Article
Environmental Sciences
Yu Zhang, Weifeng Tang, Yuqing Wang, Min Nian, Fan Jiang, Jun Zhang, Qian Chen
Summary: School-age children in Shanghai were widely exposed to antibiotics, and unhealthy diet was associated with a higher level of antibiotic exposure. There were significant differences in antibiotic exposure rates between urban and suburban children.
SCIENCE OF THE TOTAL ENVIRONMENT
(2022)
Article
Environmental Sciences
Baolin Wang, Menglong Geng, Mengdie Li, Xiaorui Wang, Hong Gan, Ying Tang, Qianhui Yang, Yuwei Liu, Xinliu Yang, Sheng Wang, Kaiyong Liu, Zhaolian Wei, Shanshan Shao, Peng Zhu, Yunxia Cao, Fangbiao Tao
Summary: This study investigated the preconception exposure to antibiotics among childbearing couples in Anhui and found that nearly 98% of the couples had environmental exposure to antibiotics. More than 8% of the couples had health risks due to antibiotic exposure. Several potential determinants of urinary antibiotics deserve more attention in future research.
ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY
(2023)
Article
Engineering, Environmental
Yuanping Wang, Xiaolian Dong, Minghui Han, Zichen Yang, Yi Wang, Lu Qian, Min Huang, Baozhang Luo, Hexing Wang, Yue Chen, Qingwu Jiang
Summary: This study collected 94 honey samples from the Chinese market and assessed the presence of 20 common antibiotics and their potential health risks. The results showed widespread antibiotic residues in Chinese honey, which varied with production place, sale price, and commercial category of nectariferous plants, but posed a low health risk.
JOURNAL OF HAZARDOUS MATERIALS
(2022)
Article
Environmental Sciences
Sandra Perez, Catherine German-Labaume, Sebastien Mathiot, Sylvaine Goix, Philippe Chamaret
Summary: The study investigated the potential relationships between air pollution, socio-economy, and proven pathologies within an industrial area in Southern France, highlighting correlations between population exposure to air pollutants and some pathologies. Specific health effects were observed for different pollutants at different concentration levels, while the influence of socio-economic factors on diseases was also revealed. Additionally, a diffuse PCB pollution was observed in the study area which may potentially cause lung cancers.
ENVIRONMENTAL RESEARCH
(2022)
Article
Environmental Sciences
Jianlin Chen, Liangliang Huang, Qian Wang, Honghu Zeng, Jun Xu, Zhongbing Chen
Summary: This study investigated the occurrence and distribution of seven antibiotics in aquaculture areas in Guilin, South of China, revealing relatively low concentrations of antibiotics but potential risks to microorganisms and organic matter in water and sediment. The results suggest that antibiotics may not pose a direct risk to human health via dietary exposure, but could lead to secondary pollution in sediments, thus requiring heightened local management awareness.
ENVIRONMENTAL RESEARCH
(2022)
Article
Biochemistry & Molecular Biology
Huimin Jin, Siyan Che, Kunfu Wu, Miaomiao Wu
Summary: This study found that ellagic acid (EA) has the potential to replace antibiotics to prevent microbial-mediated immune responses and alleviate inflammation caused by intestinal stress. EA preprocessing reduced the abundance of Streptococcus in the gut, modulated the distribution of intestinal lymphocytes, reduced the frequency of specific cells, and alleviated the upward migration of cells to the apex of the intestinal villi.
Article
Engineering, Environmental
Aimee K. Murray, Isobel Stanton, William H. Gaze, Jason Snape
Summary: Antibiotics and antimicrobials are widely used, misused and overused in human and veterinary medicine, animal husbandry and aquaculture, potentially leading to the enrichment of antimicrobial resistant bacteria in the environment. There is a need to develop a new methodology for environmental risk assessment to ensure that diffuse and point source discharges are safe choices.
