Review
Materials Science, Multidisciplinary
Joseph D. Tanfani, Jasmin D. Monpara, Sriramakamal Jonnalagadda
Summary: 3D printing is widely used by independent researchers in various fields, with 3D bioprinting being a specific form that utilizes bioinks to create complex, bioactive structures such as artificial skin for wound regeneration. Despite the wide range of available materials and cell types, an ideal bioink for printing artificial skin has yet to be found. This review will discuss the different types of 3D printing, commonly used bioinks, challenges in 3D bioprinting of skin, and future directions for the field.
ADVANCED MATERIALS TECHNOLOGIES
(2023)
Article
Materials Science, Biomaterials
Yu Wu, Tangzhao Liang, Ying Hu, Shihai Jiang, Yuansen Luo, Chang Liu, Guo Wang, Jing Zhang, Tao Xu, Lei Zhu
Summary: The study utilized 3D bioprinting to create 3D-ADSCs/NO hydrogel scaffolds, which enhanced migration and angiogenesis of HUVECs, accelerated burn wound healing in mice by promoting faster epithelialization and collagen deposition, and increased neovascularization through the VEGF signaling pathway, suggesting the scaffold as a promising strategy for treating severe burns.
REGENERATIVE BIOMATERIALS
(2021)
Review
Biochemistry & Molecular Biology
Mohamadreza Aghamirsalim, Mohammadmahdi Mobaraki, Madjid Soltani, Mohammad Kiani Shahvandi, Mahmoud Jabbarvand, Elham Afzali, Kaamran Raahemifar
Summary: Corneal disease is a major cause of blindness worldwide, and corneal transplantation is the only treatment option. However, the scarcity of donated corneas has prompted scientists to explore tissue engineering and regenerative medicine. Bioprinting, utilizing hydrogels as bioink, shows promise in fabricating scaffolds with acceptable biocompatibility for corneal tissue engineering. This review discusses the use of hydrogels as bioink and various bioprinting methods for corneal tissue engineering.
Article
Biophysics
Haibo Huang, Lihang Chen, Yiyang Hou, Wanying He, Xinchuang Wang, Dan Zhang, Jiangning Hu
Summary: This study developed a novel dressing hydrogel using chlorogenic acid (CA) through self-assembly. The CA hydrogel exhibited excellent self-healing, injectability, and biocompatibility properties, making it a promising candidate for wound treatment. In vitro and in vivo experiments demonstrated its anti-inflammatory activity and ability to promote angiogenesis, indicating its potential in wound healing.
COLLOIDS AND SURFACES B-BIOINTERFACES
(2023)
Article
Biotechnology & Applied Microbiology
Nieves Cubo-Mateo, Michael Gelinsky
Summary: Skin wound healing is impaired in space, necessitating the development of new treatment options for severe skin injuries in manned space missions. Three-dimensional bioprinting technology could potentially provide a solution by allowing the manufacturing of complex tissue constructs.
FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY
(2021)
Review
Chemistry, Medicinal
Tracey Anastacia Jeckson, Yun Ping Neo, Sreenivas Patro Sisinthy, Bapi Gorain
Summary: The increasing incidences of chronic wounds have led to the demand for development of effective therapeutic wound treatment. Electrospun nanofiber has been recognized as a better system for wound dressing, with the proposed multilayer structure aiming to address the issues of burst release effect in single-layer designs. This review highlights the potential of layer-by-layer multilayer electrospun nanofiber as a superior strategy for designing optimal wound dressings.
JOURNAL OF PHARMACEUTICAL SCIENCES
(2021)
Article
Nanoscience & Nanotechnology
Santosh Shivaji Biranje, Jianzhong Sun, Lu Cheng, Yu Cheng, Yifei Shi, Sujie Yu, Haixin Jiao, Meng Zhang, Xuechu Lu, Wenjia Han, Qianqian Wang, Zhen Zhang, Jun Liu
Summary: In this study, a 3D composite scaffold was designed using bioprinting technology and synergistic hemostasis mechanisms of cellulose nanofibrils (TCNFs), chitosan, and casein to control blood loss in traumatic hemorrhage. The 3D composite scaffold showed better swelling behavior, faster blood clotting rate, and higher efficiencies for red blood cell entrapping compared to other materials. It also promoted the growth and proliferation of fibroblast cells and demonstrated potential for biodegradation. This study suggests the potential application of 3D composite scaffolds in reducing blood loss during traumatic hemorrhage.
ACS APPLIED MATERIALS & INTERFACES
(2022)
Article
Materials Science, Multidisciplinary
Yufan Zhu, Wei Zhou, Jieyu Xiang, Minhao Wu, Zhe Chen, Zhiqiang Yang, Renxiong Wei, Lin Cai
Summary: In this study, a Janus bilayer electrospun dressing was developed using modified electro-spinning technologies. The dressing consists of a hydrophilic outer layer loaded with deferoxamine (DFO) and a hydrophobic inner layer with mesh-like structure. The Janus dressing showed good biocompatibility and facilitated biofluid drainage, while promoting angiogenesis.
