标题
TLRs in COVID-19: How they drive immunopathology and the rationale for modulation
作者
关键词
-
出版物
Innate Immunity
Volume 27, Issue 7-8, Pages 503-513
出版商
SAGE Publications
发表日期
2021-11-20
DOI
10.1177/17534259211051364
参考文献
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注意：仅列出部分参考文献，下载原文获取全部文献信息。- MDA5 Governs the Innate Immune Response to SARS-CoV-2 in Lung Epithelial Cells
- (2021) Xin Yin et al. Cell Reports
- SARS-CoV-2 spike protein interacts with and activates TLR41
- (2021) Yingchi Zhao et al. CELL RESEARCH
- SARS‐CoV‐2 ORF9b antagonizes type I and III interferons by targeting multiple components of the RIG‐I/MDA‐5–MAVS, TLR3–TRIF, and cGAS–STING signaling pathways
- (2021) Lulu Han et al. JOURNAL OF MEDICAL VIROLOGY
- TLR2 senses the SARS-CoV-2 envelope protein to produce inflammatory cytokines
- (2021) Min Zheng et al. NATURE IMMUNOLOGY
- SARS-CoV-2 in severe COVID-19 induces a TGF-β-dominated chronic immune response that does not target itself
- (2021) Marta Ferreira-Gomes et al. Nature Communications
- Development of epitope‐based peptide vaccine against novel coronavirus 2019 (SARS‐COV‐2): Immunoinformatics approach
- (2020) Manojit Bhattacharya et al. JOURNAL OF MEDICAL VIROLOGY
- Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China
- (2020) Chaolin Huang et al. LANCET
- Clinical Characteristics of Coronavirus Disease 2019 in China
- (2020) Wei-jie Guan et al. NEW ENGLAND JOURNAL OF MEDICINE
- Imbalanced Host Response to SARS-CoV-2 Drives Development of COVID-19
- (2020) Daniel Blanco-Melo et al. CELL
- Heightened Innate Immune Responses in the Respiratory Tract of COVID-19 Patients
- (2020) Zhuo Zhou et al. Cell Host & Microbe
- A Dynamic Immune Response Shapes COVID-19 Progression
- (2020) Eugenia Ziying Ong et al. Cell Host & Microbe
- CD24Fc protects against viral pneumonia in simian immunodeficiency virus-infected Chinese rhesus monkeys
- (2020) Ren-Rong Tian et al. Cellular & Molecular Immunology
- COVID-19: A New Virus, but a Familiar Receptor and Cytokine Release Syndrome
- (2020) Toshio Hirano et al. IMMUNITY
- Immunopathological characteristics of coronavirus disease 2019 cases in Guangzhou, China
- (2020) Mingkai Tan et al. IMMUNOLOGY
- In silico studies on the comparative characterization of the interactions of SARS‐CoV‐2 spike glycoprotein with ACE‐2 receptor homologs and human TLRs
- (2020) Abhigyan Choudhury et al. JOURNAL OF MEDICAL VIROLOGY
- Consider TLR5 for new therapeutic development against COVID‐19
- (2020) Chiranjib Chakraborty et al. JOURNAL OF MEDICAL VIROLOGY
- Triple combination of interferon beta-1b, lopinavir–ritonavir, and ribavirin in the treatment of patients admitted to hospital with COVID-19: an open-label, randomised, phase 2 trial
- (2020) Ivan Fan-Ngai Hung et al. LANCET
- Clinical course and risk factors for mortality of adult inpatients with COVID-19 in Wuhan, China: a retrospective cohort study
- (2020) Fei Zhou et al. LANCET
- Structure of Mpro from SARS-CoV-2 and discovery of its inhibitors
- (2020) Zhenming Jin et al. NATURE
- Covid-19 in Critically Ill Patients in the Seattle Region — Case Series
- (2020) Pavan K. Bhatraju et al. NEW ENGLAND JOURNAL OF MEDICINE
- Interferon-α2b Treatment for COVID-19
- (2020) Qiong Zhou et al. Frontiers in Immunology
- Pathogenic T-cells and inflammatory monocytes incite inflammatory storms in severe COVID-19 patients
- (2020) Yonggang Zhou et al. National Science Review
- Association of Cardiac Injury With Mortality in Hospitalized Patients With COVID-19 in Wuhan, China
- (2020) Shaobo Shi et al. JAMA Cardiology
- Characterization of the Inflammatory Response to Severe COVID-19 Illness
- (2020) Oliver J McElvaney et al. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
- Inducible Epithelial Resistance Against Coronavirus Pneumonia in Mice
- (2020) Scott E Evans et al. AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY
- Efficacy and safety of interferon β-1a in treatment of severe COVID-19: A randomized clinical trial
- (2020) Effat Davoudi-Monfared et al. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
- Dysregulated adaptive immune response contributes to severe COVID-19
- (2020) Kuai Yu et al. CELL RESEARCH
- Possible SARS-coronavirus 2 inhibitor revealed by simulated molecular docking to viral main protease and host toll-like receptor
