Article
Food Science & Technology
Evelin Korcz, Laszlo Varga, Zoltan Kerenyi
Summary: This study established a correlation between total bacterial count (TBC) and exopolysaccharide (EPS) production in a specific Streptococcus thermophilus strain, showing that EPS biosynthesis is growth-related and can be monitored through TBC for quantification purposes.
LWT-FOOD SCIENCE AND TECHNOLOGY
(2021)
Article
Biochemistry & Molecular Biology
Yang Zhou, Yanhua Cui, Chao Suo, Qian Wang, Xiaojun Qu
Summary: The study showed that EPS-M2 produced by Streptococcus thermophilus CS6 exhibited good rheology, thermostability, and antioxidant activity, mainly composed of galactose, arabinose, and glucose. The EPS-M2 has potential applications in the food industry as a natural thickener, stabilizer, and antioxidant agent.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2021)
Article
Food Science & Technology
Xuefang Zhao, Qi Liang
Summary: This study evaluated the effects of probiotic Lactobacillus plantarum MC5 on the quality, antioxidant activity, and storage stability of yogurt. The results showed that adding MC5 can improve the rheological properties, texture, and antioxidant activity of yogurt. The study also found that MC5 can promote the growth of Streptococcus thermophilus. Therefore, L. plantarum MC5 has potential for industrial application in milk fermentation.
Article
Agriculture, Multidisciplinary
Ling Li, Ling Zhou, Xuemin Liu, Jinyan Gong, Gongnian Xiao
Summary: This study isolated and characterized Streptococcus thermophilus with high β-galactosidase activity and used it as a starter culture with Lactobacillus delbrueckii subsp. bulgaricus to make yogurt. The optimal fermentation ratio and temperature were found to be 2:1 and 42℃, respectively, leading to better organoleptic and physical properties of the yogurt. Higher lactobacilli population was observed in yogurt fermented at 37℃, and yogurt with a ratio of 2:1 starter cultures utilized lactose more effectively. The sensory properties of the yogurt remained unaffected at lower fermentation temperatures of 30 and 37℃.
JOURNAL OF THE SCIENCE OF FOOD AND AGRICULTURE
(2023)
Article
Biochemistry & Molecular Biology
Luyao Xiao, Yao Yang, Shuo Han, Xin Rui, Kai Ma, Changliang Zhang, Guangxian Wang, Wei Li
Summary: The study analyzed the structure of exo-polysaccharides (EPS) from Lacticaseibacillus paracasei S-NB and demonstrated the importance of genes associated with EPS biosynthesis in strain surface characteristics and cell-host interaction. The results showed that the genes S-NB_2176 and S-NB_2175 played a significant role in strain surface characteristics and host cell interaction.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2023)
Article
Agriculture, Multidisciplinary
Yang Zhou, Yanhua Cui, Xiaojun Qu
Summary: This study investigated the regulatory mechanisms of EPS biosynthesis in Streptococcus thermophilus CS6 and found that soy peptone and moderate pH conditions contribute to high EPS yield. Factors such as maltose, soy peptone, and initial pH greatly influence the EPS production in CS6. Differential gene expression related to carbohydrate metabolism plays a crucial role in regulating EPS biosynthesis.
JOURNAL OF THE SCIENCE OF FOOD AND AGRICULTURE
(2022)
Article
Biochemistry & Molecular Biology
Wei Xia, Jin Han, Shiming Zhu, Yilin Wang, Wenqing Zhang, Zhengjun Wu
Summary: EPS53, a homogeneous exopolysaccharide (EPS), was isolated from Streptococcus thermophiles XJ53 fermented in skimmed milk and had a high molecular weight and a specific repeating structural unit. EPS53-D, obtained by deproteinization using TCA, had a lower molecular weight but the same repeating structural unit. EPS53 exhibited stronger immune activity than EPS53-D, indicating the importance of molecular weight in EPS activity. TCA treatment may affect the activities of native EPSs produced by fermentation.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2023)
Article
Food Science & Technology
Amal Bakr Shori, Chin Wai Peng, Elham Bagheri, Ahmad Salihin Baba
Summary: The presence of plant water extracts in yogurt production positively affected the fermentation process, promoted microbial growth, enhanced proteolysis of milk protein, and induced EPS production. Additionally, plant extracts increased total solids content and water holding capacity in yogurt, showing potential in improving yogurt quality.