Review
Environmental Sciences
Jiagen Geng, Xiaoying Liu, Jie Wang, Si Li
Summary: The presence of antibiotics in farmland soil is a potential threat to food safety. This review assessed the bioaccumulation potential of antibiotics in edible vegetables and crops grown under realistic farming scenarios and evaluated the associated human health risk. The study found that tetracyclines exhibited higher residue levels in plants compared to other classes of antibiotics, possibly due to their higher concentrations in soils and greater bioconcentration factors. Antibiotics were more likely to accumulate in greenhouse-grown plants compared to those grown in open fields. Risk assessment indicated that daily consumption of antibiotic-contaminated vegetables and food crops did not pose a major health risk.
SCIENCE OF THE TOTAL ENVIRONMENT
(2022)
Article
Environmental Sciences
Yuan Zhang, Ziquan Lv, Xiaowei Li, Kunxia Zhao, Suli Huang, Yuhua Chen, Yulin Fu, Changfeng Peng, Tingting Cao, Yuebin Ke, Xi Xia
Summary: The occurrence of antibiotics in the feces of elderly individuals in Shenzhen, China, was investigated. 18 compounds belonging to 5 classes of antibiotics were identified in 74 of 140 fecal samples. Animal products collected from local markets also showed antibiotic residues, with strong correlations to the human fecal samples.
ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH
(2023)
Article
Engineering, Environmental
Yingying Wang, Xiaolian Dong, Jinxin Zang, Xinping Zhao, Feng Jiang, Lufang Jiang, Chenglong Xiong, Na Wang, Chaowei Fu
Summary: Trace levels of antibiotics were found in tap water and well water in two rural residential areas in Eastern China, primarily consisting of macrolides and sulfonamides. While the health risk of exposure to antibiotics through drinking-water was low, long-term exposure patterns to low-dose antibiotics should not be ignored.
Article
Environmental Sciences
Yibo Zhang, Ming Li, Fang Chang, Malan Yi, Hongmei Ge, Jie Fu, Chenyuan Dang
Summary: This study investigates the differences in responses between cyanobacteria and green algae, which are the recommended test organisms for toxicity assessments, to the same chemical. The results show that these two species have different resistance mechanisms and can alleviate the toxicity of sulfamethoxazole through different pathways. Inconsistent assessment results for antibiotics using cyanobacteria and green algae are likely due to their different resistance mechanisms. Improved indicators or comprehensive assessment methods should be considered for environmental toxicity assessments.
SCIENCE OF THE TOTAL ENVIRONMENT
(2023)
Article
Environmental Sciences
Chuleemas Boonthai Iwai, Theingi Khaung, Jarupong Prasopsuk, Balasubramani Ravindran
Summary: Inle Lake in Myanmar is an important freshwater biodiversity hotspot, but poor management of floating gardens has resulted in contamination of water and sediment with excessive nutrients and chemical residues. This study aims to assess the environmental risk to the lake ecosystem by investigating nutrient contamination in water and sediment, as well as pesticide residues in fish. The results show that non-GAP farming methods have higher levels of pesticide and nutrient contamination compared to GAP methods, posing potential threats to the lake ecosystem.
Article
Agriculture, Dairy & Animal Science
Xin Zhu, Yinhang Zhang, Yingzhuo Zhao, Lijuan Tao, Haiying Liu, Weiguo Dong, Guiqin Yang, Lin Li
Summary: The study found that dietary supplementation of 0.4% itaconic acid (IA) can improve nutrient digestibility, slaughter performance, antioxidant ability, and intestinal morphology of broiler chickens.
Review
Agriculture, Dairy & Animal Science
Shuo Yang, Xiaoqing Xu, Qing Peng, Lan Ma, Yu Qiao, Bo Shi
Summary: The over-use or misuse of antibiotics in livestock and poultry production has led to a rising threat of antibiotic resistance in animals and negative ecological effects. Exopolysaccharides from lactic acid bacteria (LAB-EPS) have been found to have anti-inflammatory and antimicrobial activities, and can regulate intestinal health and the immune system in livestock. LAB-EPS are considered as ideal alternatives to antibiotics due to their biodegradability, non-toxicity, and bio-compatibility.
