Hesperetin derivative-16 attenuates CCl4-induced inflammation and liver fibrosis by activating AMPK/SIRT3 pathway

Platycodin D alleviates liver fibrosis and activation of hepatic stellate cells by regulating JNK/c-JUN signal pathway

(2020) Yong-mei Liu et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Epigenetic silencing of LncRNA ANRIL enhances liver fibrosis and HSC activation through activating AMPK pathway

(2020) Jing‐Jing Yang et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

SIRT1 and aging related signaling pathways

(2020) Cui Chen et al.   MECHANISMS OF AGEING AND DEVELOPMENT

The Roles of Mitochondrial SIRT4 in Cellular Metabolism

(2019) Zheying Min et al.   Frontiers in Endocrinology

AMPK agonist AICAR ameliorates portal hypertension and liver cirrhosis via NO pathway in the BDL rat model

(2019) Liangshuo Hu et al.   JOURNAL OF MOLECULAR MEDICINE-JMM

Inflammatory pathways in alcoholic steatohepatitis

(2019) Bin Gao et al.   JOURNAL OF HEPATOLOGY

Berberine alleviates nonalcoholic fatty liver induced by a high-fat diet in mice by activating SIRT3

(2019) Xi Xu et al.   FASEB JOURNAL

Downregulation of sirtuin 3 by palmitic acid increases the oxidative stress, impairment of mitochondrial function, and apoptosis in liver cells

(2019) Garima Sharma et al.   JOURNAL OF BIOCHEMICAL AND MOLECULAR TOXICOLOGY

SIRT1 protects cochlear hair cell and delays age-related hearing loss via autophagy

(2019) Jiaqi Pang et al.   NEUROBIOLOGY OF AGING

SIRT7 mediates L1 elements transcriptional repression and their association with the nuclear lamina

(2019) Berta N Vazquez et al.   NUCLEIC ACIDS RESEARCH

SIRT2: Controversy and multiple roles in disease and physiology

(2019) Yan Wang et al.   AGEING RESEARCH REVIEWS

Wogonin attenuates liver fibrosis via regulating hepatic stellate cell activation and apoptosis

(2019) Xiao-Sa Du et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Hesperetin derivative attenuates CCl4-induced hepatic fibrosis and inflammation by Gli-1-dependent mechanisms

(2019) Xin Chen et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Celastrol exerts anti‐inflammatory effect in liver fibrosis via activation of AMPK‐SIRT3 signalling

(2019) Yuqin Wang et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Low-Level Saturated Fatty Acid Palmitate Benefits Liver Cells by Boosting Mitochondrial Metabolism via CDK1-SIRT3-CPT2 Cascade

(2019) Lin Liu et al.   DEVELOPMENTAL CELL

Naringenin attenuates the progression of liver fibrosis via inactivation of hepatic stellate cells and profibrogenic pathways

(2019) Erika Hernández-Aquino et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Dihydromyricetin Ameliorates Nonalcoholic Fatty Liver Disease by Improving Mitochondrial Respiratory Capacity and Redox Homeostasis Through Modulation of SIRT3 Signaling

(2018) Xianglong Zeng et al.   ANTIOXIDANTS & REDOX SIGNALING

Autophagy inhibition attenuates the induction of anti-inflammatory effect of catalpol in liver fibrosis

(2018) Zhaoguo Liu et al.   BIOMEDICINE & PHARMACOTHERAPY

Functions of the sirtuin deacylase SIRT5 in normal physiology and pathobiology

(2018) Surinder Kumar et al.   CRITICAL REVIEWS IN BIOCHEMISTRY AND MOLECULAR BIOLOGY

Diabetes, plasma glucose and incidence of fatty liver, cirrhosis and liver cancer: A prospective study of 0.5 million people

(2018) Yuanjie Pang et al.   HEPATOLOGY

Design, synthesis and investigation of potential anti-inflammatory activity of O-alkyl and O-benzyl hesperetin derivatives

(2018) Ai-Ling Huang et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

SENP2 alleviates CCl 4 -induced liver fibrosis by promoting activated hepatic stellate cell apoptosis and reversion

(2018) Fang-Tian Bu et al.   TOXICOLOGY LETTERS

Liver fibrosis

(2018) M. Merve Aydin et al.   Turkish Journal of Gastroenterology

Therapeutic effect of Sirtuin 3 on ameliorating nonalcoholic fatty liver disease: The role of the ERK-CREB pathway and Bnip3-mediated mitophagy

(2018) Ruibing Li et al.   Redox Biology

Anthocyanins isolated from blueberry ameliorates CCl4 induced liver fibrosis by modulation of oxidative stress, inflammation and stellate cell activation in mice

(2018) Jianchao Sun et al.   FOOD AND CHEMICAL TOXICOLOGY

γ-Mangostin alleviates liver fibrosis through Sirtuin 3-superoxide-high mobility group box 1 signaling axis

(2018) Anqi Wang et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Hesperitin derivative-11 suppress hepatic stellate cell activation and proliferation by targeting PTEN/AKT pathway

(2017) Wan-xia Li et al.   TOXICOLOGY

Hesperetin derivative-14 alleviates inflammation by activating PPAR-γ in mice with CCl 4 -induced acute liver injury and LPS-treated RAW264.7 cells

(2017) Xin Chen et al.   TOXICOLOGY LETTERS

AMPK: a novel target for treating hepatic fibrosis

(2017) Zhenxing Liang et al.   Oncotarget

Reversal of liver cirrhosis: current evidence and expectations

(2017) Young Kul Jung et al.   KOREAN JOURNAL OF INTERNAL MEDICINE

The characteristics of activated portal fibroblasts/myofibroblasts in liver fibrosis

(2016) Daniel Karin et al.   DIFFERENTIATION

New Developments on the Treatment of Liver Fibrosis

(2016) Yukinori Koyama et al.   DIGESTIVE DISEASES

Cucurbitacin E ameliorates hepatic fibrosis in vivo and in vitro through activation of AMPK and blocking mTOR-dependent signaling pathway

(2016) Yan-Ling Wu et al.   TOXICOLOGY LETTERS

Sirtuin regulation in aging and injury

(2015) Ninu Poulose et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Sirtuins: Nodes Connecting Aging, Metabolism and Tumorigenesis

(2014) Yisha Yao et al.   CURRENT PHARMACEUTICAL DESIGN

Sirtuins Family- Recent Development as a Drug Target for Aging, Metabolism, and Age Related Diseases

(2013) Chiranjib Chakraborty et al.   CURRENT DRUG TARGETS

Long-term entecavir therapy results in the reversal of fibrosis/cirrhosis and continued histological improvement in patients with chronic hepatitis B

(2010) Ting-Tsung Chang et al.   HEPATOLOGY