Metformin for pregnancy and beyond: the pros and cons

Diabetes care and pregnancy outcomes for women with pregestational diabetes in Ireland

(2021) C. Newman et al.   DIABETES RESEARCH AND CLINICAL PRACTICE

Characteristics and outcomes of pregnant women with type 1 or type 2 diabetes: a 5-year national population-based cohort study

(2021) Helen R Murphy et al.   Lancet Diabetes & Endocrinology

Cognitive function in metformin exposed children, born to mothers with PCOS – follow-up of an RCT

(2020) Hanne Klæboe Greger et al.   BMC Pediatrics

A core outcome set for studies of gestational diabetes mellitus prevention and treatment

(2020) Aoife M. Egan et al.   DIABETOLOGIA

Metformin in Pregnancy Study (MiPS): protocol for a systematic review with individual patient data meta-analysis

(2020) Aya Mousa et al.   BMJ Open

Progression to type 2 diabetes in women with a known history of gestational diabetes: systematic review and meta-analysis

(2020) Elpida Vounzoulaki et al.   BMJ-British Medical Journal

Metformin in women with type 2 diabetes in pregnancy (MiTy): a multicentre, international, randomised, placebo-controlled trial

(2020) Denice S Feig et al.   Lancet Diabetes & Endocrinology

Use of metformin to treat pregnant women with polycystic ovary syndrome (PregMet2): a randomised, double-blind, placebo-controlled trial

(2019) Tone S Løvvik et al.   Lancet Diabetes & Endocrinology

Follow-up at 1 year and beyond of women with gestational diabetes treated with insulin and/or oral glucose-lowering agents: a core outcome set using a Delphi survey

(2019) Delia Bogdanet et al.   DIABETOLOGIA

SUGAR-DIP trial: oral medication strategy versus insulin for diabetes in pregnancy, study protocol for a multicentre, open-label, non-inferiority, randomised controlled trial

(2019) Leon de Wit et al.   BMJ Open

Neonatal, infant, and childhood growth following metformin versus insulin treatment for gestational diabetes: A systematic review and meta-analysis

(2019) Jane L. Tarry-Adkins et al.   PLOS MEDICINE

Comparative Efficacy and Safety of Metformin, Glyburide, and Insulin in Treating Gestational Diabetes Mellitus: A Meta-Analysis

(2019) Lanlan Guo et al.   Journal of Diabetes Research

14. Management of Diabetes in Pregnancy: Standards of Medical Care in Diabetes—2020

(2019)   DIABETES CARE

Pregnancy outcomes in women on metformin for diabetes or other indications among those seeking teratology information services

(2018) Alice Panchaud et al.   BRITISH JOURNAL OF CLINICAL PHARMACOLOGY

Metformin Use in PCOS Pregnancies Increases the Risk of Offspring Overweight at 4 Years of Age: Follow-Up of Two RCTs

(2018) Liv Guro Engen Hanem et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Organic Cation Transporter 3 Facilitates Fetal Exposure to Metformin During Pregnancy

(2018) Nora Lee et al.   MOLECULAR PHARMACOLOGY

Metformin exposure in first trimester of pregnancy and risk of all or specific congenital anomalies: exploratory case-control study

(2018) Joanne E Given et al.   BMJ-British Medical Journal

Metformin exposure in first trimester of pregnancy and risk of all or specific congenital anomalies: exploratory case-control study

(2018) Joanne E Given et al.   BMJ-British Medical Journal

Estimated global overweight and obesity burden in pregnant women based on panel data model

(2018) Cheng Chen et al.   PLoS One

Effect of metformin in addition to dietary and lifestyle advice for pregnant women who are overweight or obese: the GRoW randomised, double-blind, placebo-controlled trial

(2018) Jodie M Dodd et al.   Lancet Diabetes & Endocrinology

Influence of maternal obesity on the long-term health of offspring

(2017) Keith M Godfrey et al.   Lancet Diabetes & Endocrinology

Decreased activation of placental mTOR family members is associated with the induction of intrauterine growth restriction by secondhand smoke in the mouse

(2016) Camilo Mejia et al.   CELL AND TISSUE RESEARCH

Born Large for Gestational Age: Bigger Is Not Always Better

(2016) Valentina Chiavaroli et al.   JOURNAL OF PEDIATRICS

Trends in adult body-mass index in 200 countries from 1975 to 2014: a pooled analysis of 1698 population-based measurement studies with 19·2 million participants