Article
Environmental Sciences
Xin Zhang, Chaoyu Li, Dongdong Yao, Xiaojin Hu, Huijun Xie, Zhen Hu, Shuang Liang, Jian Zhang
Summary: Constructed wetlands using Fe and Mn ores as substrates showed high removal rates of antibiotics SMX and TMP, but also had potential negative effects and varied environmental risks. Fe ore had the lowest abundance of ARGs, indicating a reduced transmission risk. Mn ore initially inhibited growth and then promoted it. These findings provide insights for wetland health assessment and substrate selection.
ENVIRONMENTAL RESEARCH
(2024)
Article
Plant Sciences
Xin-Xin Zhao, Juan-Juan Chang, Qi-Lin Wang, Rong Lu, Ling-Jun Li, Xiao Sun, Wei-Dong Xie, Xia Li
JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH
(2016)
Article
Biochemistry & Molecular Biology
Chao Guo, Fangyuan Liu, Jie Qi, Jiahui Ma, Shiqi Lin, Caiyun Zhang, Qian Zhang, Hangyu Zhang, Rong Lu, Xia Li
Article
Biochemical Research Methods
Rashim Singh, Rong Lu, Ming Hu
ANALYTICAL BIOCHEMISTRY
(2020)
Article
Pharmacology & Pharmacy
Fulong Man, Chen Meng, Yang Liu, Yuchen Wang, Yun Zhou, Jinqian Ma, Rong Lu
Summary: Extracellular vesicles from ginger (GDEVs) were shown to have potential as drug carriers with a good loading capacity, as demonstrated by their saucer-like shape, small particle size, and negative zeta potential. The absorption of GDEVs in the rat intestine was concentration-dependent, with the highest absorption in the duodenum, suggesting their potential in drug delivery systems and the importance of lipid solubility in enhancing their loading capacity.
Article
Biotechnology & Applied Microbiology
Hongbo Wang, Kuangqi Yan, Huaran Xing, Jingdi Chen, Rong Lu
Summary: HA microspheres synthesized from waste abalone shells showed high adsorption capacity for Cu2+ in wastewater, with a potential for environmental protection. Thermodynamic analysis indicated the removal process was spontaneous and exothermic.
ENVIRONMENTAL TECHNOLOGY & INNOVATION
(2021)
Article
Biochemistry & Molecular Biology
Zhihan Cao, Ping Li, Xuqian Cao, Xu Wang, Bin Liu, Shuwen He, Guang Gao, Rong Lu, Zhi-Hua Li
Summary: This study investigated the reproductive toxicity of TPT on marine rotifer using environmental concentrations. The results showed that TPT concentrations affected the population size, reproductive rate, and growth rate of the rotifers. Additionally, TPT exposure led to oxidative damage, delayed reproduction, and changes in phenotypic traits. Furthermore, the expression of a gene associated with reproduction was altered by TPT exposure.
COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY C-TOXICOLOGY & PHARMACOLOGY
(2022)
Review
Pharmacology & Pharmacy
Ying Cai, Luoxin Zhang, Youjian Zhang, Rong Lu
Summary: Inflammatory bowel disease (IBD) is a chronic recurrent intestinal disease with limited treatment options and potential side effects of conventional drugs. It is also associated with colitis-associated cancer (CAC). Plant-derived exosomes have been found to be able to target drug delivery to the intestine, showing great potential for the treatment of intestinal diseases.
Review
Pharmacology & Pharmacy
Rong Lu, Yun Zhou, Jinqian Ma, Yuchen Wang, Xiaoqing Miao
Summary: This review focuses on intestinal efflux transporters that actively transport drugs from the enterocytes to the intestinal lumen, leading to poor absorption of orally-administered drugs. Various functional amphiphilic excipients and inhibitors that can suppress efflux transporter activity are discussed with the aim of reversing intestinal drug efflux and improving oral drug absorption. Different strategies of reducing intestinal drug efflux and various nano-formulations for improving oral drug absorption by inhibiting intestinal drug efflux are explored.
