4.3 Article

A comprehensive epidemiological study of rosacea in Germany

期刊

EUROPEAN JOURNAL OF DERMATOLOGY
卷 31, 期 6, 页码 744-751

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JOHN LIBBEY EUROTEXT LTD
DOI: 10.1684/ejd.2021.4165

关键词

rosacea; epidemiology; therapeutic outcome; epidemiologic study; symptoms; therapy

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This study aimed to provide an updated perspective on the epidemiology of rosacea in Germany. Findings showed a high prevalence of clinical features reported by patients but often underdiagnosed by physicians, with temperature and UV radiation identified as common triggers. Disease-related quality of life was found to decrease with the number of prescribed drugs and uncontrolled symptom activity, especially affecting female patients.
Background: Rosacea is one of the most common skin diseases causing great distress in affected patients. For optimal patient care, epidemiological studies on disease distribution and clinical aspects are essential. Objectives: The goal of this study was to provide an updated perspective on the current state of rosacea epidemiology in Germany. Materials & Methods: A cohort of 777 rosacea patients was assessed based on a detailed online questionnaire. Information regarding patients' demographics, course and clinical presentation of rosacea, trigger factors, dermatological consultations, treatment adherence and satisfaction as well as quality of life were obtained. Results: There was a very high self-reported prevalence of primary and secondary rosacea features (flushing: n = 726, 93.4%; papules/pustules: n = 613, 79.0%; telangiectasia: n = 590, 75.9%; subjective symptoms: n = 691, 88.9%). However, these clinical findings were often underdiagnosed by the treating physicians, while changes in temperature and ultraviolet radiation were potent triggers across all patients (86.3%, 77.7%, respectively). Disease-related quality of life decreased with the number of drugs prescribed as well as with uncontrolled symptom activity, and was reduced in female patients. Conclusion: This study is the largest German-based assessment exclusively focusing on rosacea patients covering a variety of clinical aspects to optimize patient care.

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