Early developing B cells undergo negative selection by central nervous system-specific antigens in the meninges

Functional characterization of the dural sinuses as a neuroimmune interface

(2021) Justin Rustenhoven et al.   CELL

Coupled analysis of transcriptome and BCR mutations reveals role of OXPHOS in affinity maturation

(2021) Dianyu Chen et al.   NATURE IMMUNOLOGY

Single-cell profiling of CNS border compartment leukocytes reveals that B cells and their progenitors reside in non-diseased meninges

(2021) David Schafflick et al.   NATURE NEUROSCIENCE

B cells in multiple sclerosis — from targeted depletion to immune reconstitution therapies

(2021) Maria T. Cencioni et al.   Nature Reviews Neurology

Skull and vertebral bone marrow are myeloid cell reservoirs for the meninges and CNS parenchyma

(2021) Andrea Cugurra et al.   SCIENCE

Heterogeneity of meningeal B cells reveals a lymphopoietic niche at the CNS borders

(2021) Simone Brioschi et al.   SCIENCE

Meningeal Immunity and Its Function in Maintenance of the Central Nervous System in Health and Disease

(2020) Kalil Alves de Lima et al.   Annual Review of Immunology

Cell circuits and niches controlling B cell development

(2019) Sandra Zehentmeier et al.   IMMUNOLOGICAL REVIEWS

A single-cell atlas of mouse brain macrophages reveals unique transcriptional identities shaped by ontogeny and tissue environment

(2019) Hannah Van Hove et al.   NATURE NEUROSCIENCE

B cell checkpoints in autoimmune rheumatic diseases

(2019) Samuel J. S. Rubin et al.   Nature Reviews Rheumatology

Comprehensive Integration of Single-Cell Data

(2019) Tim Stuart et al.   CELL

Impaired B‐cell tolerance checkpoints promote the development of autoimmune diseases and pathogenic autoantibodies

(2019) Eric Meffre et al.   IMMUNOLOGICAL REVIEWS

High-Dimensional Single-Cell Mapping of Central Nervous System Immune Cells Reveals Distinct Myeloid Subsets in Health, Aging, and Disease

(2018) Dunja Mrdjen et al.   IMMUNITY

Leukaemia hijacks a neural mechanism to invade the central nervous system

(2018) Hisayuki Yao et al.   NATURE

Direct vascular channels connect skull bone marrow and the brain surface enabling myeloid cell migration

(2018) Fanny Herisson et al.   NATURE NEUROSCIENCE

Panoptic imaging of transparent mice reveals whole-body neuronal projections and skull–meninges connections

(2018) Ruiyao Cai et al.   NATURE NEUROSCIENCE

Multiplex, quantitative cellular analysis in large tissue volumes with clearing-enhanced 3D microscopy (Ce3D)

(2017) Weizhe Li et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Generation of a whole-brain atlas for the cholinergic system and mesoscopic projectome analysis of basal forebrain cholinergic neurons

(2017) Xiangning Li et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Checkpoints that control B cell development

(2015) Fritz Melchers   JOURNAL OF CLINICAL INVESTIGATION

A dural lymphatic vascular system that drains brain interstitial fluid and macromolecules

(2015) Aleksanteri Aspelund et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Structural and functional features of central nervous system lymphatic vessels

(2015) Antoine Louveau et al.   NATURE

Microbial colonization influences early B-lineage development in the gut lamina propria

(2013) Duane R. Wesemann et al.   NATURE