Exposure to imidacloprid induce oxidative stress, mitochondrial dysfunction, inflammation, apoptosis and mitophagy via NF-kappaB/JNK pathway in grass carp hepatocytes

New insights into crosstalk between apoptosis and necroptosis co-induced by chlorothalonil and imidacloprid in Ctenopharyngodon idellus kidney cells

(2021) Xiaojing Li et al.   SCIENCE OF THE TOTAL ENVIRONMENT

Cadmium exposure activates the PI3K/AKT signaling pathway through miRNA-21, induces an increase in M1 polarization of macrophages, and leads to fibrosis of pig liver tissue

(2021) Wei Cui et al.   ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY

Quercetin antagonizes imidacloprid-induced mitochondrial apoptosis through PTEN/PI3K/AKT in grass carp hepatocytes

(2021) Zhiruo Miao et al.   ENVIRONMENTAL POLLUTION

Protective effect of caffeic acid phenethyl ester against imidacloprid-induced hepatotoxicity by attenuating oxidative stress, endoplasmic reticulum stress, inflammation and apoptosis

(2020) Bo Shao et al.   PESTICIDE BIOCHEMISTRY AND PHYSIOLOGY

Antagonistic effect of selenium on lead-induced neutrophil apoptosis in chickens via miR-16-5p targeting of PiK3R1 and IGF1R

(2020) Kai Yin et al.   CHEMOSPHERE

Toxicogenomics provides insights to toxicity pathways of neonicotinoids to aquatic insect, Chironomus dilutus

(2020) Fenghua Wei et al.   ENVIRONMENTAL POLLUTION

Chlorpyrifos induces the apoptosis and necroptosis of L8824 cells through the ROS/PTEN/PI3K/AKT axis

(2020) Lanqiao Wang et al.   JOURNAL OF HAZARDOUS MATERIALS

CRIF1 overexpression facilitates tumor growth and metastasis through inducing ROS/NFκB pathway in hepatocellular carcinoma

(2020) Hulin Chang et al.   Cell Death & Disease

Metabolic disturbance in hippocampus and liver of mice: A primary response to imidacloprid exposure

(2020) Meilin Zheng et al.   Scientific Reports

Neonicotinoids caused oxidative stress and DNA damage in juvenile Chinese rare minnows (Gobiocypris rarus)

(2020) Xue Tian et al.   ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY

Pb exposure triggers MAPK-dependent inflammation by activating oxidative stress and miRNA-155 expression in carp head kidney

(2020) Hongyuan Jing et al.   FISH & SHELLFISH IMMUNOLOGY

Glyphosate induces lymphocyte cell dysfunction and apoptosis via regulation of miR-203 targeting of PIK3R1 in common carp (Cyprinus carpio L.)

(2020) Wei Wang et al.   FISH & SHELLFISH IMMUNOLOGY

Effects of imidacloprid on the oxidative stress, detoxification and gut microbiota of Chinese mitten crab, Eriocheir sinensis

(2020) Yuhang Hong et al.   SCIENCE OF THE TOTAL ENVIRONMENT

A nationwide study of occurrence and exposure assessment of neonicotinoid insecticides and their metabolites in drinking water of China

(2020) Gaga Mahai et al.   WATER RESEARCH

Imidacloprid poisoning case series: potential for liver injury

(2019) C. Sriapha et al.   CLINICAL TOXICOLOGY

Activation of BNIP3-mediated mitophagy protects against renal ischemia–reperfusion injury

(2019) Chengyuan Tang et al.   Cell Death & Disease

Tocilizumab attenuates acute lung and kidney injuries and improves survival in a rat model of sepsis via down-regulation of NF-κB/JNK: a possible role of P-glycoprotein

(2019) Yasmine F. Ibrahim et al.   INFLAMMOPHARMACOLOGY

Bees and pesticide regulation: Lessons from the neonicotinoid experience

(2019) Fabio Sgolastra et al.   BIOLOGICAL CONSERVATION

Hepatoprotective effects of zinc (II) via cytochrome P-450/reactive oxygen species and canonical apoptosis pathways after arsenite waterborne exposure in common carp

(2019) Hongjing Zhao et al.   CHEMOSPHERE

Avermectin inhibits neutrophil extracellular traps release by activating PTEN demethylation to negatively regulate the PI3K-ERK pathway and reducing respiratory burst in carp

(2019) Shufang Zheng et al.   JOURNAL OF HAZARDOUS MATERIALS

Melatonin enhances mitochondrial biogenesis and protects against rotenone‐induced mitochondrial deficiency in early porcine embryos

(2019) Ying‐Jie Niu et al.   JOURNAL OF PINEAL RESEARCH

Imidacloprid-induced liver fibrosis in quails via activation of the TGF-β1/Smad pathway

(2019) Yueying Lv et al.   SCIENCE OF THE TOTAL ENVIRONMENT

DNA damage and oxidative stress induced by imidacloprid exposure in different tissues of the Neotropical fish Prochilodus lineatus

(2018) Carlos Eduardo Delfino Vieira et al.   CHEMOSPHERE

Cadmium induces BNIP3-dependent autophagy in chicken spleen by modulating miR-33-AMPK axis

