LETMD1 is required for mitochondrial structure and thermogenic function of brown adipocytes

DsbA-L deficiency in T cells promotes diet-induced thermogenesis through suppressing IFN-γ production

(2021) Haiyan Zhou et al.   Nature Communications

AIDA directly connects sympathetic innervation to adaptive thermogenesis by UCP1

(2021) Meng Shi et al.   NATURE CELL BIOLOGY

The cellular and functional complexity of thermogenic fat

(2021) Paul Cohen et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

LETMD1 Regulates Phagocytosis and Inflammatory Responses to Lipopolysaccharide via Reactive Oxygen Species Generation and NF-κB Activation in Macrophages

(2020) Su-Geun Lim et al.   JOURNAL OF IMMUNOLOGY

γδ T cells and adipocyte IL-17RC control fat innervation and thermogenesis

(2020) Bo Hu et al.   NATURE

Generation of mouse conditional knockout alleles in one step using the i-GONAD method

(2020) Renjie Shang et al.   GENOME RESEARCH

Innervation of thermogenic adipose tissue via a calsyntenin 3β–S100b axis

(2019) Xing Zeng et al.   NATURE

SIRT3 controls brown fat thermogenesis by deacetylation regulation of pathways upstream of UCP1

(2019) Rajaa Sebaa et al.   Molecular Metabolism

Comprehensive Integration of Single-Cell Data

(2019) Tim Stuart et al.   CELL

BCAA catabolism in brown fat controls energy homeostasis through SLC25A44

(2019) Takeshi Yoneshiro et al.   NATURE

Low- and high-thermogenic brown adipocyte subpopulations coexist in murine adipose tissue

(2019) Anying Song et al.   JOURNAL OF CLINICAL INVESTIGATION

A subpopulation of Bdnf-e1–expressing glutamatergic neurons in the lateral hypothalamus critical for thermogenesis control

(2019) He You et al.   Molecular Metabolism

Deconstructing Adipogenesis Induced by β3-Adrenergic Receptor Activation with Single-Cell Expression Profiling

(2018) Rayanne B. Burl et al.   Cell Metabolism

Cardiolipin Synthesis in Brown and Beige Fat Mitochondria Is Essential for Systemic Energy Homeostasis

(2018) Elahu G. Sustarsic et al.   Cell Metabolism

Mfn2 ablation causes an oxidative stress response and eventual neuronal death in the hippocampus and cortex

(2018) Sirui Jiang et al.   Molecular Neurodegeneration

p53 Functions in Adipose Tissue Metabolism and Homeostasis

(2018) Jelena Krstic et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Accumulation of succinate controls activation of adipose tissue thermogenesis

(2018) Evanna L. Mills et al.   NATURE

Secretin-Activated Brown Fat Mediates Prandial Thermogenesis to Induce Satiation

(2018) Yongguo Li et al.   CELL

Targeting thermogenesis in brown fat and muscle to treat obesity and metabolic disease

(2017) Matthias J. Betz et al.   Nature Reviews Endocrinology

Control of brown and beige fat development

(2016) Wenshan Wang et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

De Novo Reconstruction of Adipose Tissue Transcriptomes Reveals Long Non-coding RNA Regulators of Brown Adipocyte Development

(2015) Juan R. Alvarez-Dominguez et al.   Cell Metabolism

The brown fat secretome: metabolic functions beyond thermogenesis

(2015) Guo-Xiao Wang et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

SIRT1 enhances glucose tolerance by potentiating brown adipose tissue function

(2015) Marie Boutant et al.   Molecular Metabolism

Cholinergic neurons in the dorsomedial hypothalamus regulate mouse brown adipose tissue metabolism

(2015) Jae Hoon Jeong et al.   Molecular Metabolism

Inhibition of Notch signaling promotes browning of white adipose tissue and ameliorates obesity

(2014) Pengpeng Bi et al.   NATURE MEDICINE

Brown fat fuel utilization and thermogenesis

(2014) Kristy L. Townsend et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Brown adipose tissue derived VEGF-A modulates cold tolerance and energy expenditure

(2014) Kai Sun et al.   Molecular Metabolism

EBF2 Determines and Maintains Brown Adipocyte Identity

(2013) Sona Rajakumari et al.   Cell Metabolism

Impact of brown adipose tissue on body fatness and glucose metabolism in healthy humans

(2013) M Matsushita et al.   INTERNATIONAL JOURNAL OF OBESITY

Adipose tissue browning and metabolic health

(2013) Alexander Bartelt et al.   Nature Reviews Endocrinology

Fat cells directly sense temperature to activate thermogenesis

(2013) L. Ye et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The role of thyroid hormone and brown adipose tissue in energy homoeostasis

(2013) Antonio C Bianco et al.   Lancet Diabetes & Endocrinology

Down-regulation of OPA1 alters mouse mitochondrial morphology, PTP function, and cardiac adaptation to pressure overload

(2012) Jerome Piquereau et al.   CARDIOVASCULAR RESEARCH

Mechanism of Fatty-Acid-Dependent UCP1 Uncoupling in Brown Fat Mitochondria

(2012) Andriy Fedorenko et al.   CELL

Central Control of Brown Adipose Tissue Thermogenesis

(2012) Shaun F. Morrison et al.   Frontiers in Endocrinology

Hypoxia-Independent Angiogenesis in Adipose Tissues during Cold Acclimation

(2009) Yuan Xue et al.   Cell Metabolism

Initiation of myoblast to brown fat switch by a PRDM16–C/EBP-β transcriptional complex

(2009) Shingo Kajimura et al.   NATURE

Functional Brown Adipose Tissue in Healthy Adults

(2009) Kirsi A. Virtanen et al.   NEW ENGLAND JOURNAL OF MEDICINE

Genome-Wide RNAi Screen Identifies Letm1 as a Mitochondrial Ca2+/H+ Antiporter

(2009) D. Jiang et al.   SCIENCE