Direct and Sequential Bioactivation of Pemigatinib to Reactive Iminium Ion Intermediates Culminate in Mechanism-Based Inactivation of Cytochrome P450 3A

标题
Direct and Sequential Bioactivation of Pemigatinib to Reactive Iminium Ion Intermediates Culminate in Mechanism-Based Inactivation of Cytochrome P450 3A
作者
关键词
-
出版物
DRUG METABOLISM AND DISPOSITION
Volume -, Issue -, Pages DMD-AR-2021-000804
出版商
American Society for Pharmacology & Experimental Therapeutics (ASPET)
发表日期
2022-02-13
DOI
10.1124/dmd.121.000804

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