(2018) Menghao Chen et al.   CHEMOSPHERE

Arsenic-induced apoptosis in the p53-proficient and p53-deficient cells through differential modulation of NFkB pathway

(2018) Lei Yin et al.   FOOD AND CHEMICAL TOXICOLOGY

Mice lacking the cytochrome P450 (CYP)1B1 gene are less susceptible to hyperoxic lung injury than wild type

(2018) Alex C Veith et al.   TOXICOLOGICAL SCIENCES

DUSP1 alleviates cardiac ischemia/reperfusion injury by suppressing the Mff-required mitochondrial fission and Bnip3-related mitophagy via the JNK pathways

(2018) Qinhua Jin et al.   Redox Biology

Therapeutic effect of Sirtuin 3 on ameliorating nonalcoholic fatty liver disease: The role of the ERK-CREB pathway and Bnip3-mediated mitophagy

(2018) Ruibing Li et al.   Redox Biology

Trehalose prevents cadmium-induced hepatotoxicity by blocking Nrf2 pathway, restoring autophagy and inhibiting apoptosis

(2018) Zhong-Gui Gong et al.   JOURNAL OF INORGANIC BIOCHEMISTRY

The pharmacological regulation of cellular mitophagy

(2017) Nikolaos D Georgakopoulos et al.   Nature Chemical Biology

Evidence for indirect effects of pesticide seed treatments on weed seed banks in maize and soybean

(2016) Richard G. Smith et al.   AGRICULTURE ECOSYSTEMS & ENVIRONMENT

The apoptotic members CD95, BclxL and Bcl-2 cooperate to promote cell migration by inducing Ca2+ flux from the endoplasmic reticulum to mitochondria

(2016) A Fouqué et al.   CELL DEATH AND DIFFERENTIATION

BNIP3 Protein Suppresses PINK1 Kinase Proteolytic Cleavage to Promote Mitophagy

(2016) Tongmei Zhang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Mitochondrial permeability transition and its regulatory components are implicated in apoptosis of primary cultures of rat proximal tubular cells exposed to lead

(2015) Gang Liu et al.   ARCHIVES OF TOXICOLOGY

SIRT3-SOD2-mROS-dependent autophagy in cadmium-induced hepatotoxicity and salvage by melatonin

(2015) Huifeng Pi et al.   Autophagy

Mitochondrial autophagy: Origins, significance, and role of BNIP3 and NIX

(2015) Paul A. Ney   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Alteration in the cytokine levels and histopathological damage in common carp induced by glyphosate

(2015) Junguo Ma et al.   CHEMOSPHERE

Mitophagy defects arising from BNip3 loss promote mammary tumor progression to metastasis

(2015) A. H. Chourasia et al.   EMBO REPORTS

Contaminant-induced oxidative stress in fish: a mechanistic approach

(2015) Volodymyr I. Lushchak   FISH PHYSIOLOGY AND BIOCHEMISTRY

Oxidative Stress and DNA Damage Induced by Imidacloprid in Zebrafish (Danio rerio)

(2015) Weili Ge et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Cadmium-induced autophagy is mediated by oxidative signaling in PC-12 cells and is associated with cytoprotection

(2015) QI-WEN WANG et al.   Molecular Medicine Reports

Mitochondrial Function and Disturbances in the Septic Kidney

(2015) Samir M. Parikh et al.   SEMINARS IN NEPHROLOGY

Immunological and histological effects of exposure to imidacloprid insecticide in male albino rats

(2014) Mohamed Mohany   African Journal of Pharmacy and Pharmacology

OM85-BV Induced the Productions of IL-1β, IL-6, and TNF-α via TLR4- and TLR2-Mediated ERK1/2/NF-κB Pathway in RAW264.7 Cells

(2014) Hong Luan et al.   JOURNAL OF INTERFERON AND CYTOKINE RESEARCH

Ceftriaxone Protects Astrocytes from MPP+ via Suppression of NF-κB/JNK/c-Jun Signaling

(2014) Yunlong Zhang et al.   MOLECULAR NEUROBIOLOGY

The role of cell signalling in the crosstalk between autophagy and apoptosis

(2013) Laurence A. Booth et al.   CELLULAR SIGNALLING

Macro-Invertebrate Decline in Surface Water Polluted with Imidacloprid

(2013) Tessa C. Van Dijk et al.   PLoS One

Resveratrol induces apoptosis via a Bak-mediated intrinsic pathway in human lung adenocarcinoma cells

(2012) Weiwei Zhang et al.   CELLULAR SIGNALLING

Mitochondrial autophagy in neural function, neurodegenerative disease, neuron cell death, and aging

(2010) Yakup Batlevi et al.   NEUROBIOLOGY OF DISEASE

JNK1-Mediated Phosphorylation of Bcl-2 Regulates Starvation-Induced Autophagy

(2008) Yongjie Wei et al.   MOLECULAR CELL

Imidacloprid Induces Neurobehavioral Deficits and Increases Expression of Glial Fibrillary Acidic Protein in the Motor Cortex and Hippocampus in Offspring Rats Following in Utero Exposure

(2007) Mohamed B. Abou-Donia et al.   JOURNAL OF TOXICOLOGY AND ENVIRONMENTAL HEALTH-PART A-CURRENT ISSUES