- (2020) Xiaopeng Hu et al. Future Virology
- Presence of Genetic Variants Among Young Men With Severe COVID-19
- (2020) Caspar I. van der Made et al. JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION
- A Case for Targeting Th17 Cells and IL-17A in SARS-CoV-2 Infections
- (2020) Marika Orlov et al. JOURNAL OF IMMUNOLOGY
- Presepsin as a predictive biomarker of severity in COVID‐19: A case series
- (2020) Ai Fukada et al. JOURNAL OF MEDICAL VIROLOGY
- Extrapulmonary manifestations of COVID-19
- (2020) Aakriti Gupta et al. NATURE MEDICINE
- Impaired type I interferon activity and inflammatory responses in severe COVID-19 patients
- (2020) Jérôme Hadjadj et al. SCIENCE
- Type III interferons disrupt the lung epithelial barrier upon viral recognition
- (2020) Achille Broggi et al. SCIENCE
- Biological sex impacts COVID-19 outcomes
- (2020) Sabra L. Klein et al. PLoS Pathogens
- Ultra-High-Throughput Clinical Proteomics Reveals Classifiers of COVID-19 Infection
- (2020) Christoph B. Messner et al. Cell Systems
- Targeting innate immunity by blocking CD14: Novel approach to control inflammation and organ dysfunction in COVID-19 illness
- (2020) Thomas R. Martin et al. EBioMedicine
- Longitudinal COVID-19 profiling associates IL-1RA and IL-10 with disease severity and RANTES with mild disease
- (2020) Yan Zhao et al. JCI Insight
- Immune Phenotyping Based on the Neutrophil-to-Lymphocyte Ratio and IgG Level Predicts Disease Severity and Outcome for Patients With COVID-19
- (2020) Bicheng Zhang et al. Frontiers in Molecular Biosciences
- Antigen-Specific Adaptive Immunity to SARS-CoV-2 in Acute COVID-19 and Associations with Age and Disease Severity
- (2020) Carolyn Rydyznski Moderbacher et al. CELL
- Imiquimod - A toll like receptor 7 agonist - Is an ideal option for management of COVID 19
- (2020) Athina Angelopoulou et al. ENVIRONMENTAL RESEARCH
- Type I interferon susceptibility distinguishes SARS-CoV-2 from SARS-CoV.
- (2020) Kumari G. Lokugamage et al. JOURNAL OF VIROLOGY
- Effect of Tocilizumab vs Usual Care in Adults Hospitalized With COVID-19 and Moderate or Severe Pneumonia
- (2020) Olivier Hermine et al. JAMA Internal Medicine
- Effect of Tocilizumab vs Standard Care on Clinical Worsening in Patients Hospitalized With COVID-19 Pneumonia
- (2020) Carlo Salvarani et al. JAMA Internal Medicine
- Levels of Soluble CD14 and Tumor Necrosis Factor Receptors 1 and 2 may be predictive of death in Severe Coronavirus Disease 2019 (COVID-19)
- (2020) Emily R Bowman et al. JOURNAL OF INFECTIOUS DISEASES
- Host DDX Helicases as Possible SARS-CoV-2 Proviral Factors: A Structural Overview of Their Hijacking Through Multiple Viral Proteins
- (2020) Flavia Squeglia et al. Frontiers in Chemistry
- Intranasal and epicutaneous administration of Toll-like receptor 7 (TLR7) agonists provides protection against influenza A virus-induced morbidity in mice
- (2019) Eunice E. To et al. Scientific Reports
- Antagonism of dsRNA-Induced Innate Immune Pathways by NS4a and NS4b Accessory Proteins during MERS Coronavirus Infection
- (2019) Courtney E. Comar et al. mBio
- The Role of Interleukin 6 During Viral Infections
- (2019) Lauro Velazquez-Salinas et al. Frontiers in Microbiology
- Severe influenza pneumonitis in children with inherited TLR3 deficiency
- (2019) Hye Kyung Lim et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Toll-like receptor 5 agonist flagellin reduces influenza A virus replication independently of type I interferon and interleukin 22 and improves antiviral efficacy of oseltamivir
- (2019) Anne-France Georgel et al. ANTIVIRAL RESEARCH
- Ulinastatin Protects Against LPS-Induced Acute Lung Injury by Attenuating TLR4/NF-κB Pathway Activation and Reducing Inflammatory Mediators
- (2018) Chao Cao et al. SHOCK
- Serum High-Mobility-Group Box 1 as a Biomarker and a Therapeutic Target during Respiratory Virus Infections
- (2018) Mira C. Patel et al. mBio
- Toll-like receptor 4 in acute viral infection: Too much of a good thing
- (2018) Judith Olejnik et al. PLoS Pathogens
- By Capturing Inflammatory Lipids Released from Dying Cells, the Receptor CD14 Induces Inflammasome-Dependent Phagocyte Hyperactivation
- (2017) Ivan Zanoni et al. IMMUNITY
