Review
Environmental Sciences
Huanhuan Zhu, Yanling Wu, Xingya Kuang, Hanting Liu, Zheng Guo, Jing Qian, Dafei Wang, Meilin Wang, Haiyan Chu, Weida Gong, Zhengdong Zhang
Summary: The study found a significant correlation between PM2.5 exposure and increased levels of circulating fibrinogen and IL-6. Higher levels of PM2.5 exposure were more significantly associated with circulating IL-6 levels, while the association with circulating fibrinogen was less pronounced.
Article
Environmental Sciences
Zhigang Li, Qiaoqiao Su, Rongrong Xu, Jianhao Peng, Zhanshan Wang, Xiaojing Zhu, Yongjie Wei
Summary: This study investigated the association between PM2.5 exposure and RNA m6A methylation as well as PTGS2 levels in peripheral blood. The results showed that increased PM2.5 exposure was associated with higher levels of global RNA m6A methylation and PTGS2. Additionally, the study found hypermethylation of PTGS2 mRNA after high concentrations of PM2.5 exposure, which coincided with increased PTGS2 expression.
ENVIRONMENTAL POLLUTION
(2023)
Article
Environmental Sciences
Huaying Wu, Chao Dong, Wenwen Xiao, Hongcheng Wei, Yunmin Shao, Ting Chen, Yankai Xia
Summary: This study aimed to investigate the association between PM2.5 exposure, oral microbiota, and infant growth. The results showed that PM2.5 exposure from 10th to 12th month after birth was associated with decreased linear growth of infants. PM2.5 exposure also had an impact on the oral microbiota of one-year-old infants. Specific bacteria and co-abundance groups (CAGs) related to growth were identified, and Megasphaera was found to mediate the effects of PM2.5 exposure on weight and BMI z scores of infants born within the first three months.
SCIENCE OF THE TOTAL ENVIRONMENT
(2022)
Article
Environmental Sciences
Jiahao Song, Man Cheng, Bin Wang, Min Zhou, Zi Ye, Lieyang Fan, Linling Yu, Xing Wang, Jixuan Ma, Weihong Chen
Summary: This study aimed to explore the potential role of miR-4301 in PM2.5 exposure-associated lung function reduction. The results showed that personal PM2.5 exposure was negatively associated with lung function and plasma miR-4301 expression. Additionally, miR-4301 partially mediated the lung function reduction associated with PM2.5 exposure, possibly through regulating the Wnt signaling pathway.
ENVIRONMENTAL POLLUTION
(2023)
Article
Environmental Sciences
Wanzhou Wang, Wenlou Zhang, Luyi Li, Jing Huang, Dayu Hu, Shan Liu, Junhui Xu, Liyan Cui, Junxiu Liu, Shaowei Wu, Xinbiao Guo, Furong Deng
Summary: Noise pollution increases the risks of cardiovascular disorders, and personal exposure to noise affects cardiac autonomic function. Obesity and PM2.5 exacerbate the adverse effects of noise on heart rate variability.
ENVIRONMENTAL RESEARCH
(2022)
Article
Geriatrics & Gerontology
Zirong Ye, Xueru Li, Haoxiang Lang, Ya Fang
Summary: This study found that long-term exposure to PM2.5 is associated with decreased lung function and cognitive impairment. It investigated whether the effect of PM2.5 on cognitive function is mediated by lung function. The results showed that lung function partially mediates the association between long-term PM2.5 exposure and cognition. Therefore, more clean air actions should be taken to improve lung function and cognitive function in older adults.
JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES
(2023)
Article
Engineering, Environmental
Zixuan Liu, Qiushuang Zhu, Erqun Song, Yang Song
Summary: This study investigated the protein corona formed on PM2.5 particles in biological fluids and found differences in corona composition between plasma and after BALF exposure. The results showed an abundance of serum albumin, hemoglobin, and fibrinogen proteins in the corona, and highlighted the contributions of various types of interactions in the adsorption process. Additionally, the study demonstrated that the protein corona could affect cellular internalization of PM2.5 and subsequent oxidative stress responses.
JOURNAL OF HAZARDOUS MATERIALS
(2021)
Article
Biophysics
Alba Camacho-Cardenosa, Marta Camacho-Cardenosa, Pablo Tomas-Carus, Rafael Timon, Guillermo Olcina, Martin Burtscher
Summary: This study aimed to explore the differences in cardiorespiratory responses to normobaric hypoxia between men and women. The results showed that men had a more pronounced ventilatory response to hypoxia compared to women, while women experienced a faster decrease in peripheral oxygen saturation during the first few hours in hypoxia.
