Article
Medicine, General & Internal
Bartosz Zuchowski, Krzysztof Blaszyk, Jaroslaw Piskorski, Andrzej Wykretowicz, Przemyslaw Guzik
Summary: This study investigated the relationship between the atrioventricular conduction time and its components, the atrioventricular node and the His-Purkinje system, as well as the sex differences in these intervals. The results showed that the atrioventricular conduction time mainly depends on the conduction through the atrioventricular node, with less influence from the His-Purkinje system. These relationships are similar in both sexes, although men have longer conduction times through the atrioventricular node, His-Purkinje system, and total atrioventricular conduction time.
JOURNAL OF CLINICAL MEDICINE
(2023)
Article
Cardiac & Cardiovascular Systems
Alwin Zweerink, Elise Bakelants, Carine Stettler, Haran Burri
Summary: This study compared the procedural characteristics and outcomes of cryoablation and radiofrequency ablation for AVN ablation in patients with HBP. Cryoablation did not show any advantage over RFA and tended to require more redo procedures. Maintaining a distance of >= 6 mm from the His lead tip is recommended to avoid a rise in capture thresholds.
Article
Cardiac & Cardiovascular Systems
Tadej Zlahtic, Misa Fister, Peter Radsel, Marko Noc, Matjaz Sinkovec, David Zizek
Summary: Tachycardia-induced cardiomyopathy (T-CMP) related to supraventricular arrhythmia is a rare cause of refractory cardiogenic shock. His bundle pacing in conjunction with AVNA can be a successful treatment in such cases.
FRONTIERS IN CARDIOVASCULAR MEDICINE
(2022)
Article
Cardiac & Cardiovascular Systems
Chengming Ma, Wenwen Li, Yongmei Cha, Yunlong Xia, Lianjun Gao, Yingxue Dong
Summary: This article reports a case of a 70-year-old male with severe valvular cardiomyopathy, permanent atrial fibrillation, and slow ventricular response, who was admitted for severe heart failure and recurrent presyncope. Coronary computed tomography angiography showed enlarged atriums. His bundle pacing was attempted and a Wenckebach phenomenon was observed, which has not been previously reported in a patient with persistent atrial fibrillation. The enlarged atrium may have facilitated AV node capture. After the procedure, the atrium diameter decreased significantly and symptoms improved.
JOURNAL OF CARDIOVASCULAR DEVELOPMENT AND DISEASE
(2022)
Article
Cardiac & Cardiovascular Systems
Pugazhendhi Vijayaraman, Neil Patel, Shaun Colburn, Dominik Beer, Angela Naperkowski, Faiz A. Subzposh
Summary: This study aimed to assess the safety and feasibility of His-Purkinje conduction system pacing (HPCSP) in patients with atrioventricular block (AVB) and to describe the site of conduction block. HPCSP was successful in 97% of patients with AVB, and HBP and LBBAP were complementary in achieving stable and low capture thresholds.
JACC-CLINICAL ELECTROPHYSIOLOGY
(2022)
Review
Cardiac & Cardiovascular Systems
Ioanna Koniari, Andreas Gerakaris, Nicholas Kounis, Dimitrios Velissaris, Archana Rao, Mark Ainslie, Ahmed Adlan, Panagiotis Plotas, Ignatios Ikonomidis, Virginia Mplani, Ming-Yow Hung, Cesare de Gregorio, Theofilos Kolettis, Dhiraj Gupta
Summary: This review examines the literature on the use of atrioventricular node ablation and pacing in heart failure and atrial fibrillation patients. It shows that this strategy improves symptoms and cardiac performance, but may have complications such as worsening heart failure, arrhythmias, and sudden death. Cardiac resynchronization therapy is the optimal treatment, while His bundle pacing and left bundle branch pacing are potential alternatives.
JOURNAL OF CARDIOVASCULAR DEVELOPMENT AND DISEASE
(2023)
Review
Cardiac & Cardiovascular Systems
Yue Zhang, Yuan Jia, Jia Liu, Rongpin Du
Summary: In this study, the efficacy and safety of His bundle pacing (HBP) and Left bundle branch pacing (LBBP) were compared with right ventricular pacing (RVP) in patients with atrioventricular block (AVB). The results showed that compared to RVP, HBP and LBBP were superior in terms of paced QRS duration and preservation of left ventricular ejection fraction (LVEF). LBBP was associated with a lower pacing threshold and a greater R-wave amplitude compared to HBP, but the stability of pacing output may be a concern.