MATERIALS & DESIGN
(2023)
Article
Engineering, Biomedical
Aleksandr A. Levin, Pavel A. Karalkin, Elizaveta V. Koudan, Fedor S. Senatov, Vladislav A. Parfenov, Vladislav A. Lvov, Stanislav V. Petrov, Frederico D. A. S. Pereira, Alexey V. Kovalev, Egor O. Osidak, Sergey P. Domogatsky, Natalya E. Manturova, Vladimir A. Kasyanov, Natalia S. Sergeeva, Vadim L. Zorln, Yusef D. Khesuani, Vladimir A. Mironov
Summary: This study demonstrates the benefits of an originally developed commercial in situ bioprinter for the treatment of skin wounds in rat and porcine models. The in situ bioprinting technique, performed directly on the human body in the operating room, improves the quality of wound healing without interfering with the normal healing process. This suggests that in situ bioprinting could be a novel therapeutic modality in wound healing.
INTERNATIONAL JOURNAL OF BIOPRINTING
(2023)
Article
Engineering, Biomedical
Jueying Chen, Jiahui He, Yutong Yang, Lipeng Qiao, Juan Hu, Jie Zhang, Baolin Guo
Summary: The development of compressible, stretchable and self-healing hydrogel dressings with good adhesive, antibacterial and angiogenesis properties is needed to promote the regeneration of diabetic wounds in clinical applications.
ACTA BIOMATERIALIA
(2022)
Article
Nanoscience & Nanotechnology
Jian Li, Jiang-Nan Chen, Zi-Xin Peng, Ning-Bo Chen, Cheng-Bo Liu, Peng Zhang, Xu Zhang, Guo-Qiang Chen
Summary: In order to treat large-scale wounds or chronic ulcers, a poly(3-hydroxybutyrate-co-4-hydroxybuty-rate) (P34HB) fibrous wound dressing that integrates an antibacterial ciprofloxacin (CIP) and pro-angiogenic dimethyloxalylglycine (DMOG) was successfully prepared. The resulting dressing showed excellent biocompatibility, increased cell proliferation, migration, and capillary-like tube formation. The dressings also exhibited broad-spectrum antimicrobial action and promoted wound closure, reepithelialization, collagen formation, angiogenesis, and hair follicle regeneration. This work provides a simple and efficient approach for the design of versatile wound dressings with antibacterial and angiogenic properties.
ACS APPLIED MATERIALS & INTERFACES
(2023)
Article
Biochemistry & Molecular Biology
Weifang Liao, Xunxin Duan, Fusheng Xie, Dongxi Zheng, Pu Yang, Xiangguo Wang, Zhijian Hu
Summary: In this study, double-crosslinked angiogenic 3D-bioprinted patches were developed for diabetic wound healing. 3D printing technology allows precise customization of patch structure and composition to fulfill clinical requirements. Alginate and chondroitin sulfate methacryloyl were used as biomaterials for constructing the patch, which could be crosslinked using calcium ion crosslinking and photocrosslinking for improved mechanical properties. The acrylylated VEGF could be easily and rapidly photo-crosslinked under UV irradiation, simplifying the process of growth factor coupling and prolonging VEGF release time. These characteristics make 3D-bioprinted double-crosslinked angiogenic patches ideal for diabetic wound healing and other tissue engineering applications.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2023)
Review
Biochemistry & Molecular Biology
Behina Sadat Tabatabaei Hosseini, Kieran Meadows, Vincent Gabriel, Jinguang Hu, Keekyoung Kim
Summary: Despite advancements in wound management, treating most skin injuries and wounds remains challenging in the healthcare industry. Researchers are now exploring innovative materials using cellulose and its derivatives. Cellulose, an abundant biopolymer, possesses unique properties that make it a promising material for wound healing. 3D bioprinting technology allows the production of complex cellulose-based wound dressings that mimic the extracellular matrix. These dressings can promote wound healing by releasing bioactive molecules and retaining moisture. The use of 3D bioprinted cellulose-based wound dressings shows potential in managing chronic wounds, burns, and painful wounds by promoting healing and reducing infection risk.
MACROMOLECULAR BIOSCIENCE
(2023)
Article
Biophysics
Yingjie Zhang, Shuying Zhao, Zhimin Tang, Yan Li, Lu Wang
Summary: An intelligent coaxial electrospun nanofibrous membrane (ENM) was constructed for the treatment and diagnosis of wound biofilm infections. The ENM, composed of core and shell layers, incorporated pH-sensitive alizarin and curcumin for therapy and in situ visualized diagnosis, respectively. Additionally, epsilon-poly -L-lysine (epsilon-PL) was deposited on the ENM to disturb EPS integrity. The ENM showed increased drug susceptibility and could detect the acidic microenvironment of biofilm in situ.