INTERNATIONAL JOURNAL OF BIOMETEOROLOGY
(2022)
Article
Psychology, Biological
Mark A. Wetherell, Shing-Hon Lau, Roy A. Maxion
Summary: Typing rhythms can indicate whether individuals are stressed or not, but the features used for classification differ between individuals. Analyzing typing rhythms can help identify disorders that may impact motor control and can be used to monitor the health status of keyboard users in various situations.
Article
Environmental Sciences
Octavio Gamaliel Aztatzi-Aguilar, Gabriela Andrea Pardo-Osorio, Marisela Uribe-Ramirez, Juana Narvaez-Morales, Andrea De Vizcaya-Ruiz, Olivier Christophe Barbier
Summary: Exposure to PM2.5 is associated with acute kidney damage, oxidative stress, inflammation, and potential loss of renal function, as evidenced by increased early kidney damage biomarkers and inflammatory markers.
ENVIRONMENTAL TOXICOLOGY AND PHARMACOLOGY
(2021)
Article
Environmental Sciences
Xiaolong Xing, Fangchao Liu, Xueli Yang, Qiong Liu, Xinyan Wang, Zhennan Lin, Keyong Huang, Jie Cao, Jianxin Li, Meng Fan, Xiaotian Chen, Cuizhen Zhang, Shufeng Chen, Xiangfeng Lu, Dongfeng Gu, Jianfeng Huang
Summary: Exposure to PM2.5 was found to decrease HRV, but this effect can be mitigated in patients with controlled blood pressure or receiving ARB treatment. These findings suggest that better BP control and ARB treatment could help alleviate the adverse impacts of PM2.5 exposure on HRV.
ENVIRONMENTAL POLLUTION
(2021)
Article
Environmental Sciences
Yang Li, Josevata Werelagi Batibawa, Zhou Du, Shuang Liang, Junchao Duan, Zhiwei Sun
Summary: Our study found that acute exposure to diverse dosages of PM2.5 can trigger inflammatory response and cell apoptosis, attributed to severe oxidative stress. Activation of the Nrf2-ARE pathway serves as an important compensatory process for antioxidant damage during the early stage of exposure to PM2.5. Enhancing HO-1 expression may mitigate cell apoptosis caused by PM2.5 exposure.
ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY
(2021)
Article
Engineering, Environmental
Pallavi Joshi, Sagnik Dey, Santu Ghosh, Srishti Jain, Sudhir Kumar Sharma
Summary: This study reveals the association between acute exposure to PM2.5 chemical species and mortality in Delhi, India. The study found that different chemical components have varying effects on mortality risk, with differences in gender, age group, and season. Winter exposure to PM2.5 chemical species poses the greatest mortality risk.
ENVIRONMENTAL SCIENCE & TECHNOLOGY
(2022)
Article
Environmental Sciences
Jongmin Oh, Sangbum Choi, Changwoo Han, Dong-Wook Lee, Eunhee Ha, Soontae Kim, Hyun-Joo Bae, Wook Bum Pyun, Yun-Chul Hong, Youn-Hee Lim
Summary: A study in South Korea found that long-term exposure to PM2.5 increases the risk of cardiovascular morbidity and mortality among patients with ischemic heart disease, particularly those aged 65-74 years.
ENVIRONMENTAL RESEARCH
(2023)
Article
Physiology
Catherine A. Lizamore, Lee Stoner, Yaso Kathiravel, John Elliott, Michael J. Hamlin
Summary: The aim of this study was to investigate whether exercise supplemented with passive intermittent hypoxic exposure (IHE) improved cardiovascular disease risk and related factors. The results showed that adding IHE to exercise in inactive adults may have beneficial effects on cardiovascular health markers, but it may also increase myocardial load.
FRONTIERS IN PHYSIOLOGY
(2022)
Review
Environmental Sciences
Zhiping Niu, Zhizhou Duan, Hongmei Yu, Lina Xue, Feifei Liu, Dong Yu, Keying Zhang, Donghui Han, Weihong Wen, Hao Xiang, Weijun Qin
Summary: Recent studies suggest that long-term exposure to particulate matter is associated with increased blood pressure and hypertension risk.
INTERNATIONAL JOURNAL OF ENVIRONMENTAL HEALTH RESEARCH
(2023)
Article
Environmental Sciences
Su-chun Wang, Guang-zhou Liu, Fei-fei Liu
Summary: This study investigated the physiological and metabolic effects of polystyrene (PS) and aged polystyrene (A-PS) microplastics on Dunaliella salina. It was found that they inhibited the growth of microalgae but promoted pigment synthesis. Oxidative stress analysis showed that PS and A-PS caused oxidative damage to algal cells. Metabolomics analysis showed that PS and A-PS significantly increased different metabolites.