INTERNATIONAL JOURNAL OF FOOD ENGINEERING
(2021)
Article
Biochemistry & Molecular Biology
Teng-Gen Hu, Feng-Xiang Tan, Lu Li, Ke-Jing An, Bo Zou, Jing Wen, Ji-Jun Wu, Geng-Sheng Xiao, Yuan-Shan Yu, Yu-Juan Xu
Summary: Litchi polysaccharide Lzp2-2 promotes EPS production by Weissella confusa and improves the viscosity, texture, mouthfeel, and flavor of yoghurt.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2023)
Article
Microbiology
Junrui Wu, Danli Yan, Yumeng Liu, Xue Luo, Yang Li, Chengxu Cao, Mo Li, Qi Han, Cong Wang, Rina Wu, Lanwei Zhang
Summary: A novel EPS was extracted from Leuconostoc mesenteroides Shen Nong's (SN)-8, showing potential antioxidant and anticancer effects through structural characterization and experimental results.
FRONTIERS IN MICROBIOLOGY
(2021)
Article
Biochemistry & Molecular Biology
Anna Maciejewska, Czeslaw Lugowski, Jolanta Lukasiewicz
Summary: Streptococcus gallolyticus subspecies gallolyticus is a facultative pathogen associated with bacteraemia, infective endocarditis, and sepsis that has been linked with colorectal cancer. Its major sugar antigen, the exopolysaccharide (EPS), is a potential virulence factor.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2022)
Article
Biochemistry & Molecular Biology
Juanjuan Tian, Xiaomeng Wang, Xueliang Zhang, Cangping Zhang, Xiaohong Chen, Mingsheng Dong, Xin Rui, Qiuqin Zhang, Yong Fang, Wei Li
Summary: Two exopolysaccharide fractions (EPS1 and EPS2) were isolated from Paecilomyces cicadae TJJ 1213, with mannose and galactose as main components. Both EPS1 and EPS2 showed potential in protecting PC12 cells from oxidative stress and could potentially serve as therapeutic agents for neuronal disorders.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2021)
Article
Food Science & Technology
Jie Xiong, Jia-jia Yu, Dong-mei Liu, Jia-Juan Wu, Ming-Hua Liang, Jun Tang, Yi-Qian Xu
Summary: In this study, a novel polysaccharide EPS-1 was isolated from yogurt, and it showed potential for treating colitis based on animal experiments.
JOURNAL OF FUNCTIONAL FOODS
(2023)
Article
Chemistry, Applied
Xiaomeng Wang, Mengjia Xu, Danling Xu, Kai Ma, Changliang Zhang, Guangxian Wang, Mingsheng Dong, Wei Li
Summary: This study investigated the structure and function of exopolysaccharide (EPS) extracted from Lactobacillus helveticus SNA12. The EPS was found to be rich in galactose and glucose and contained specific repeat units. Scanning electron microscope analysis showed that the EPS had a tight structure with a smooth and uneven surface. Furthermore, the EPS exhibited prebiotic effects by modulating the gut microbiota composition and enhancing short-chain fatty acid production.
CARBOHYDRATE POLYMERS
(2022)
Article
Food Science & Technology
Zitong Ding, Jiandui Mi, Jianwei Zhou, Wencan Ke, Xusheng Guo
Summary: This study found diverse bacterial and fungal species in the traditional fermented yak milk from different regions of the Qinghai-Tibetan plateau. Although microbial compositions varied among ecotopes, there were no correlations between predominant species and environmental factors. The harsh environment in the western region had an impact on microbial compositions in the fermented yak milk.