COLLOIDS AND SURFACES B-BIOINTERFACES
(2022)
Article
Instruments & Instrumentation
Katie Glover, Essyrose Mathew, Giulia Pitzanti, Erin Magee, Dimitrios A. Lamprou
Summary: The treatment strategy for diabetic foot ulcer (DFU) is complex, requires multiple therapeutic approaches, and often results in amputation. Bioprinting technologies show innovative potential in fabricating antibiotic scaffolds for DFU treatment.
DRUG DELIVERY AND TRANSLATIONAL RESEARCH
(2023)
Article
Engineering, Environmental
Xinping Zhang, Yuxin Guo, Xiaoyang Liu, Shun-Yu Wu, Ya-Xuan Zhu, Shao-Zhe Wang, Qiu-Yi Duan, Ke-Fei Xu, Zi-Heng Li, Xiao-Yu Zhu, Guang-Yu Pan, Fu-Gen Wu
Summary: This study develops a nanotrigger HCFT for simultaneous photodynamic therapy and light-triggered ferroptosis therapy. The nanotrigger can relieve tumor hypoxia, induce enhanced photodynamic reaction, and facilitate the continuation of Fenton reaction, ultimately leading to lethal ferroptosis in tumor cells.
CHEMICAL ENGINEERING JOURNAL
(2024)
Article
Engineering, Environmental
Olumide Bolarinwa Ayodele, Toyin Daniel Shittu, Olayinka S. Togunwa, Dan Yu, Zhen-Yu Tian
Summary: This study focused on the semihydrogenation of acetylene in an ethylene-rich stream using two alloyed Pt catalysts PtCu and PtCo. The PtCu catalyst showed higher activity and ethylene yield compared to PtCo due to its higher unoccupied Pt d-orbital density. This indicates that alloying Pt with Cu is more promising for industrial relevant SHA catalyst.
CHEMICAL ENGINEERING JOURNAL
(2024)
Article
Engineering, Environmental
Guowei Chen, Wen-Cheng Chen, Yaozu Su, Ruicheng Wang, Jia-Ming Jin, Hui Liang, Bingxue Tan, Dehua Hu, Shaomin Ji, Hao-Li Zhang, Yanping Huo, Yuguang Ma
Summary: This study proposes an intramolecular dual-locking design for organic luminescent materials, achieving high luminescence efficiency and performance for deep-blue organic light-emitting diodes. The material also exhibits unique mechanochromic luminescence behavior and strong fatigue resistance.
CHEMICAL ENGINEERING JOURNAL
(2024)
Article
Engineering, Environmental
Joren van Stee, Gregory Hermans, Jinu Joseph John, Koen Binnemans, Tom Van Gerven
Summary: This work presents a continuous solvent extraction method for the separation of cobalt and nickel in a millifluidic system using Cyphos IL 101 (C101) as the extractant. The optimal conditions for extraction performance and solvent properties were determined by investigating the effects of channel length, flow rate, and temperature. The performance of a developed manifold structure was compared to a single-channel system, and excellent separation results were achieved. The continuous separation process using the manifold structure resulted in high purity cobalt and nickel products.
CHEMICAL ENGINEERING JOURNAL
(2024)
Article
Engineering, Environmental
Yan Xu, Jingai Jiang, Xinyi Lv, Hui Li, Dongliang Yang, Wenjun Wang, Yanling Hu, Longcai Liu, Xiaochen Dong, Yu Cai
Summary: A programmed gas release nanoparticle was developed to address the challenges in treating diabetic infected wounds. It effectively removes drug-resistant pathogens and remodels the wound microenvironment using NO and H2S. The nanoparticle can eliminate bacteria and promote wound healing through antibacterial and anti-inflammatory effects.
CHEMICAL ENGINEERING JOURNAL
(2024)
Article
Engineering, Environmental
Tong Xia, Zhilin Xi, Lianquan Suo, Chen Wang
Summary: This study investigated a highly efficient coal dust suppressant with low initial viscosity and high adhesion-solidification properties. The results demonstrated that the dust suppressant formed a network of multiple hydrogen bonding cross-linking and achieved effective adhesion and solidification of coal dust through various chemical reactions.
CHEMICAL ENGINEERING JOURNAL
(2024)
Article
Engineering, Environmental
Jinzhi Cai, Zhenshan Li
Summary: A density functional theory-based rate equation was developed to predict the gas-solid reaction kinetics of CaO carbonation with CO2 in calcium looping. The negative activation energy of CaO carbonation close to equilibrium was accurately predicted through experimental validation.
