Article
Medicine, General & Internal
Francesco Fantin, Anna Giani, Monica Trentin, Andrea P. Rossi, Elena Zoico, Gloria Mazzali, Rocco Micciolo, Mauro Zamboni
Summary: The study evaluated the relationship between arterial stiffness indexes, comorbidity burden, and aging. It found significant correlations between arterial stiffness indexes and both age and comorbidity burden. Arterial stiffness parameters can provide additional insights into patients with significant comorbidity burdens as they age.
JOURNAL OF CLINICAL MEDICINE
(2022)
Article
Cardiac & Cardiovascular Systems
Hyo Eun Park, Goh Eun Chung, Heesun Lee, Min Joo Kim, Su-Yeon Choi, Wonjae Lee, Ji Won Yoon
Summary: This study evaluated the relationship between low skeletal muscle mass and cardio-ankle vascular index (CAVI) and found a significant and independent association between low muscle mass and increased CAVI. This suggests that low muscle mass should be considered in assessing the risk of atherosclerosis in asymptomatic individuals.
FRONTIERS IN CARDIOVASCULAR MEDICINE
(2022)
Article
Medicine, General & Internal
Anna Vegh, Adrienn Barczi, Orsolya Cseprekal, Eva Kis, Kata Kelen, Szilard Torok, Attila J. Szabo, Gyorgy S. Reusz
Summary: Pediatric renal transplant recipients have a high prevalence of hypertension, with controlled hypertension potentially impacting the evolution of GFR. It is suggested to enhance the control of hypertension to maintain renal transplant function.
FRONTIERS IN MEDICINE
(2021)
Article
Dentistry, Oral Surgery & Medicine
Kansurang Chansawang, Attawood Lertpimonchai, Nisachon Siripaiboonpong, Lalitsara Thienpramuk, Prin Vathesatogkit, Thosaphol Limpijankit, Orawan Charatkulangkun
Summary: The study found a significant dose-dependent association between the severity and extent of periodontitis and arterial stiffness measured by CAVI in Thai adults. Linear and logistic regression analysis demonstrated a significant relationship between CAVI and all periodontal variables.
CLINICAL ORAL INVESTIGATIONS
(2021)
Article
Chemistry, Analytical
Ladislav Soukup, Pavel Jurak, Josef Halamek, Ivo Viscor, Magdalena Matejkova, Pavel Leinveber, Vlastimil Vondra
Summary: This study aims to establish a methodology using multichannel bioimpedance to evaluate pulse waves in the whole body for assessing arterial stiffness and the cardiovascular system. The results showed that aortic pulse wave velocity (PWV) is age-dependent when measured using the left carotid as the proximal location, while PWV in the upper and lower limbs is independent of age. Additionally, PWV in the left femoral artery has comparable values to carotid-femoral values published previously.
Article
Physiology
Shuji Sato, Kazuhiro Shimizu, Mao Takahashi, Motoyuki Masai, Osamu Nagakawa, Junji Uchino, Toshihiro Suzuki, Yuka Sato, Noriko Iwai, Kohji Shirai
Summary: Blood pressure changes are frequently observed during hemodialysis (HD), but the mechanism is not fully understood. The cardio-ankle vascular index (CAVI) reflects arterial stiffness and can be independent of blood pressure. This study aimed to clarify the role of CAVI in regulating blood pressure during HD. The results showed that CAVI increased significantly during HD and correlated with water removal rate and blood pressure changes. Monitoring CAVI during HD may help distinguish the cause of blood pressure changes.
FRONTIERS IN PHYSIOLOGY
(2023)
Article
Medicine, General & Internal
Kaichi Kaneko, Daiki Sakai, Shuji Sato, Toshio Kinoshita, Kazuhiro Shimizu
Summary: A study found that glucocorticoid therapy temporarily exacerbates arterial stiffness in patients with rheumatic diseases, but eventually improves it. Particularly in young patients, glucocorticoids may improve arterial stiffness by reducing inflammation. The study also found that the lymphocyte-to-monocyte ratio before treatment may be a potential predictor of arterial stiffness.
JOURNAL OF CLINICAL MEDICINE
(2023)
Article
Cardiac & Cardiovascular Systems
Jie Wang, Rujia Miao, Zhiheng Chen, Jiangang Wang, Hong Yuan, Jing Li, Zheng Huang
Summary: This study identified a correlation between non-HDL-C and arterial stiffness, especially in younger individuals. The potential clinical benefits of reducing non-HDL-C concentration should be further investigated.