ENVIRONMENTAL POLLUTION
(2023)
Article
Construction & Building Technology
Chenglong Shi, Jigang Zhang, Xiangying Wang, Feifei Liu, Wenli Chen, Zhehao Ma, Haizhi Liang, Yang Zhao
Summary: Pendulum impact testing and numerical analysis were conducted for the first time on civil air defense walls sprayed with 2-mm polyisocyanate-oxazodone (POZD) coatings at different positions, in order to prevent serious casualties and secondary injuries caused by high-speed splashing concrete fragments. The results showed that spraying a 2-mm POZD coating can significantly reduce damage, restrain splashing of fragments, ensure wall integrity, and improve impact resistance and airtightness. Additionally, using large-rupture-strain fiber-reinforced polymer (FRP) on the back improved bending stiffness and deformation capacity, reducing residual displacement. The failure modes and characteristics obtained from this study provide evaluation criteria for existing civil air defense walls.
JOURNAL OF STRUCTURAL ENGINEERING
(2023)
Review
Oncology
Ronald Chow, Julie Midroni, Jagdeep Kaur, Gabriel Boldt, Geoffrey Liu, Lawson Eng, Fei-Fei Liu, Benjamin Haibe-Kains, Michael Lock, Srinivas Raman
Summary: The aim of this study is to provide a comprehensive understanding of the current landscape of artificial intelligence (AI) for cancer clinical trial enrollment and its predictive accuracy. The study found that AI demonstrated comparable or superior performance to manual screening for patient enrollment in cancer clinical trials, with accuracy, sensitivity, and specificity exceeding 80% in most datasets. AI is highly efficient and requires less time and human resources for screening patients.
JNCI-JOURNAL OF THE NATIONAL CANCER INSTITUTE
(2023)
Article
Engineering, Marine
Qingfeng Yan, Jigang Zhang, Feifei Liu, Zhehao Ma, Guoliang Zhao, Chi Gu, Hanyu Song, Yang Zhao
Summary: This study investigates the performance of T-joints in the jacket foundation of offshore wind turbines under impact loading by means of experimental and simulation analysis. The deformation pattern and dynamic response of one hollow T-joint and eight concrete-filled double steel tubular T-joints (CFDST T-joints) are explored through a pendulum testing machine. The experimental results indicate that the local indentation dominates in the deformation process of hollow T-joint while the failure mode of CFDST T-joint will be commonly the global bending. The impact force-displacement curves corresponding to different parameters have similar tendencies and each curve can be divided into four stages. Increasing the impact velocity and axial compression ratio can reduce impact resistance. Meanwhile, increasing outer tube thickness and changing hollow rate exert a remarkable effect on the dynamic performance. Finite element models are then proposed to validate the experimental results and investigate the energy dissipation mechanism of T-joints under impact loading. The plastic deformation of the outer tube is the main energy dissipation mechanism for CFDST T-joints. In general, the investigation in this study offers a reliable basis for the study of impact failure mechanism for CFDST T-joint.
Article
Engineering, Mechanical
Fei-Fei Liu, Xing Lu, Jian-Ping Wang, Yi-Cheng Wu
Summary: This paper focuses on the dynamical behavior and modulation instability of optical solitons in nonlinear directional couplers. The expressions of single soliton solutions are derived, and the hyperbolic secant-type pulse is used to excite the input channel. The dynamical behavior of single optical soliton in traditional directional and negative index material couplers with varying self-phase modulation is discussed. Based on linear stability analysis, the distribution of modulation instability gain is studied, and the effect of dispersion, nonlinearity, and input power on modulation instability gain is investigated. It is worth noting that the physical information neural network algorithm performs well in simulating the transmission of an optical pulse in the coupler and leading to novel optical waves. These results contribute to understanding the generation of soliton-like excitation and lay a foundation for exploring novel optical solitons in nonlinear directional couplers.
NONLINEAR DYNAMICS
(2023)
Article
Geochemistry & Geophysics
Yuan Sun, Feifei Liu, Jia Liu, Liangxi Chen, Yan Li, Hongrui Ding, Anhuai Lu
Summary: In this study, a simulated photoelectron system was used to investigate the effects of semiconducting mineral photoelectrons on the microbial community and sulfate reduction. The results showed that photoelectrons had significant impacts on microbial community diversity and sulfate reduction rate, and promoted the enrichment of sulfate-reducing bacteria. This process has important implications for carbon and sulfur element cycling as well as the formation of dolomite.