- TLR-7 agonist attenuates airway reactivity and inflammation through Nrf2-mediated antioxidant protection in a murine model of allergic asthma
- (2016) Ahmed Nadeem et al. INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY
- Novel strategies for targeting innate immune responses to influenza
- (2016) K A Shirey et al. Mucosal Immunology
- Type I interferons in viral control and immune regulation
- (2016) John R Teijaro Current Opinion in Virology
- Middle East Respiratory Coronavirus Accessory Protein 4a Inhibits PKR-Mediated Antiviral Stress Responses
- (2016) Huib H. Rabouw et al. PLoS Pathogens
- An avian influenza A (H7N9) virus vaccine candidate based on the fusion protein of hemagglutinin globular head and Salmonella typhimurium flagellin
- (2015) Li Song et al. BMC BIOTECHNOLOGY
- Disease-Promoting Effects of Type I Interferons in Viral, Bacterial, and Coinfections
- (2015) Sophia Davidson et al. JOURNAL OF INTERFERON AND CYTOKINE RESEARCH
- Toll-like receptor co-receptors as master regulators of the immune response
- (2015) Marco Di Gioia et al. MOLECULAR IMMUNOLOGY
- Severe infectious diseases of childhood as monogenic inborn errors of immunity
- (2015) Jean-Laurent Casanova PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Toll-Like Receptor 3 Signaling via TRIF Contributes to a Protective Innate Immune Response to Severe Acute Respiratory Syndrome Coronavirus Infection
- (2015) Allison L. Totura et al. mBio
- Vaccine adjuvant uses of poly-IC and derivatives
- (2014) Karen AO Martins et al. Expert Review of Vaccines
- Cutting Edge: Genetic Variation inTLR1Is Associated with Pam3CSK4-Induced Effector T Cell Resistance to Regulatory T Cell Suppression
- (2014) Carmen Mikacenic et al. JOURNAL OF IMMUNOLOGY
- Toll-Like Receptor 1 Polymorphisms and Associated Outcomes in Sepsis After Traumatic Injury
- (2013) Callie M. Thompson et al. ANNALS OF SURGERY
- Toll-Like Receptors in Antiviral Innate Immunity
- (2013) Sandra N. Lester et al. JOURNAL OF MOLECULAR BIOLOGY
- The Immunobiology of Toll-Like Receptor 4 Agonists
- (2013) Julia K. Bohannon et al. SHOCK
- Intranasal Treatment with Poly(I{middle dot}C) Protects Aged Mice from Lethal Respiratory Virus Infections
- (2012) J. Zhao et al. JOURNAL OF VIROLOGY
- Systematic identification of type I and type II interferon-induced antiviral factors
- (2012) S.-Y. Liu et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Toll-like Receptors and Their Crosstalk with Other Innate Receptors in Infection and Immunity
- (2011) Taro Kawai et al. IMMUNITY
- RIG-I like receptors and their signaling crosstalk in the regulation of antiviral immunity
- (2011) Hilario J Ramos et al. Current Opinion in Virology
- Innate and adaptive immune responses to viral infection and vaccination
- (2011) Taiki Aoshi et al. Current Opinion in Virology
- Intracellular Toll-like Receptors
- (2010) Amanda L. Blasius et al. IMMUNITY
- Clinical Features and Outcome of Patients With IRAK-4 and MyD88 Deficiency
- (2010) Capucine Picard et al. MEDICINE
- In Vitro Reconstitution of SARS-Coronavirus mRNA Cap Methylation
- (2010) Mickaël Bouvet et al. PLoS Pathogens
- Partial role of TLR4 as a receptor responding to damage-associated molecular pattern
- (2009) Kyung-Mi Lee et al. IMMUNOLOGY LETTERS
- Toll-like receptor 2 on inflammatory monocytes induces type I interferon in response to viral but not bacterial ligands
- (2009) Roman Barbalat et al. NATURE IMMUNOLOGY
- Sex differences in the Toll-like receptor–mediated response of plasmacytoid dendritic cells to HIV-1
- (2009) Angela Meier et al. NATURE MEDICINE
- CD24-Siglec G/10 discriminates danger- from pathogen-associated molecular patterns
- (2009) Yang Liu et al. TRENDS IN IMMUNOLOGY
- Toll-like Receptor 1 Polymorphisms Affect Innate Immune Responses and Outcomes in Sepsis
- (2008) Mark M. Wurfel et al. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
- Phosphatase SHP-1 promotes TLR- and RIG-I-activated production of type I interferon by inhibiting the kinase IRAK1
- (2008) Huazhang An et al. NATURE IMMUNOLOGY
- SARS-Coronavirus Replication Is Supported by a Reticulovesicular Network of Modified Endoplasmic Reticulum
- (2008) Kèvin Knoops et al. PLOS BIOLOGY
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