Review
Chemistry, Medicinal
Jinqian Ma, Yuchen Wang, Rong Lu
Summary: This paper reviewed the mechanisms and applications of chitosan and its derivatives in transdermal drug delivery. The permeation-promoting mechanisms, such as changing the structure of stratum corneum proteins and affecting intercellular lipids, were summarized. Various transdermal preparations containing chitosan and its derivatives, including nanoparticles and liposomes, were also discussed. Chitosan and its derivatives have excellent permeability-promoting property, good biocompatibility, and biodegradability, making them ideal materials for local transdermal drug delivery.
Review
Chemistry, Medicinal
Yuchen Wang, Junfeng Wang, Jinqian Ma, Yun Zhou, Rong Lu
Summary: Plant derived extracellular vesicles (EVs) are nano-sized membranous vesicles released by plant cells, which act as safe and effective drug carriers for the prevention and treatment of various diseases including inflammation, cancer, bacteria, and oxidative aging. This comprehensive review discusses the latest methods of isolating and characterizing plant derived EVs, as well as their applications in disease prevention, treatment, and drug delivery. The study also analyzes the potential clinical applications of plant derived EVs as drug carriers, and addresses the current challenges and considerations for their standardized use.
Correction
Pharmacology & Pharmacy
Fulong Man, Chen Meng, Yang Liu, Yuchen Wang, Yun Zhou, Jinqian Ma, Rong Lu
Article
Biochemistry & Molecular Biology
Xue-Li Zhao, Ping Li, Chunfeng Qu, Rong Lu, Zhi-Hua Li
Summary: This study evaluated the chronic toxicity of norfloxacin (NOR) on duckweed and found that NOR exposure led to concentration-dependent chlorosis, growth inhibition, and photosystem II inhibition. Reactive oxygen species (ROS) and osmotic regulatory substances content increased in response to NOR exposure, indicating oxidative stress and increased stress resistance. NOR exerts toxic effects on the aquatic plant Spirodela polyrrhiza.
COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY C-TOXICOLOGY & PHARMACOLOGY
(2022)
Review
Chemistry, Medicinal
Xiao-Ming Xi, Meng Chen, Shu-Jun Xia, Rong Lu
Summary: Exosomes, as bilayer membrane-coated extracellular vesicles, are natural carriers with low immunogenicity and high stability. Loading exogenous drugs into exosomes is essential for their use as drug carriers, and various techniques have been applied for drug loading, presenting both advantages and challenges.
Review
Nanoscience & Nanotechnology
Fulong Man, Junfeng Wang, Rong Lu
JOURNAL OF BIOMEDICAL NANOTECHNOLOGY
(2020)
Review
Environmental Sciences
Attila Csaba Kondor, Anna Viktoria Vancsik, Laszlo Bauer, Lili Szabo, Zoltan Szalai, Gergely Jakab, Gabor Maasz, Marta Pedrosa, Maria Jose Sampaio, Ana Rita Lado Ribeiro
Summary: This review provides a critical overview of research on the removal efficiency of priority substances and compounds of emerging concern through bank filtration, discussing influencing factors and future challenges. The findings show that the efficiency of bank filtration is influenced by multiple factors and varies for different substances.
ENVIRONMENTAL POLLUTION
(2024)
Article
Environmental Sciences
Xinyan Wang, Shuai Zhang, Huihui Yan, Zhao Ma, Yunshan Zhang, Haining Luo, Xueli Yang
Summary: This study investigated the association between ambient PM2.5, O3 pollution, and ovarian reserve in reproductive-aged Chinese women. The results showed that increased exposure to PM2.5 and O3 was associated with decreased AMH levels, indicating reduced ovarian reserve. Notably, the effects of O3 exposure on ovarian reserve were different from those of PM2.5 exposure.
ENVIRONMENTAL POLLUTION
(2024)
Article
Environmental Sciences
Tingting Ma, Yanjuan Ding, Fengjiao Xu, Chen Zhang, Min Zhou, Ya Tang, Yanrong Chen, Yating Wen, Rufei Chen, Bin Tang, Shigui Wang
Summary: The dragonfly species Orthetrum albistylum can accumulate heavy metals, and its heat shock protein genes have the potential to serve as biomarkers for monitoring environmental pollutants.