CHEMICAL ENGINEERING JOURNAL
(2024)
Article
Engineering, Environmental
Jianxiong Chen, Fuhao Ren, Ningning Yin, Jie Mao
Summary: This study presents an economically efficient and easily implementable surface modification approach to enhance the high-temperature electrical insulation and energy storage performance of polymer dielectrics. The self-assembly of high-insulation-performance boron nitride nanosheets (BNNS) on the film surface through electrostatic interactions effectively impedes charge injection from electrodes while promoting charge dissipation and heat transfer.
CHEMICAL ENGINEERING JOURNAL
(2024)
Article
Engineering, Environmental
Zijian Li, Zhaohui Yang, Shao Wang, Hongxia Luo, Zhimin Xue, Zhenghui Liu, Tiancheng Mu
Summary: This study reports a strategy for upgrading polyester plastics into value-added chemicals using electrocatalytic methods. By inducing the targeted transfer of *OH species, polyethylene terephthalate was successfully upgraded into potassium diformate with high purity. This work not only develops an excellent electrocatalyst, but also provides guidance for the design of medium entropy metal oxides.
CHEMICAL ENGINEERING JOURNAL
(2024)
Article
Engineering, Environmental
Navneet Singh Shekhawat, Surendra Kumar Patra, Ashok Kumar Patra, Bamaprasad Bag
Summary: This study primarily focuses on developing a sulphur dyeing process at room temperature using bacterial Lysate, which is environmentally friendly, energy and cost effective, and sustainable. The process shows promising improvements in dye uptake and fastness properties.
CHEMICAL ENGINEERING JOURNAL
(2024)
Article
Engineering, Environmental
Dengjia Shen, Hongyang Ma, Madani Khan, Benjamin S. Hsiao
Summary: This study developed cationic PVC nanofibrous membranes with high filtration and adsorption capability for the removal of bacteria and hexavalent chromium ions from wastewater. The membranes demonstrated remarkable performance in terms of filtration efficiency and maximum adsorption capacity. Additionally, modified nanofibrous membranes were produced using recycled materials and showed excellent retention rates in dynamic adsorption processes.
CHEMICAL ENGINEERING JOURNAL
(2024)
Article
Engineering, Environmental
Xiaoyan Wang, Zhikun Wang, Ben Jia, Chunling Li, Shuangqing Sun, Songqing Hu
Summary: Inspired by photosystem II, self-supported Fe-doped NiCoP nanowire arrays modified with carboxylate were constructed to boost industrial-level overall water splitting by employing the concerted proton-coupled electron transfer mechanism. The introduction of Fe and carboxyl ligand led to improved catalytic activity for HER and OER, and NCFCP@NF exhibited long-term durability for overall water splitting.
CHEMICAL ENGINEERING JOURNAL
(2024)
Article
Engineering, Environmental
Pengyao Yu, Ge Yang, Yongming Chai, Lubomira Tosheva, Chunzheng Wang, Heqing Jiang, Chenguang Liu, Hailing Guo
Summary: Thin LTA zeolite membranes were prepared through secondary growth of nano LTA seeds in a highly reactive gel, resulting in membranes with superior permeability and selectivity in gas separation applications.
CHEMICAL ENGINEERING JOURNAL
(2024)
Article
Engineering, Environmental
Baiqin Zhou, Huiping Li, Ziyu Wang, Hui Huang, Yujun Wang, Ruichun Yang, Ranran Huo, Xiaoyan Xu, Ting Zhou, Xiaochen Dong
Summary: The use of machine learning to predict the performance of specific adsorbents in phosphate adsorption shows great promise in saving time and revealing underlying mechanisms. However, the small size of the dataset and insufficient detailed information limits the model training process and the accuracy of results. To address this, the study employs a fuzzing strategy that replaces detailed numeric information with descriptive text messages on the physiochemical properties of adsorbents. This strategy allows the recovery of discarded samples with limited information, leading to accurate prediction of adsorption amount, capacity, and kinetics. The study also finds that phosphate uptake by adsorbents is generally through physisorption, with some involvement of chemisorption. The framework established in this study provides a practical approach for quickly predicting phosphate adsorption performance in urgent scenarios, using easily accessible information.
CHEMICAL ENGINEERING JOURNAL
(2024)
Article
Engineering, Environmental
Paula Alejandra Lamprea Pineda, Joren Bruneel, Kristof Demeestere, Lisa Deraedt, Tex Goetschalckx, Herman Van Langenhove, Christophe Walgraeve
Summary: This study evaluates the use of four esterified fatty acids and three vegetable oils as absorption liquids for hydrophobic VOCs. The experimental results show that isopropyl myristate is the most efficient liquid for absorbing the target VOCs.
CHEMICAL ENGINEERING JOURNAL
(2024)