LWT-FOOD SCIENCE AND TECHNOLOGY
(2022)
Article
Biochemistry & Molecular Biology
Wei-Han Hui, Yen-Lin Chen, Shu-Wei Chang
Summary: Crosslinking affects the mechanical behavior and tissue metabolism of collagen-based tissues. Aging and diabetes alter the crosslinking type and density, thus changing tissue properties. High-connectivity enzymatic crosslinking and advanced-glycation end-products result in uniform deformation under daily activity, while low-connectivity enzymatic crosslinking does not. High-connectivity model displays more sliding, while AGEs induce instability in structures near the binding sites.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Article
Biochemistry & Molecular Biology
Yao-Bin Ma, Xiao-Qiu Zhou, Wei-Dan Jiang, Pei Wu, Yang Liu, Shu-Wei Li, Ling Tang, Lu Zhang, Hai-Feng Mi, Lin Feng
Summary: Tea polyphenols (TPs) are an inexpensive feed additive that can protect the gill function of fish against Flavobacterium columnare (F. columnare) through various mechanisms, including suppression of oxidative stress, apoptosis, and inflammation.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Article
Biochemistry & Molecular Biology
Yan-Jia Guo, Jing-Ru Pang, Yu Zhang, Zhong-Rui Li, Xiao-Lin Zi, Hong-Min Liu, Ning Wang, Li-Juan Zhao, Ya Gao, Bo Wang, Piet Herdewijn, Cheng-Yun Jin, Ying Liu, Yi-Chao Zheng
Summary: This study identifies the conjugation of NEDD8 to LSD1 and its impact on GC cells, revealing the significance of LSD1 neddylation in GC.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Review
Biochemistry & Molecular Biology
Geum-Jae Jeong, Fazlurrahman Khan, Nazia Tabassum, Young-Mog Kim
Summary: Vibrio species are motile gram-negative bacteria commonly found in aquatic environments. They can adapt to environmental fluctuations and develop protective mechanisms against host immune systems. Different types of sigma and anti-sigma factors play important roles in regulating gene expression and virulence in Vibrio species.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Article
Biochemistry & Molecular Biology
Zahra Mohammadbagheri, Behrooz Movahedi, Shaghayegh Saeedi, Abbas Rahmati
Summary: In this study, a reusable biobased composite hydrogel was successfully synthesized and used for the removal of Tl(I) from aqueous solutions. The hydrogel exhibited high adsorption capacity and thermal stability, and the adsorption process was found to be thermodynamically spontaneous. The results demonstrated that the hydrogel can be reused multiple times without significant loss of its adsorption capacity.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Article
Biochemistry & Molecular Biology
Iqra Batool, Muhammad Imran, Ayesha Anwar, Farhan Ahmed Khan, Afrah E. Mohammed, Ashwag Shami, Hafiz Iqbal
Summary: Enzyme immobilization on ZnO/SnO2 and ZnO/SnO2/SA nanocomposites was studied, and the catalytic and biochemical characteristics of the immobilized enzyme were investigated. The results showed that ZnO/SnO2 and ZnO/SnO2/SA nanostructures are suitable carriers for enzyme immobilization.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Article
Biochemistry & Molecular Biology
Elias Mosaffa, Dhruvi Patel, Nasim Amiri Ramsheh, Rishikumar Indravadan Patel, Atanu Banerjee, Hossein Ghafuri
Summary: In this study, a unique 3D bead structure of adsorbent, composed of bacterial cellulose microfilaments reinforced chitosan adorned with melamine 2D plates, was synthesized for anionic dye removal. The adsorbent showed high specific surface area and abundant functional groups, resulting in exceptional adsorption capacity. The characteristics and optimal conditions of the adsorbent were assessed and analyzed.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Article
Biochemistry & Molecular Biology
Carolina Gismene, Jorge Enrique Hernandez Gonzalez, Marilia de Freitas Calmon, Andrey Fabricio Ziem Nascimento, Angela Rocio Nino Santisteban, Felipe Antunes Calil, Alana Della Torre da Silva, Paula Rahal, Rejane Maira Goes, Raghuvir Krishnaswamy Arni, Ricardo Barros Mariutti