ENVIRONMENTAL POLLUTION
(2024)
Article
Environmental Sciences
Naoto Ishiwaka, Koya Hashimoto, Masayoshi K. Hiraiwa, Francisco Sanchez-Bayo, Taku Kadoya, Daisuke Hayasaka
Summary: Systemic insecticides and rising temperatures have combined effects on the abundance of Odonata nymphs in paddy fields. The standalone effect of insecticide exposure decreased the Odonata community, while nymphs decreased synergistically with temperature rise in paddy water. However, the impacts of each stressor alone varied among species.
ENVIRONMENTAL POLLUTION
(2024)
Article
Environmental Sciences
Marco Vecchiato, Carlo Barbante, Elena Barbaro, Francois Burgay, Warren R. L. Cairns, Alice Callegaro, David Cappelletti, Federico Dallo, Marianna D'Amico, Matteo Feltracco, Jean-Charles Gallet, Andrea Gambaro, Catherine Larose, Niccolo Maffezzoli, Mauro Mazzola, Ivan Sartorato, Federico Scoto, Clara Turetta, Massimiliano Varde, Zhiyong Xie, Andrea Spolaor
Summary: The Arctic region is facing contamination from long-range pollution and local human activities. Polycyclic Aromatic Hydrocarbons (PAHs) are used as environmental indicators for emission, transport, and deposition processes. Research conducted in the Arctic surface snow in Ny-Ålesund, Svalbard from October 2018 to May 2019 shows that long-range inputs of PAHs mainly occur in winter, while the most abundant analyte retene exhibits opposite seasonal trends.
ENVIRONMENTAL POLLUTION
(2024)
Review
Environmental Sciences
Maoshui Zhuo, Zhijie Chen, Xiaoqing Liu, Wei Wei, Yansong Shen, Bing-Jie Ni
Summary: This paper discusses the application of three catalytic processes (photocatalysis, electrocatalysis, and biocatalysis) in the management of microplastic pollution, and introduces the efficiency and catalytic mechanisms of different catalysts. It also proposes the development prospects for sustainable management of microplastic pollution.
ENVIRONMENTAL POLLUTION
(2024)
Article
Environmental Sciences
Shiyu Chen, Zhenzhen Shi, Qiang Zhang
Summary: In this study, a human physiologically based pharmacokinetic (PBPK) model of diethyl phthalate (DEP) was developed to assess its toxicity. The model considers the distribution and metabolism of DEP and its active metabolite monoethyl phthalate (MEP) in different tissue compartments. Sensitivity analysis and Bayesian Markov chain Monte Carlo (MCMC) simulations were performed to evaluate the uncertainty and variability of the model parameters. The results suggest that dermal absorption is an important route of exposure to DEP in the environment.
ENVIRONMENTAL POLLUTION
(2024)
Article
Environmental Sciences
Bangguo Wang, Lijing Wang, Wenxi Cen, Tao Lyu, Peter Jarvis, Yang Zhang, Yuanxun Zhang, Yinghui Han, Lei Wang, Gang Pan, Kaili Zhang, Wei Fan
Summary: This study investigates the feasibility and mechanisms of a chemical-free nanobubble-based AOP for treating organic micropollutants in water. The results show that the oxygen nanobubble AOP has a significantly higher removal efficiency compared to air and nitrogen nanobubbles. The treatment performance is not affected by pH and the presence of ions. Higher initial concentrations of the micropollutant lead to slower treatment processes, but similar removal performance is achieved in the end. The presence of organic matter reduces the removal rate of the micropollutant. The results have practical feasibility for water and wastewater treatment.
ENVIRONMENTAL POLLUTION
(2024)
Article
Environmental Sciences
Yingmei Huang, Jicai Yi, Yao Huang, Songxiong Zhong, Bin Zhao, Jing Zhou, Yuxuan Wang, Yiwen Zhu, Yanhong Du, Fangbai Li
Summary: This study investigates the impact of biochar on methylmercury (MeHg) accumulation in rice. The results show that biochar reduces MeHg levels in paddy soils by decreasing bioavailable Hg and microbial Hg methylation. Additionally, biochar decreases the uptake and translocation of MeHg in rice plants, resulting in a reduction of MeHg accumulation in rice grains.
