Article
Biochemistry & Molecular Biology
Lei Tian, Yu Liu, Xiaofang Xu, Pengrui Jiao, Gaofei Hu, Yaqian Cui, Jixiang Chen, Yucheng Ma, Xi Jin, Kunjie Wang, Qun Sun
Summary: This study investigated the effect of Lactiplantibacillus plantarum J-15 on kidney stone formation and found that it reduces the formation of renal crystallization and urinary oxalic acid. It restores intestinal microflora and metabolic disorder, protects intestinal barrier function, and alleviates inflammation, suggesting that it could be a potential therapy for renal stones.
Article
Biotechnology & Applied Microbiology
Wei Liang, Yansong Gao, Yujuan Zhao, Lei Gao, Zijian Zhao, Zhongmei He, Shengyu Li
Summary: This study demonstrated the preventive effect of Lactiplantibacillus plantarum ELF051 on antibiotic-associated diarrhea, as well as its modulation of gut microbiota and suppression of inflammatory response.
PROBIOTICS AND ANTIMICROBIAL PROTEINS
(2023)
Article
Microbiology
Yu Liu, Xi Jin, Lei Tian, Zhongyu Jian, Yucheng Ma, Liang Cheng, Yaqian Cui, Hong Li, Qun Sun, Kunjie Wang
Summary: This study demonstrated the potential of Lactiplantibacillus plantarum N-1 probiotics in reducing renal calcium oxalate crystal deposition by regulating arginine metabolism in the gut microbiota. Furthermore, supplementation with N-1 also influenced the microbial community structure in the ileum and cecum.
FRONTIERS IN MICROBIOLOGY
(2021)
Article
Nutrition & Dietetics
Yushan Bu, Yisuo Liu, Tai Zhang, Yinxue Liu, Zhe Zhang, Huaxi Yi
Summary: Bacteriocins production is an important characteristic of probiotics, which can inhibit intestinal pathogens and regulate intestinal flora. In this study, orally administering bacteriocin-producing Lactiplantibacillus plantarum YRL45 to mice resulted in enhanced immune regulation system, maintenance of colon tissue morphology without inflammation, and increased expression of genes related to intestinal barrier function. Additionally, YRL45 supplementation increased the levels of immunoglobulins and beneficial bacteria while reducing pathogenic bacteria in the intestine of mice. These findings suggest that YRL45 has the potential to be developed as a novel probiotic to enhance intestinal immunity and balance intestinal flora.
Article
Food Science & Technology
Guanlan Liu, Israr Khan, Yuxi Li, Yun Yang, Xuerui Lu, Yafei Wang, Junxiang Li, Chunjiang Zhang
Summary: In this study, Lactiplantibacillus plantarum LZU-J-TSL6 with high GABA production was isolated from a Chinese fermented food. The effects of LZU-J-TSL6 on anxiety disorder were explored using mice as animal models. The results showed that LZU-J-TSL6 had the potential to colonize the intestine and significantly improved anxiety-like behavior in mice. LZU-J-TSL6 also increased GABA content in the mice hippocampus and restored markers related to anxiety. Additionally, it regulated intestinal microbiota imbalance, affected nerve pathways, and repaired the intestinal mucosal barrier. This study highlights the potential of LZU-J-TSL6 as a probiotic for improving anxiety disorders.
Article
Immunology
Leilei Yu, Lingyu Zhang, Hui Duan, Ruohan Zhao, Yue Xiao, Min Guo, Jianxin Zhao, Hao Zhang, Wei Chen, Fengwei Tian
Summary: The study found that Lactiplantibacillus plantarum CCFM8661 effectively reduced B[a]P-induced oxidative stress, improved behavioral performance, increased intestinal barrier integrity, and alleviated histopathological changes in mice. Additionally, CCFM8661 increased gut microbiota diversity and SCFA production.
FRONTIERS IN IMMUNOLOGY
(2021)
Article
Nutrition & Dietetics
Longyan Li, Lei Wu, Tong Jiang, Tingting Liang, Lingshuang Yang, Ying Li, He Gao, Jumei Zhang, Xinqiang Xie, Qingping Wu
Summary: Sleep deprivation can result in intestinal diseases, and L. plantarum 124, a probiotic, has been found to attenuate intestinal damage caused by sleep deprivation. This is achieved by modulating the gut microbiota to restore intestinal health.
Article
Nutrition & Dietetics
Yushan Bu, Yisuo Liu, Yinxue Liu, Jiayuan Cao, Zhe Zhang, Huaxi Yi
Summary: This study explored the effects of bacteriocin-producing Lactiplantibacillus plantarum Q7 and L. plantarum F3-2 on the intestinal barrier of mice. The results showed that L. plantarum Q7 promoted the expression of mucin MUC2 and up-regulated the gene expression of tight junction proteins and IgA/IgG release, enhancing the protective function of the intestinal barrier.