(2016)   LANCET

Effects of metformin on pregnancy outcomes in women with polycystic ovary syndrome

(2016) Xian-Ling Zeng et al.   MEDICINE

Long-term metabolic risk among children born premature or small for gestational age

(2016) Veronica Mericq et al.   Nature Reviews Endocrinology

Metformin versus Placebo in Obese Pregnant Women without Diabetes Mellitus

(2016) Argyro Syngelaki et al.   NEW ENGLAND JOURNAL OF MEDICINE

The Effect of Lifestyle Intervention and Metformin on Preventing or Delaying Diabetes Among Women With and Without Gestational Diabetes: The Diabetes Prevention Program Outcomes Study 10-Year Follow-Up

(2015) V. R. Aroda et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Metformin Treatment in Type 2 Diabetes in Pregnancy: An Active Controlled, Parallel-Group, Randomized, Open Label Study in Patients with Type 2 Diabetes in Pregnancy

(2015) Jahan Ara Ainuddin et al.   Journal of Diabetes Research

Effect of metformin on maternal and fetal outcomes in obese pregnant women (EMPOWaR): a randomised, double-blind, placebo-controlled trial

(2015) Carolyn Chiswick et al.   Lancet Diabetes & Endocrinology

A follow-up of a randomised study of metformin and insulin in gestational diabetes mellitus: growth and development of the children at the age of 18 months

(2014) H Ijäs et al.   BJOG-AN INTERNATIONAL JOURNAL OF OBSTETRICS AND GYNAECOLOGY

First-trimester exposure to metformin and risk of birth defects: a systematic review and meta-analysis

(2014) Matteo Cassina et al.   HUMAN REPRODUCTION UPDATE

Metformin in reproductive health, pregnancy and gynaecological cancer: established and emerging indications

(2014) Vanitha N. Sivalingam et al.   HUMAN REPRODUCTION UPDATE

Metformin—mode of action and clinical implications for diabetes and cancer

(2014) Ida Pernicova et al.   Nature Reviews Endocrinology

Lack of metformin effect on mouse embryo AMPK activity: implications for metformin treatment during pregnancy

(2013) Hyung-yul Lee et al.   DIABETES-METABOLISM RESEARCH AND REVIEWS

Metformin Compared with Insulin in the Treatment of Pregnant Women with Overt Diabetes: A Randomized Controlled Trial

(2012) M. Hickman et al.   AMERICAN JOURNAL OF PERINATOLOGY

Metformin vs. insulin in gestational diabetes. A randomized study characterizing metformin patients needing additional insulin

(2012) K. Tertti et al.   DIABETES OBESITY & METABOLISM

Metformin compared with insulin in the management of gestational diabetes mellitus: A randomized clinical trial

(2012) Shirin Niromanesh et al.   DIABETES RESEARCH AND CLINICAL PRACTICE

Growth, body composition and metabolic profile of 8-year-old children exposed to metforminin utero

(2012) Torstein B. Rø et al.   SCANDINAVIAN JOURNAL OF CLINICAL & LABORATORY INVESTIGATION

Metformin in Gestational Diabetes: The Offspring Follow-Up (MiG TOFU): Body composition at 2 years of age

(2011) J. A. Rowan et al.   DIABETES CARE

Metformin should be considered in the treatment of gestational diabetes: a prospective randomised study

(2010) H Ijäs et al.   BJOG-AN INTERNATIONAL JOURNAL OF OBSTETRICS AND GYNAECOLOGY

MetforminVersusPlacebo from First Trimester to Delivery in Polycystic Ovary Syndrome: A Randomized, Controlled Multicenter Study

(2010) Eszter Vanky et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Pregnancy Insulin, Glucose, and BMI Contribute to Birth Outcomes in Nondiabetic Mothers

(2008) K. K. Ong et al.   DIABETES CARE

Prevention of Diabetes in Women with a History of Gestational Diabetes: Effects of Metformin and Lifestyle Interventions

(2008) Robert E. Ratner et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Metformin versus Insulin for the Treatment of Gestational Diabetes

(2008) Janet A. Rowan et al.   NEW ENGLAND JOURNAL OF MEDICINE