ENVIRONMENTAL POLLUTION
(2024)
Article
Environmental Sciences
Nengde Zeng, Fei Huang, Jiani Du, Chenghao Huang, Qian Yang, Xinhua Zhan, Baoshan Xing
Summary: This study investigates the protein targets and protein-ligand interactions related to PAH contamination in crop xylem sap using computational tools. The results show that phenanthrene has a more pronounced effect on the xylem sap proteins of maize and wheat, with maize DEPs associated with lipid biosynthesis and wheat DEPs exhibiting an increase in ABC transporters. This study provides insights into the regulation and movement of PAHs within plant xylem.
ENVIRONMENTAL POLLUTION
(2024)
Article
Environmental Sciences
Xinwei Chen, Hao Ma, Run Wang, Man Wang, Binbin Zhu, Yanqing Cong, Xiayue Zhu, Guoqin Wang, Yi Zhang
Summary: Co3O4/TiO2-NRs electrodes with excellent photoresponse were prepared via plasma-assisted modification of Co3O4 on TiO2. The combination of Co3O4 and TiO2 improved the light utilization efficiency and showed potential for degradation of pollutants.
ENVIRONMENTAL POLLUTION
(2024)
Article
Environmental Sciences
Wenjing Ji, Liying Song, Jing Wang, Hongqing Song
Summary: This study conducted a life-cycle assessment to examine the correlation between natural gas consumption and carbon emissions in different end uses in China. The results showed that both natural gas consumption and life-cycle carbon emissions have been increasing since 2017. Significant variations in NG life-cycle carbon emissions were found across different provinces and sectors, highlighting the need for targeted efforts to reduce carbon emissions.
ENVIRONMENTAL POLLUTION
(2024)
Article
Environmental Sciences
Youyi Chen, Boxuan Zhang, Pojun Zhang, Guogui Shi, Hao Liang, Wu Cai, Jingyu Gao, Sumin Zhuang, Kaiyin Luo, Jiaqi Zhu, Chaoxiang Chen, Kunyu Ma, Jinrong Chen, Chun Hu, Xueci Xing
Summary: The synergistic effects of trace sulfadiazine and cast-iron corrosion scales on the formation of disinfection by-products in drinking water distribution systems were investigated. The presence of magnetite resulted in increased concentrations of DBPs due to the higher microbial activity and enhanced microbial extracellular electron transport pathway. The study highlights the importance of considering trace antibiotics pollution and corrosion scales in water sources for DBP control.
ENVIRONMENTAL POLLUTION
(2024)
Review
Environmental Sciences
Bishwa Raj Pokharel, Vijay Sheri, Manoj Kumar, Zhiyong Zhang, Baohong Zhang
Summary: This review summarizes the interactions, uptake, and transport of aluminum nanoparticles (Al-NPs) in plants, highlighting their negative effects on plant growth and development, as well as their potential to alter plant defense systems and gene expression.
ENVIRONMENTAL POLLUTION
(2024)
Article
Environmental Sciences
Yonglu Wang, Fengsong Zhang, Xiaoyong Liao, Xiao Yang, Guixiang Zhang, Liyun Zhang, Chaojun Wei, Pengge Shi, Jiongxin Wen, Xiaorong Ju, Can Xu, Yang Liu, Ying Lan
Summary: This study aims to explore the effects of thiencarbazone-methyl center dot isoxaflutole on soil microflora and the potential mitigation mechanisms to bacterial communities. It was found that increasing the application of thiencarbazone-methyl center dot isoxaflutole resulted in increased stress on soil bacterial community structure and diversity. Increasing soil pH was recognized as a key factor in improving the diversity and structure of soil microflora. Supplemental use of nitrapyrin or modified attapulgite can increase soil pH and improve bacterial diversity.
ENVIRONMENTAL POLLUTION
(2024)