Effects on reproductive, biochemical and genotoxic parameters of herbicides 2,4-D and glyphosate in silver catfish (Rhamdia quelen)

The objective of this work was to evaluate the effects of the herbicides 2,4-D, glyphosate and the mixture of both on oxidative stress, genotoxicity and the rates of fertilization, hatching and larval normality in silver catfish. Exposure to glyphosate and the mixture of herbicides significantly decreased the fertilization of oocytes and the hatching of eggs. The different concentrations of 2,4-D and glyphosate, in addition to the mixture of both, did not affect the rates of larval normality, the activity of CAT, GST, LPO, and PCO. SOD activity was not evident in any of the treatments. Exposure to 2,4-D and the mixture of herbicides caused damage to the genetic material of larvae silver catfish. Our results show that although high concentrations of the herbicides were used, changes caused by them were detected in only some of the tested biomarkers.

Automated summary

This study evaluated the effects of 2,4-D, glyphosate, and their mixture on oxidative stress, genotoxicity, and the rates of fertilization, hatching, and larval normality in silver catfish. The results showed that glyphosate and the mixture significantly decreased fertilization and hatching, while 2,4-D and the mixture caused genetic damage to the larvae.