect of Environmental Exposure and Pharmacogenomics on Drug Metabolism
- (2020) Basu Dev Banerjee et al. CURRENT DRUG METABOLISM
- Carvedilol serves as a novel CYP1B1 inhibitor, a systematic drug repurposing approach through structure-based virtual screening and experimental verification
- (2020) Ying Wang et al. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
- Clinical Pharmacogenetics Implementation Consortium (CPIC) Guideline for CYP2C19 and Proton Pump Inhibitor Dosing
- (2020) John J. Lima et al. CLINICAL PHARMACOLOGY & THERAPEUTICS
- Clinical Pharmacogenetics Implementation Consortium (CPIC) Guideline for CYP2C9 and HLA‐B Genotypes and Phenytoin Dosing: 2020 Update
- (2020) Jason H. Karnes et al. CLINICAL PHARMACOLOGY & THERAPEUTICS
- Digital Microfluidics-Enabled Analysis of Individual Variation in Liver Cytochrome P450 Activity
- (2020) Gowtham Sathyanarayanan et al. ANALYTICAL CHEMISTRY
- Model‐based Quantification of Impact of Genetic Polymorphisms and Co‐Medications on Pharmacokinetics of Tamoxifen and Six Metabolites in Breast Cancer
- (2020) Alicja Puszkiel et al. CLINICAL PHARMACOLOGY & THERAPEUTICS
- Regulation of cytochrome P450 enzyme activity and expression by nitric oxide in the context of inflammatory disease
- (2020) Edward T. Morgan et al. DRUG METABOLISM REVIEWS
- Potential role of drug metabolizing enzymes in chemotherapy-induced gastrointestinal toxicity and hepatotoxicity
- (2020) Gabriel Tao et al. Expert Opinion on Drug Metabolism & Toxicology
- Expression of cytochrome P450 isozyme transcripts and activities in human livers
- (2020) Jie Liu et al. XENOBIOTICA
- Cytochrome P450 Metabolism of Polyunsaturated Fatty Acids and Neurodegeneration
- (2020) Morteza Sarparast et al. Nutrients
- Pharmacogenetics of antipsychotics: Clinical utility and implementation
- (2020) Maria J. Arranz et al. BEHAVIOURAL BRAIN RESEARCH
- Physiologically Based Pharmacokinetic Models for Prediction of Complex CYP2C8 and OATP1B1 (SLCO1B1) Drug–Drug–Gene Interactions: A Modeling Network of Gemfibrozil, Repaglinide, Pioglitazone, Rifampicin, Clarithromycin and Itraconazole
- (2019) Denise Türk et al. CLINICAL PHARMACOKINETICS
- Drug metabolizing enzymes-associated chemo resistance and strategies to overcome it
- (2019) Himanshu Verma et al. DRUG METABOLISM REVIEWS
- Standardizing CYP 2D6 Genotype to Phenotype Translation: Consensus Recommendations from the Clinical Pharmacogenetics Implementation Consortium and Dutch Pharmacogenetics Working Group
- (2019) Kelly E. Caudle et al. CTS-Clinical and Translational Science
- Drug–drug–gene interactions and adverse drug reactions
- (2019) Mustafa Adnan Malki et al. PHARMACOGENOMICS JOURNAL
- Complex Drug–Drug–Gene–Disease Interactions Involving Cytochromes P450: Systematic Review of Published Case Reports and Clinical Perspectives
- (2018) Flavia Storelli et al. CLINICAL PHARMACOKINETICS
- Cytochrome P450 Structure, Function and Clinical Significance: A Review
- (2018) Palrasu Manikandan et al. CURRENT DRUG TARGETS
- Cytochrome P450 in the central nervous system as a therapeutic target in neurodegenerative diseases
- (2018) Cynthia Navarro-Mabarak et al. DRUG METABOLISM REVIEWS
- Food-drug interactions precipitated by fruit juices other than grapefruit juice: An update review
- (2018) Meng Chen et al. JOURNAL OF FOOD AND DRUG ANALYSIS
- CYP-mediated drug metabolism in the brain impacts drug response
- (2018) Douglas M. McMillan et al. PHARMACOLOGY & THERAPEUTICS
- Targeting cytochrome P450-dependent cancer cell mitochondria: cancer associated CYPs and where to find them
- (2018) Zhijun Guo et al. CANCER AND METASTASIS REVIEWS
- Inhibitors of cytochrome P450 (CYP) 1B1
- (2017) Raphaël Dutour et al. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
- A new opportunity for nanomedicines: Micellar cytochrome P450 inhibitors to improve drug efficacy in a cancer therapy model
- (2017) Marion Paolini et al. Nanomedicine-Nanotechnology Biology and Medicine
- Regulation of drug-metabolizing enzymes by local and systemic liver injuries
- (2016) Yan Guo et al. Expert Opinion on Drug Metabolism & Toxicology
- Recent Structural Insights into Cytochrome P450 Function
- (2016) F. Peter Guengerich et al. TRENDS IN PHARMACOLOGICAL SCIENCES
- CYP1B1 promotes tumorigenesis via altered expression of CDC20 and DAPK1 genes in renal cell carcinoma
- (2015) Yozo Mitsui et al. BMC CANCER
- miR-27b synergizes with anticancer drugs via p53 activation and CYP1B1 suppression
- (2015) Wenjing Mu et al. CELL RESEARCH
- Epigenetic Regulation of Cytochrome P450 Enzymes and Clinical Implication
