Regulatory function of interferon‐inducible 44‐like for hepatitis B virus covalently closed circular DNA in primary human hepatocytes

Functional Comparison of IFN‐α Subtypes Reveals Potent HBV Suppression by a Concerted Action of IFN‐α and ‐γ Signaling

(2020) Jieliang Chen et al.   HEPATOLOGY

A global scientific strategy to cure hepatitis B

(2019) Peter A Revill et al.   Lancet Gastroenterology & Hepatology

NOVEL FUNCTIONS OF THE INTERFERON-INDUCED PROTEIN 44-LIKE (IFI44L) AS A FEEDBACK REGULATOR OF HOST ANTIVIRAL RESPONSES

(2019) Marta L. DeDiego et al.   JOURNAL OF VIROLOGY

Revisiting Hepatitis B Virus: Challenges of Curative Therapies

(2019) Jianming Hu et al.   JOURNAL OF VIROLOGY

Interferon-Induced Protein 44 Interacts with Cellular FK506-Binding Protein 5, Negatively Regulates Host Antiviral Responses, and Supports Virus Replication

(2019) Marta L. DeDiego et al.   mBio

Comparison of tenofovir and entecavir on the risk of hepatocellular carcinoma and mortality in treatment-naïve patients with chronic hepatitis B in Korea: a large-scale, propensity score analysis

(2019) Sung Won Lee et al.   GUT

Molecular signature of hepatitis B virus regulation by interferon‐γ in primary human hepatocytes

(2019) Takuto Nosaka et al.   HEPATOLOGY RESEARCH

Safety, efficacy and pharmacodynamics of vesatolimod (GS-9620) in virally suppressed patients with chronic hepatitis B

(2018) Harry L.A. Janssen et al.   JOURNAL OF HEPATOLOGY

Development of Direct-acting Antiviral and Host-targeting Agents for Treatment of Hepatitis B Virus Infection

(2018) Yuchen Xia et al.   GASTROENTEROLOGY

Intrahepatic innate immune response pathways are downregulated in untreated chronic hepatitis B

(2017) Fanny Lebossé et al.   JOURNAL OF HEPATOLOGY

Interferon-γ and Tumor Necrosis Factor-α Produced by T Cells Reduce the HBV Persistence Form, cccDNA, Without Cytolysis

(2016) Yuchen Xia et al.   GASTROENTEROLOGY

Cleaved c-FLIP mediates the antiviral effect of TNF-α against hepatitis B virus by dysregulating hepatocyte nuclear factors

(2016) Yong Kwang Park et al.   JOURNAL OF HEPATOLOGY

Attacking hepatitis B virus cccDNA – The holy grail to hepatitis B cure

(2016) Julie Lucifora et al.   JOURNAL OF HEPATOLOGY

Requirements for global elimination of hepatitis B: a modelling study

(2016) Shevanthi Nayagam et al.   LANCET INFECTIOUS DISEASES

HBV cccDNA: viral persistence reservoir and key obstacle for a cure of chronic hepatitis B

(2015) Michael Nassal   GUT

Specific and Nonhepatotoxic Degradation of Nuclear Hepatitis B Virus cccDNA

(2014) J. Lucifora et al.   SCIENCE

Enhancing Virus-Specific Immunity In Vivo by Combining Therapeutic Vaccination and PD-L1 Blockade in Chronic Hepadnaviral Infection

(2014) Jia Liu et al.   PLoS Pathogens

Targeting Hepatitis B Virus With CRISPR/Cas9

(2014) Christoph Seeger et al.   Molecular Therapy-Nucleic Acids

The entry inhibitor Myrcludex-B efficiently blocks intrahepatic virus spreading in humanized mice previously infected with hepatitis B virus

(2012) Tassilo Volz et al.   JOURNAL OF HEPATOLOGY

Control of hepatitis B virus at the level of transcription

(2010) M. Quasdorff et al.   JOURNAL OF VIRAL HEPATITIS

Early kinetics of innate and adaptive immune responses during hepatitis B virus infection

(2009) P Fisicaro et al.   GUT

Differential Transcriptional Responses to Interferon-α and Interferon-γ in Primary Human Hepatocytes

(2009) Xiao-Song He et al.   JOURNAL OF INTERFERON AND CYTOKINE RESEARCH

Repression of hepatitis B viral gene expression by transcription factor nuclear factor-kappaB

(2008) Yen-Cheng Lin et al.   CELLULAR MICROBIOLOGY