FRONTIERS IN CARDIOVASCULAR MEDICINE
(2022)
Article
Cardiac & Cardiovascular Systems
Zhiyong Qian, Siyuan Xue, Fengwei Zou, Chaotong Qin, Yao Wang, Xinwei Zhang, Yuanhao Qiu, Hongping Wu, Xiaofeng Hou, Jiangang Zou
Summary: The study aimed to develop a new personalized intraoperative criterion to confirm left bundle branch capture in patients with or without heart failure, which is of great significance.
Article
Cardiac & Cardiovascular Systems
David Zizek, Bor Antolic, Anja Zupan Meznar, Dinko Zavrl-Dzananovic, Matevz Jan, Jernej Stublar, Andrej Pernat
Summary: This study compared the short-term outcomes of HBP and BiV pacing in symptomatic atrial fibrillation patients and found that HBP was superior in post-implant QRS duration, LV volumes, and LVEF compared to BiV pacing. However, both groups showed similar improvement in NYHA class.
Article
Cardiac & Cardiovascular Systems
Daniel Rodriguez Munoz, Maria Generosa Crespo-Leiro, Ignacio Fernandez Lozano, Jose Luis Zamorano Gomez, Rafael Peinado Peinado, Luis Manzano Espinosa, Javier de Juan Baguda, Alvaro Marco del Castillo, Fernando Arribas Ynsaurriaga, Rafael Salguero Bodes
Summary: This study aims to explore the long-term benefits and safety profile of heart rate regularization through left-bundle branch pacing (LBBP) and atrioventricular node ablation (AVNA) compared with pharmacological rate-control strategy in patients with heart failure and permanent atrial fibrillation. The study will be conducted from March 2022 to February 2027, with 334 patients enrolled and followed up for a minimum of 36 months. The primary outcome measure is the composite of all-cause mortality, heart failure hospitalization, and worsening heart failure at 36 months.
Article
Cardiac & Cardiovascular Systems
Kazumasa Suga, Hiroyuki Kato, Yasuya Inden, Satoshi Yanagisawa, Hisashi Murakami, Kenji Kada, Naoya Tsuboi, Toyoaki Murohara
Summary: This study assessed the efficacy and feasibility of His-bundle pacing (HBP) implantation guided by a distal His-bundle electrogram (HBE) approach in patients with atrioventricular block. The results showed a significantly higher detection rate of distal HBE in successful HBP patients compared to the failure group.
PACE-PACING AND CLINICAL ELECTROPHYSIOLOGY
(2021)
Article
Cardiac & Cardiovascular Systems
Michael C. Y. Nam, Patricia O'Sullivan, Ivaylo Tonchev, Benjamin M. M. Moore, Troy Watts, Gareth Wynn, Geoff Lee, Subodh Joshi, Irene Stevenson
Summary: To compare long-term pacing parameters, a case series used His bundle pacing (HBP) combined with deep septal left bundle branch area pacing (dsLBBAP) in patients with treatment-refractory atrial fibrillation. The results showed that HBP had lower sensed ventricular amplitude and lead impedance compared to dsLBBAP, but had a shorter paced QRS duration.
JOURNAL OF ARRHYTHMIA
(2023)
Article
Cardiac & Cardiovascular Systems
Fu Guan, Ardan M. Saguner, Daniel Hofer, Thomas Wolber, Alexander Breitenstein, Nazmi Krasniqi, Urs Eriksson, Jan Steffel, Corinna Brunckhorst, Firat Duru
Summary: This study aimed to investigate the characteristics of His bundle potentials in patients with symptomatic atrioventricular nodal reentrant tachycardia (AVNRT) and to determine whether they can provide clues for the identification of slow pathway (SP). The study found that the amplitude and duration of HBmax were higher and longer, respectively, in patients with AVNRT compared to those with atrioventricular reentrant tachycardia (AVRT).
CARDIOLOGY JOURNAL
(2023)
Article
Cardiac & Cardiovascular Systems
Ajay Pillai, Jeffrey Kolominsky, Jayanthi N. Koneru, Jordana Kron, Richard K. Shepard, Gautham Kalahasty, Weijian Huang, Atul Verma, Kenneth A. Ellenbogen
Summary: AVJA with left bundle branch area pacing (LBBAP) leads shows a higher success rate and fewer lead-related complications.
Article
Cardiac & Cardiovascular Systems
Maja Ivanovski, Miha Mrak, Anja Zupan Meznar, David Zizek
Summary: Conduction system pacing (CSP) modalities, including His-bundle pacing (HBP) and left bundle branch pacing (LBBP), showed superior symptomatic and echocardiographic improvement compared to biventricular (BiV) pacing in heart failure patients.