FRONTIERS IN CARDIOVASCULAR MEDICINE
(2022)
Article
Pediatrics
Maria Fernstrom, Emerald G. G. Heiland, Karin Kjellenberg, Marjan Ponten, Olga Tarassova, Gisela Nyberg, Bjorg Helgadottir, Maria M. M. Ekblom, Orjan Ekblom
Summary: The aim of this study was to evaluate the acute effects of physical activity breaks during prolonged sitting on arterial stiffness, cortisol and psychological factors in adolescents. The results indicated that arterial stiffness increased after frequent and short step up activity breaks, suggesting potential intensity-dependent effects of physical activity on vascular regulation in youth.
Article
Endocrinology & Metabolism
Stella Bernardi, Fabiola Giudici, Vincenzo Barbato, Lorenzo Zanatta, Andrea Grillo, Bruno Fabris
Summary: Current data on cardiovascular manifestations in patients with mild primary hyperparathyroidism (pHPT) show conflicting results. This study found that aortic stiffness is increased in patients with mild pHPT, but parathyroidectomy (PTX) significantly reduced arterial stiffness in these patients. Further research is needed to fully understand the impact of PTX on cardiovascular outcomes in mild pHPT.
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
(2021)
Article
Physiology
Catherine Fortier, Charles-Antoine Garneau, Mathilde Pare, Hasan Obeid, Nadege Cote, Karine Duval, Remi Goupil, Mohsen Agharazii
Summary: The acute administration of nitroglycerin leads to a significant reduction in pulse wave velocity of muscular arteries without affecting aortic pulse wave velocity. This results in an unfavorable change in the AB-PWV and AF-PWV ratios, potentially increasing pulse pressure transmission into the microcirculation.
FRONTIERS IN PHYSIOLOGY
(2021)
Review
Endocrinology & Metabolism
Ran Wei, Weihao Wang, Qi Pan, Lixin Guo
Summary: This systematic review and meta-analysis evaluated the effects of SGLT-2 inhibitors on endothelial function and arteriosclerosis in diabetic patients. The results showed that SGLT-2 inhibitors significantly improved endothelial function, but had no significant effect on arteriosclerosis levels.
FRONTIERS IN ENDOCRINOLOGY
(2022)
Article
Pharmacology & Pharmacy
Che-Wei Liao, Yen-Tin Lin, Cheng-Hsuan Tsai, Yi-Yao Chang, Zheng-Wei Chen, Ching-Chu Lu, Chien-Ting Pan, Chin-Chen Chang, Bo-Ching Lee, Yu-Wei Chiu, Wei-Chieh Huang, Kuo-How Huang, Tai-Shuan Lai, Chi-Shen Hung, Vin-Cent Wu, Xue-Ming Wu, Yen-Hung Lin
Summary: This study aimed to evaluate the effect of mineralocorticoid receptor antagonists (MRAs) on arterial stiffness in patients with primary aldosteronism (PA) and compare it with surgical treatment. The results showed no significant differences in the improvement of arterial stiffness between the MRA treatment group and the surgical treatment group. This suggests that MRAs play an important role in improving arterial stiffness in PA patients.
THERAPEUTIC ADVANCES IN CHRONIC DISEASE
(2023)
Article
Cardiac & Cardiovascular Systems
Shuji Sato, Takuro Ito, Tsuyoshi Tabata, Akihiro Ogawa, Atsuhito Saiki, Kazuhiro Shimizu
Summary: After BPA, the mean pulmonary artery pressure and CAVI significantly decreased in CTEPH patients. Biventricular remodeling occurred, with a decrease in right ventricular area and an increase in left ventricular volume after BPA. Changes in CAVI were significantly correlated with changes in pulmonary arterial pressure and biventricular remodeling.
FRONTIERS IN CARDIOVASCULAR MEDICINE
(2023)
Article
Peripheral Vascular Disease
Rong Cao, Jianwei Yue, Ting Gao, Gang Sun, Xiaomin Yang
Summary: This study aimed to analyze the relationship between brachial-ankle pulse wave velocity (b-a PWV) and the white coat effect (WCE). The findings showed a positive correlation between high WCE and arterial stiffness. This association was confirmed in subgroup analysis. The research results are important for further understanding of WCE and target organ damage.
JOURNAL OF CLINICAL HYPERTENSION
(2022)
Article
Cardiac & Cardiovascular Systems
Jaroslaw Krolczyk, Anna Skalska, Karolina Piotrowicz, Malgorzata Mossakowska, Tomasz Grodzicki, Jerzy Gasowski
Summary: The ankle-brachial index (ABI) is associated with long-term mortality risk in older individuals, particularly when ABI is less than 0.9. In the 80 years and older age group, mortality is mainly influenced by age and IL-6 levels, rather than ABI.