Article
Agriculture, Multidisciplinary
Xiaowei Xu, Shanji Liu, Yu Zhao, Mengqi Wang, Liehai Hu, Wenjuan Li, Hengyi Xu
Summary: Polysaccharides and probiotics can be combined to regulate gut microbiota and alleviate liver injury. The study found that the combination of Houttuynia cordata polysaccharide (HCP) and Lactiplantibacillus plantarum P101 can reduce oxidative stress and inflammatory injury in the liver by activating Nrf2 signals and inhibiting NF-kappa B signals. Furthermore, the combination increased the abundance of beneficial bacteria and reduced the pro-inflammatory bacteria in the gut microbiota. The findings suggest that polysaccharides combined with probiotics can regulate gut microbiota and alleviate liver injury.
JOURNAL OF THE SCIENCE OF FOOD AND AGRICULTURE
(2022)
Article
Food Science & Technology
Lijuan Zhang, Yuan Meng, Jiayi Li, Jiang Yu, Guangqing Mu, Yanfeng Tuo
Summary: This study compared the similarities and differences in the probiotic and physiological traits of Lactiplantibacillus plantarum Y42 in the biofilm and planktonic states. The findings showed that the strain in the biofilm state had higher survival and adhesion properties, as well as boosting immunity when orally administered to mice. The diversity and structure of the intestinal flora were altered regardless of the state of the strain.
Article
Food Science & Technology
Tao Wang, Panpan Wang, Li Yin, Xiuchao Wang, Yuanyuan Shan, Yanglei Yi, Yuan Zhou, Bianfang Liu, Xin Wang, Xin Lue
Summary: L. plantarum KX041 effectively improves colorectal cancer by modulating gut microbiota, reducing inflammation, maintaining intestinal permeability, and attenuating oxidative stress.
FOOD SCIENCE AND HUMAN WELLNESS
(2023)
Article
Biology
Elisa Maritan, Marialaura Gallo, Dagmar Srutkova, Anna Jelinkova, Oldrich Benada, Olga Kofronova, Nuno F. Silva-Soares, Tomas Hudcovic, Isaac Gifford, Jeffrey E. Barrick, Martin Schwarzer, Maria Elena Martino
Summary: The evolution of gut microbes in insects and mammals differs due to the influence of host diet and intrinsic factors in mammals. The symbiotic relationship between fruit flies and L. plantarum is mainly determined by the host diet, while the host's intrinsic factors play a critical role in the selection and evolution of gut microbes in mammals.
Article
Biochemistry & Molecular Biology
Emilija Brdaric, Dusanka Popovic, Svetlana Sokovic Bajic, Dina Tucovic, Jelena Mutic, Maja Cakic-Milosevic, Sladana Durdic, Maja Tolinacki, Aleksandra Popov Aleksandrov, Natasa Golic, Ivana Mirkov, Milica Zivkovic
Summary: Through experiments on rats, it was found that food supplemented with EPS-AN8 can reduce the levels of cadmium in the kidneys, liver, and blood, while enriching it in the feces. In addition, EPS-AN8 can reverse the effects of cadmium on oxidative stress, inflammation, and gut microbiota. Therefore, EPS-AN8 may be extremely significant in combating this toxic environmental pollutant.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)
Article
Biochemistry & Molecular Biology
Jarukan Lamubol, Nobuaki Ohto, Hiroshige Kuwahara, Masashi Mizuno
Summary: In this study, the anti-inflammatory effects of LP22A3 on DSS-induced colitis were evaluated, and it was found that LP22A3 administration led to increased production of TGF-beta and IL-10, as well as an increase in CD103(+) DCs and Foxp3(+) Treg cells in the small intestine. These cells secreted high levels of anti-inflammatory cytokines, contributing to protection against inflammation. Overall, oral administration of LP22A3 may serve as an alternative therapeutic strategy for inflammatory bowel disease.
Article
Microbiology
Eliska Valeckova, Li Sun, Helen Wang, Faruk Dube, Emma Ivarsson, Kamyar Mogodiniyai Kasmaei, Patrik Ellstrom, Helena Wall
Summary: This study evaluated the effects of daily intake of LP256 on C. jejuni loads in the ceca and feces of broilers and the changes in the gut microbiota. The results showed that LP256 significantly reduced C. jejuni colonization in the ceca at the beginning of the experiment, but no treatment effect was observed at the end. The colonization dynamics of C. jejuni and the cecal microbiota composition were not affected by LP256 intake.
FRONTIERS IN MICROBIOLOGY
(2023)
Article
Andrology
Yang Liu, Xiao-ying Pan, Xiang-xiang Zhang, Ji-lei Sun, Yin-hui Mao, Yong Yang, Zhi-tao Wei
Summary: This study aimed to investigate the role of YAP/TAZ-mediated mechanotransduction in mechanical therapy for the treatment of neurogenic erectile dysfunction (NED). The results showed that low-intensity pulsed ultrasound (LIPUS) can effectively improve penile erectile function in NED rats, possibly through the regulation of YAP/TAZ-mediated mechanotransduction.
