Ulotaront, a novel TAAR1 agonist with 5-HT1A agonist activity, lacks abuse liability and attenuates cocaine cue-induced relapse in rats

Towards Novel Treatments for Schizophrenia: Molecular and Behavioural Signatures of the Psychotropic Agent SEP-363856

(2021) Veronica Begni et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

TAAR1 and Psychostimulant Addiction

(2020) Jianfeng Liu et al.   CELLULAR AND MOLECULAR NEUROBIOLOGY

Reproducing the dopamine pathophysiology of schizophrenia and approaches to ameliorate it: a translational imaging study with ketamine

(2020) Michelle Kokkinou et al.   MOLECULAR PSYCHIATRY

A Non–D2-Receptor-Binding Drug for the Treatment of Schizophrenia

(2020) Kenneth S. Koblan et al.   NEW ENGLAND JOURNAL OF MEDICINE

SEP-363856, A NOVEL PSYCHOTROPIC AGENT WITH A UNIQUE, NON-D2 RECEPTOR MECHANISM OF ACTION

(2019) Nina Dedic et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

Role of trace amine-associated receptor 1 in nicotine’s behavioral and neurochemical effects

(2018) Jian-Feng Liu et al.   NEUROPSYCHOPHARMACOLOGY

Trace Amines and Their Receptors

(2018) Raul R. Gainetdinov et al.   PHARMACOLOGICAL REVIEWS

Pharmacology of human trace amine-associated receptors: Therapeutic opportunities and challenges

(2017) Mark D. Berry et al.   PHARMACOLOGY & THERAPEUTICS

Interaction Between the Trace Amine-Associated Receptor 1 and the Dopamine D2 Receptor Controls Cocaine’s Neurochemical Actions

(2017) Aman Asif-Malik et al.   Scientific Reports

A partial trace amine-associated receptor 1 agonist exhibits properties consistent with a methamphetamine substitution treatment

(2016) Yue Pei et al.   ADDICTION BIOLOGY

Current FDA regulatory guidance on the conduct of drug discrimination studies for NDA review: Does the scientific literature support recent recommendations?

(2016) David V. Gauvin et al.   DRUG AND ALCOHOL DEPENDENCE

The effects in rats of lisdexamfetamine in combination with olanzapine on mesocorticolimbic dopamine efflux, striatal dopamine D 2 receptor occupancy and stimulus generalization to a d -amphetamine cue

(2016) Peter H. Hutson et al.   NEUROPHARMACOLOGY

The Trace Amine-Associated Receptor 1 Agonist RO5256390 Blocks Compulsive, Binge-like Eating in Rats

(2016) Antonio Ferragud et al.   NEUROPSYCHOPHARMACOLOGY

Trace Amines and the Trace Amine-Associated Receptor 1: Pharmacology, Neurochemistry, and Clinical Implications

(2016) Yue Pei et al.   Frontiers in Neuroscience

Trace amine-associated receptor 1: A promising target for the treatment of psychostimulant addiction

(2015) Li Jing et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Selective activation of the trace amine-associated receptor 1 decreases cocaine's reinforcing efficacy and prevents cocaine-induced changes in brain reward thresholds

(2015) Yue Pei et al.   PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY

The trace amine-associated receptor 1 modulates methamphetamine's neurochemical and behavioral effects

(2015) Rachel Cotter et al.   Frontiers in Neuroscience

Effects of the Trace Amine Associated Receptor 1 Agonist RO5263397 on Abuse-Related Behavioral Indices of Methamphetamine in Rats

(2015) L. Jing et al.   INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY

Activation of the Trace Amine-Associated Receptor 1 Prevents Relapse to Cocaine Seeking

(2014) Yui Pei et al.   NEUROPSYCHOPHARMACOLOGY

Effects of the Trace Amine-Associated Receptor 1 Agonist RO5263397 on Abuse-Related Effects of Cocaine in Rats

(2014) David A Thorn et al.   NEUROPSYCHOPHARMACOLOGY

A preclinical evaluation of the discriminative and reinforcing properties of lisdexamfetamine in comparison to d-amfetamine, methylphenidate and modafinil

(2013) David J. Heal et al.   NEUROPHARMACOLOGY

Influence of aripiprazole pretreatment on the reinforcing effects of methamphetamine in humans

(2013) William W. Stoops et al.   PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY

Effect of D1-like and D2-like receptor antagonists on methamphetamine and 3,4-methylenedioxymethamphetamine self-administration in rats

(2009) Katharine A. Brennan et al.   BEHAVIOURAL PHARMACOLOGY

Characterization of methylphenidate self-administration and reinstatement in the rat

(2008) Leigh C. P. Botly et al.   PSYCHOPHARMACOLOGY

Aripiprazole blocks acute self-administration of cocaine and is not self-administered in mice

(2008) Gunnar Sørensen et al.   PSYCHOPHARMACOLOGY