Summary: Mammaliicoccus sciuri, a bacterium of clinical and veterinary relevance, expresses the virulence factor Exfoliative Toxin C (ExhC), which binds specifically to desmoglein-1 (Dsg1) and plays a role in tissue integrity. This study investigates the necrotic activity of ExhC and identifies a variant lacking necrotic potential but retaining enzymatic activity through mutagenesis experiments and crystal structure determination.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Article
Biochemistry & Molecular Biology
Bibhas K. Bhunia, Ashutosh Bandyopadhyay, Souradeep Dey, Biman B. Mandal
Summary: Intervertebral disc degeneration is a major cause of chronic low back pain and disability. Researchers have developed a bioactive silk-based hybrid hydrogel system functionalized with decellularized human Wharton's jelly extracellular matrix as bioactive cues. The hydrogels mimic the rheological and mechanical properties of the native nucleus pulposus tissue and support cell viability, proliferation, and tissue maturation.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Article
Biochemistry & Molecular Biology
Qun Zhang, Yonggan Yan, Zhao Li, Jing Du, Kai Zhang, Liguo Zhang, Ting Wang, Alberto Bianco, Shaohua Ge, Baojin Ma
Summary: A new crosslinking strategy has been devised to construct injectable sodium alginate hydrogels, which can be regulated for injectability and have great potential in biomedical applications.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Article
Biochemistry & Molecular Biology
Seong Eun Hong, Ji-Soo Lee, Hyeon Gyu Lee
Summary: The potential of multi-layer nanoemulsions for improving the cellular uptake, antioxidant activity, and in vitro bioaccessibility of alpha-tocopherol was examined. The results showed that the multi-layer nanoemulsions significantly enhanced the cellular uptake and antioxidant activity of alpha-tocopherol compared to free coumarin 6. Furthermore, the use of chitosan and dextran sulfate as wall materials in the multi-layer nanoemulsions led to even higher cellular uptake, in vitro bioaccessibility, and antioxidant activity of alpha-tocopherol.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Article
Biochemistry & Molecular Biology
Jingjing Yu, Yanhui Zhang, Ruoning Zhang, Yanxiang Gao, Like Mao
Summary: High internal phase emulsions (HIPEs) based on beeswax (BW) oleogels and octenyl succinic acid starch (OSA starch) were prepared by a simple one-step method. The results showed that oleogelation improved the stability and encapsulation capability of the HIPEs, which is significant for the development of novel healthy food.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Review
Biochemistry & Molecular Biology
Bi-Feng Yao, Xiu-Ju Luo, Jun Peng
Summary: The balanced and continuous fission and fusion of mitochondria, regulated by OPA1, are important for maintaining mitochondrial dynamics in cardiovascular disorders. Understanding the role of OPA1 in mitochondrial fusion can provide insights into the pathogenesis of cardiovascular diseases.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Review
Biochemistry & Molecular Biology
Gokul Paramasivam, Anandhavelu Sanmugam, Vishnu Vardhan Palem, Murugan Sevanan, Ananda Babu Sairam, Nachiappan Nachiappan, Buhyun Youn, Jung Sub Lee, Muthuchamy Nallal, Kang Hyun Park
Summary: Nanomaterials are being used to deliver therapeutic agents in living systems. Different nanotechnological applications such as immunosensors, immune assays, and drug delivery are being implemented using nanotechnology. Genomics plays a crucial role in selecting appropriate drugs for personalized cancer therapy. It helps in analyzing gene and protein expression, disease classification, and designing disease models. Delivering drugs to specific areas using nanoparticles is a challenging issue.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Article
Biochemistry & Molecular Biology
Jing Li, Wei Wang, Han Wu, Feng Peng, Hui Gao, Ying Guan
Summary: In this study, CMH-based CPF films were prepared and their thermal and barrier properties were successfully regulated. The tensile strength and water vapor barrier property of CPF films were significantly improved, making them promising for food packaging applications.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)