Review
Environmental Sciences
Karolina Piotrowicz, Alicja Klich-Raczka, Anna Skalska, Barbara Gryglewska, Tomasz Grodzicki, Jerzy Gasowski
Summary: This study conducted a systematic review and meta-analysis to explore the relationship between pulse wave velocity (PWV) and sarcopenia. The findings showed that sarcopenic individuals had higher PWV values and a greater probability of concurrent sarcopenia with higher PWV values. The study also suggested that increased stiffness of the aorta may be associated with sarcopenia and that sarcopenia could potentially accelerate age-related large arterial remodeling.
INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH
(2022)
Article
Geriatrics & Gerontology
Gulistan Bahat, Birkan Ilhan, Tugba Erdogan, Nezahat Muge Catikkas, Mehmet Akif Karan, Michael Drey, Jerzy Gasowski, Marina Kotsani, Karolina Piotrowicz, John Morley
Summary: Frailty is a common geriatric syndrome that indicates declining homeostasis and increased risk of disability and mortality. The Simplified Modified Fried Frailty Scale is a practical screening tool that can be adapted and validated in different European languages.
EXPERIMENTAL GERONTOLOGY
(2022)
Article
Geriatrics & Gerontology
Karolina Piotrowicz, Monika Rys, Ian Perera, Barbara Gryglewska, Malgorzata Fedyk-Lukasik, Jean-Pierre Michel, Barbara Wizner, Wojciech Sydor, Agnieszka Olszanecka, Tomasz Grodzicki, Jerzy Gasowski
Summary: In COVID-19, the assessment of muscle atrophy and frailty in elderly patients is associated with predicting survival and length of hospital stay. This assessment may also be valuable in other acute severe infections.
Editorial Material
Medicine, General & Internal
Leonardo Bencivenga, Karolina Piotrowicz
FRONTIERS IN MEDICINE
(2023)
Review
Psychiatry
Anna Rudzinska, Ian Perera, Barbara Gryglewska, Jerzy Gasowski, Karolina Piotrowicz
Summary: A significant number of individuals aged 75 and above experience major depression. Symptoms of depression in elderly patients are often overlooked or misdiagnosed as a natural part of aging. This study explores the potential benefits of adhering to the Mediterranean diet in preventing and alleviating depressive symptoms among the elderly. The review of 9 studies indicates that adherence to the principles of the Mediterranean diet may have a positive impact on the mental well-being of elderly patients and encourages further research on the relationship between this diet and depression.
PSYCHIATRIA POLSKA
(2023)
Review
Nutrition & Dietetics
Anna Rudzinska, Karolina Piotrowicz, Ian Perera, Barbara Gryglewska, Jerzy Gasowski
Summary: Anorexia of aging is a common problem in older adults, with prevalence ranging from 10% to over 30% depending on the setting. This systematic review found a weighted total prevalence of 11.3% for anorexia of aging among community-dwelling older adults. Frailty or risk of frailty was associated with a higher prevalence of anorexia of aging. More research is needed to understand the direction of this relationship.
Article
Medicine, General & Internal
Karolina Piotrowicz, Ian Perera, Monika Rys, Anna Skalska, Suzy V. Hope, Barbara Gryglewska, Jean-Pierre Michel, Tomasz Grodzicki, Jerzy Gasowski
Summary: This study examined the impact of acute viral respiratory infections, including COVID-19, on the physical activity of hospitalized older patients. The results showed that COVID-19 status did not significantly affect physical activity. It was also found that muscular function upon admission was associated with physical activity.
JOURNAL OF CLINICAL MEDICINE
(2023)
Article
Geriatrics & Gerontology
Karolina Piotrowicz, Hanna Kujawska-Danecka, Kacper Jagiello, Adam Hajduk, Anna Skalska, Malgorzata Mossakowska, Tomasz Zdrojewski, Tomasz Grodzicki, Jerzy Gasowski
Summary: This study conducted a survey among older Poles and found that slow gait speed is the predominant component of frailty. Among older adults, at least 72% have at least one frailty component. The overall prevalence of frailty is 15.9% and pre-frailty is 55.8%.
AGING CLINICAL AND EXPERIMENTAL RESEARCH
(2023)
Article
Primary Health Care
Anna Pacholek, Karolina Piotrowicz, Jerzy Gasowski, Tomasz Tomasik
Summary: This study found that caregivers' assessment of older patients can be a valuable source of information and helpful in diagnosing important health issues. However, caregivers have difficulties when asked to assess depression and insomnia in the older adults they care for, and their answers do not always correspond with the actual assessment results. General practitioners should pay more attention to the needs of caregivers themselves and provide them with necessary knowledge about caring for older people.
Correction
Geriatrics & Gerontology
K. Piotrowicz, M. Rzeznik, B. Gryglewska, T. Grodzicki, J. Gasowski
LANCET HEALTHY LONGEVITY
(2022)