JOURNAL OF CARDIOVASCULAR DEVELOPMENT AND DISEASE
(2022)
Article
Cardiac & Cardiovascular Systems
Jacquelyn Kukulski, Jacqueline Rausa, Julia Weld, Amina Jaji, Nobuyuki Ikeda, Brian Lee, Lisha Thomas, Robert H. Anderson, Rohit S. Loomba
Summary: This study demonstrates that a structured, interactive teaching session using heart specimens can effectively educate paediatric residents on cardiac anatomy. The residents showed a strong interest in this type of session and achieved significant learning outcomes.
CARDIOLOGY IN THE YOUNG
(2023)
Article
Cardiac & Cardiovascular Systems
Tyler Bendrick, Dillon Polito, Randy Richardson, Robert H. Anderson, Deepa Prasad
Summary: In this study, we present a case series of six children with ligamentous atresia of the left side of a double arch assessed using CT, highlighting the importance of CT in accurate diagnosis and surgical planning.
CARDIOLOGY IN THE YOUNG
(2023)
Letter
Cardiac & Cardiovascular Systems
Robert H. Anderson
CARDIOLOGY IN THE YOUNG
(2023)
Article
Cardiac & Cardiovascular Systems
Julia Weld, Brian Lee, Rohit S. Loomba, Saad Siddiqui, Amina Jaji, Luca Vricella, Narutoshi Hibino, Robert H. Anderson, Chawki Elzein
Summary: This article presents a rare case of tricuspid atresia with common arterial trunk, accompanied by interrupted aortic arch. The patient underwent surgical treatment and was discharged at the age of two months.
CARDIOLOGY IN THE YOUNG
(2023)
Review
Cardiac & Cardiovascular Systems
Robert H. Anderson, Madalina Garbi, Dasa Zugwitz, Steffen E. Petersen, Robin Nijveldt
Summary: It is widely accepted that the mitral valve functions through a complex combination of different components. However, controversies still exist in the understanding and description of these components. It is important to accurately describe the valvar complex using appropriate terms and to utilize three-dimensional techniques for clinical imaging.
Article
Cardiac & Cardiovascular Systems
Rehan Mahmud, Eduardo Back Sternick, Damian Sanchez-Quintana, Yolanda Macias, Shakeel Muhammad Jamal, Beth Bailey, Ayush Mohan, Matthew T. Lee, Jenna E. Lee, Marcos Celio de Almeida, Robert H. Anderson
Summary: This study found that histologically specialised pathways connecting the branching component of the atrioventricular conduction axis with the crest of the muscular ventricular septum exist in about three-fourths of the histological datasets. By observing 34 patients undergoing His bundle pacing, it was found that the QRS complex closely resembled known conduction through fasciculo-ventricular pathways in 32 patients, with only two patients not showing a delta wave at any pacing voltages. Therefore, the conclusion was drawn that His bundle pacing can reveal fasciculo-ventricular pathways concealed during sinus rhythm.
Review
Anatomy & Morphology
Anthony Graham, Jill P. J. M. Hikspoors, Robert H. Anderson, Wouter H. Lamers, Simon D. Bamforth
Summary: The pharyngeal arches, bulges on the head of vertebrate embryos, have been traditionally labelled as 1, 2, 3, 4, and 6, with no fifth arch. Recent studies have shown that this labelling is problematic and causes confusion in understanding pharyngeal arch development. To address this, a new terminology is proposed, labelling the arches as mandibular, hyoid, carotid, aortic, and pulmonary.
JOURNAL OF ANATOMY
(2023)
Review
Cardiac & Cardiovascular Systems
Robert H. Anderson, Adrian Crucean, Diane E. Spicer
Summary: As yet, there is no agreed definition for the so-called hypoplastic left heart syndrome. Even its origin remains contentious. Our review summarizes the evidence supporting the notion that an intact ventricular septum should now be part of the definition of the hypoplastic left heart syndrome.
JOURNAL OF CARDIOVASCULAR DEVELOPMENT AND DISEASE
(2023)
Review
Cardiac & Cardiovascular Systems
Madan M. Maddali, Hamood N. Al Kindi, Pranav Subbaraya Kandachar, Abdulla Al Farqani, Khalid S. Al Alawi, Faiza Al Kindi, Salim Nasser Al-Maskari, Diane E. Spicer, Robert Henry Anderson
Summary: This article discusses the anomalous systemic venous connections, specifically the connection of the systemic venous tributaries to the left atrium. Previous studies were compromised by the inclusion of individuals with isomeric atrial appendages, leading to inaccurate descriptions. In most cases, the anomalous connections are associated with a sinus venosus defect. Rarely, the primary atrial septum can be located in a way that directly connects the systemic venous sinus to the left atrium instead of the right atrium. The report includes a series of cases potentially falling into the category of anomalous systemic venous connections, with a spectrum of partially to totally anomalous connections. One case is an autopsy example of a totally anomalous systemic venous connection caused by an abnormal location of the primary atrial septum. The article discusses the potential morphogenesis of this finding and emphasizes the distinction between anomalous systemic venous connections and anomalous systemic venous drainage.