- (2015) Xiaojing Tang et al. CURRENT DRUG METABOLISM
- Survey of Human Oxidoreductases and Cytochrome P450 Enzymes Involved in the Metabolism of Xenobiotic and Natural Chemicals
- (2014) Slobodan Rendic et al. CHEMICAL RESEARCH IN TOXICOLOGY
- Post-translational dual regulation of cytochrome P450 aromatase at the catalytic and protein levels by phosphorylation/dephosphorylation
- (2014) Takanori Hayashi et al. FEBS Journal
- How common are drug and gene interactions? Prevalence in a sample of 1143 patients with CYP2C9, CYP2C19 and CYP2D6 genotyping
- (2014) Paul Verbeurgt et al. PHARMACOGENOMICS
- Understanding and preventing drug–drug and drug–gene interactions
- (2014) Cara Tannenbaum et al. Expert Review of Clinical Pharmacology
- Mode of action and human relevance analysis for nuclear receptor-mediated liver toxicity: A case study with phenobarbital as a model constitutive androstane receptor (CAR) activator
- (2013) Clifford R. Elcombe et al. CRITICAL REVIEWS IN TOXICOLOGY
- Post-translational and Post-transcriptional Modifications of Pregnane X Receptor (PXR) in Regulation of the Cytochrome P450 Superfamily
- (2013) Tomas Smutny et al. CURRENT DRUG METABOLISM
- Cytochrome P450–mediated drug metabolism in the brain
- (2013) Sharon Miksys et al. JOURNAL OF PSYCHIATRY & NEUROSCIENCE
- Applications of CYP450 Testing in the Clinical Setting
- (2013) C. F. Samer et al. Molecular Diagnosis & Therapy
- Cytochrome P450 enzymes in drug metabolism: Regulation of gene expression, enzyme activities, and impact of genetic variation
- (2013) Ulrich M. Zanger et al. PHARMACOLOGY & THERAPEUTICS
- Phenobarbital Indirectly Activates the Constitutive Active Androstane Receptor (CAR) by Inhibition of Epidermal Growth Factor Receptor Signaling
- (2013) S. Mutoh et al. Science Signaling
- PHASE II DRUG METABOLIZING ENZYMES
- (2012) Petra Jancova et al. BIOMEDICAL PAPERS-OLOMOUC
- Modulation of Cytochrome-P450 Inhibition (CYP) in Drug Discovery: A Medicinal Chemistry Perspective
- (2012) Sanjay Kumar et al. CURRENT MEDICINAL CHEMISTRY
- Reactions and enzymes in the metabolism of drugs and other xenobiotics
- (2012) Bernard Testa et al. DRUG DISCOVERY TODAY
- Prediction of Cytochrome 450 Mediated Drug-Drug Interactions by Three-Dimensional Cultured Hepatocytes
- (2012) C. Shen et al. MINI-REVIEWS IN MEDICINAL CHEMISTRY
- Pharmacogenomics of the RNA World: Structural RNA Polymorphisms in Drug Therapy
- (2011) W Sadee et al. CLINICAL PHARMACOLOGY & THERAPEUTICS
- Novel advances in cytochrome P450 research
- (2011) Deepika Singh et al. DRUG DISCOVERY TODAY
- Quantitative Prediction of Human Pregnane X Receptor and Cytochrome P450 3A4 Mediated Drug-Drug Interaction in a Novel Multiple Humanized Mouse Line
- (2011) M. Hasegawa et al. MOLECULAR PHARMACOLOGY
- The neuroprotective enzyme CYP2D6 increases in the brain with age and is lower in Parkinson's disease patients
- (2011) Amandeep Mann et al. NEUROBIOLOGY OF AGING
- Simultaneous Absolute Quantification of 11 Cytochrome P450 Isoforms in Human Liver Microsomes by Liquid Chromatography Tandem Mass Spectrometry with In Silico Target Peptide Selection
- (2010) Hirotaka Kawakami et al. JOURNAL OF PHARMACEUTICAL SCIENCES
- The past, present and future of pharmacoepigenomics
- (2010) Magnus Ingelman-Sundberg et al. PHARMACOGENOMICS
- CNVs of human genes and their implication in pharmacogenetics
- (2009) I. Johansson et al. CYTOGENETIC AND GENOME RESEARCH
- Mechanistic aspects of CYP74 allene oxide synthases and related cytochrome P450 enzymes
- (2009) Alan R. Brash PHYTOCHEMISTRY
- Inhibition and induction of human cytochrome P450 enzymes: current status
- (2008) Olavi Pelkonen et al. ARCHIVES OF TOXICOLOGY
- CYP450 pharmacogenetics for personalizing cancer therapy
- (2008) Ron H.N. van Schaik DRUG RESISTANCE UPDATES
- Drug Related Genetic Polymorphisms Affecting Adverse Reactions to Methotrexate, Vinblastine, Doxorubicin and Cisplatin in Patients With Urothelial Cancer
- (2008) Norihiko Tsuchiya et al. JOURNAL OF UROLOGY
- Structural insights from a P450 Carrier Protein complex reveal how specificity is achieved in the P450BioI ACP complex
- (2008) M. J. Cryle et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Modes of heme binding and substrate access for cytochrome P450 CYP74A revealed by crystal structures of allene oxide synthase
- (2008) L. Li et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
Discover Peeref hubs
Discuss science. Find collaborators. Network.
Join a conversationFind the ideal target journal for your manuscript
Explore over 38,000 international journals covering a vast array of academic fields.
Search