Recent Advances on Nanozyme-based Electrochemical Biosensors

Nanozymes are nanomaterials with enzyme-like catalytic activities. The unique features of nanozymes (such as high stability, low cost, large surface area for bioconjugation, ease of storage, and multi-functionalities) offer unprecedented opportunities for designing electrochemical biosensors. Recent years have witnessed the rapid development of nanozyme-based electrochemical biosensors. To highlight these achievements, this review first discusses the representative nanozymes including peroxidase mimics, oxidase mimics, hydrolase mimics, and superoxide dismutase mimics used in electrochemical biosensors. Then, it summarizes the bioanalytical applications for the detection of various analytes. Finally, current challenges and future research directions are summarized.

Automated summary

This review highlights the applications of nanozymes in electrochemical biosensors, including different types of nanozymes and the methods for detecting various analytes. In addition, current challenges and future research directions are discussed.