WORLD JOURNAL FOR PEDIATRIC AND CONGENITAL HEART SURGERY
(2023)
Article
Cardiac & Cardiovascular Systems
Ujjwal Kumar Chowdhury, Robert H. Anderson, Niraj Nirmal Pandey, Niwin George, Lakshmi Kumari Sankhyan, Maroof A. Khan, Shikha Goja, Sivasubramanian Ramakrishnan, Saurabh Kumar Gupta
Summary: This study compares the long-term outcomes of biventricular, univentricular, and one-and-one-half ventricular repairs in patients with left and right isomerism. The results show that surgical correction in patients with right isomerism had higher mortality rates, indicating the need for reassessment of management strategies.
WORLD JOURNAL FOR PEDIATRIC AND CONGENITAL HEART SURGERY
(2023)
Review
Cardiac & Cardiovascular Systems
Ujjwal Kumar Chowdhury, Robert H. H. Anderson, Niraj Nirmal Pandey, Sundeep Mishra, Lakshmi Kumari Sankhyan, Niwin George, Maroof A. Khan, Shikha Goja
Summary: In this study, the indications, timing, and results of the one-and-a-half ventricle repair as an alternative surgical procedure to the Fontan circulation and high-risk biventricular repair were reviewed. The reported operative mortalities ranged from 3% to 20%, with a 10-year actuarial survival of 80% to 90%. The one-and-a-half ventricle repair reduces the surgical risk for biventricular repair and reverses the Fontan paradox.
CARDIOLOGY IN THE YOUNG
(2023)
Review
Anatomy & Morphology
Adrian Crucean, Diane E. Spicer, Justin T. Tretter, Timothy J. Mohun, Robert H. Anderson
Summary: Debates remain regarding the anatomy of the morphologically right ventricle, such as its evaluation in bipartite or tripartite fashion and the number of leaflets in the tricuspid valve. Resolving these controversies is crucial for understanding and treating congenital heart defects in children.
JOURNAL OF ANATOMY
(2023)
Review
Cardiac & Cardiovascular Systems
Hussam Ali, Pierpaolo Lupo, Sara Foresti, Guido De Ambroggi, Robert H. Anderson, Carmine De Lucia, Dario Turturiello, Edoardo Maria Paganini, Riccardo Bessi, Igino Contrafatto, Ahmad Abdelrady Abdelsalam Farghaly, Ernesto Cristiano, Riccardo Cappato
Summary: Due to its endocardial course, the right bundle branch (RBB) is susceptible to traumatic block caused by bumping during right-heart catheterization. Catheter-induced RBB block (CI-RBBB) has become a common phenomenon in cardiac electrophysiology, but it is often overlooked by electrophysiologists. CI-RBBB can provide valuable diagnostic information, but may occasionally lead to diagnostic difficulties or undesired consequences. This article aims to provide a comprehensive practical review of CI-RBBB and its impact on the conduction system and various arrhythmic substrates.
JOURNAL OF CARDIOVASCULAR ELECTROPHYSIOLOGY
(2023)
Review
Cardiac & Cardiovascular Systems
Robert H. Anderson, Diane E. Spicer, Colin J. Mcmahon, R. Krishna Kumar, Justin T. Tretter
Summary: Surgical repair of ventricular channels is improved with precise placement of a patch or baffle. Communication between surgeons and cardiologists is important. Currently, the same term is used for different areas within the heart.
CARDIOLOGY IN THE YOUNG
(2023)
Article
Anatomy & Morphology
Robert H. Anderson, Wouter H. Lamers, Jill P. J. M. Hikspoors, Timothy J. Mohun, Simon D. Bamforth, Bill Chaudhry, Lorraine Eley, Janet Kerwin, Moira Crosier, Deborah J. Henderson
Summary: The separation of the outflow tract of the developing heart into the systemic and pulmonary arterial channels is still controversial and not well understood. This study investigates the anatomical changes and developmental processes involved in the separation of the outflow channels, using histological and high-resolution imaging techniques. The findings provide insights into the development of the tripartite postnatal arrangement.
JOURNAL OF ANATOMY
(2023)