Article
Engineering, Marine
Qingfeng Yan, Jigang Zhang, Zhehao Ma, Feifei Liu, Guoliang Zhao, Chi Gu, Hanyu Song, Weicheng Zhang
Summary: This study investigates the effect of impact force and axial force on the dynamic response of CFDST-K joints in offshore wind turbine (OWT) applications. Experimental and numerical methods are used to analyze the deformation property and dynamic response of the joints. The results show that increasing impact energy leads to higher impact force, displacement, and plastic strain. Improving the axial compression ratio and flexural stiffness enhances the deformation and impact performance of the joints.
Article
Engineering, Marine
Feifei Liu, Jigang Zhang, Jia Sun, Di Zhao, Da Gao, Zhehao Ma, Hanyu Song, Ruixue Wu, Weicheng Zhang
Summary: Ice loading is the main design load for offshore platforms in Bohai Bay. The ice-induced vibration of the platform was studied, and two different designs with concrete filled double-skin legs were tested. The results showed that both platform designs reduced the ice-induced vibration, with the self-centering design having a better control effect. The use of concrete filled double-skin legs improved the structural stiffness and the addition of prestressed tendons further improved the platform's performance.
Article
Optics
Yizhen Chen, Xiaoying Zheng, Feifei Liu, Weikang Pan, Zhuo Wang, Muhan Liu, Zhiyan Zhu, Yingying Wang, Liangwei Li, Qiong He, Lei Zhou, Shulin Sun
Summary: By constructing high-efficiency bifunctional metasurfaces, we have successfully generated two plasmonic vortices with distinct topological charges, which can find wide applications in on-chip photonics.
Article
Chemistry, Analytical
Feifei Liu, Haoyu Jia, Yuxue Chen, Xiaoai Luo, Meidong Huang, Meng Wang, Xinping Zhang
Summary: Localized surface plasmon resonance (LSPR)-based sensors have great potential in medical diagnosis, food safety regulation, and environmental monitoring. This paper presents an improved plasmonic sensor based on Fano resonances between LSPR and the Rayleigh anomaly (RA), which allows for the formation of narrowband reflection peaks within the LSPR-based broadband extinction window. By carefully adjusting the angles of incident light, the sensor can be optimized for detecting local refractive index changes caused by the bonding of target molecules on the surface of the nano-device. The hybrid sensor demonstrates significantly higher figure of merit (FOM) compared to traditional RA- and LSPR-based sensors.
Article
Engineering, Civil
Di Zhao, Jigang Zhang, Feifei Liu, Zhehao Ma, Guoliang Zhao, Chi Gu, Weicheng Zhang, Hanyu Song
Summary: The dynamic response to lateral impact of steel tube confined concrete with a circular hollow section was investigated through laboratory pendulum impact tests. The results showed that increasing the outer wall thickness and adopting an appropriate hollow ratio can effectively improve the impact resistance of such columns.
THIN-WALLED STRUCTURES
(2023)
Article
Public, Environmental & Occupational Health
Xiu Jin, Feifei Liu, Ya Zhang, Yingying Ma, Linqing Yang, Yunfei Wang, Ying Liu
Summary: This study aimed to investigate the infection status of HR-HPV E6/E7 mRNA in ASCUS patients and analyze the pathogenic rate of different HPV subtypes, providing a more accurate basis for managing ASCUS patients. It was found that colposcopy referral or further biopsy is recommended for ASCUS patients with HPV16/18/45E6/E7 mRNA positivity and postmenopausal patients with HR-HPVE6/E7 mRNA positivity.
Article
Radiology, Nuclear Medicine & Medical Imaging
Feifei Liu, Mingtong Liu, Meiting Li, Yuwei Xin, Dongping Gao, Jun Wu, Jiaan Zhu
Summary: This study successfully extracted relevant knowledge from Chinese electronic medical records using a small number of manually annotated samples and established a knowledge graph for rheumatoid arthritis using a combination of pretrained language models and deep neural networks.
QUANTITATIVE IMAGING IN MEDICINE AND SURGERY
(2023)
Meeting Abstract
Oncology
Matthew Lunning, Kristen A. Deger, Fei Fei Liu, Ahmed Elsada, Sven L. Klijn, Michal Litkiewicz, Conrado Franco-Villalobos, Sonja V. Sorensen
CLINICAL LYMPHOMA MYELOMA & LEUKEMIA
(2023)