Article
Chemistry, Applied
Xin-yu Wang, Hyun-Joo Kim
Summary: Ionic hydrogel strain sensors are widely used in wearable electronic devices due to their excellent stretchability and responsiveness. However, they are prone to drying at low temperatures, which limits their lifespan and applications. In this study, a dual-network ionic conductive hydrogel was constructed based on alginate/polyacrylamide, which exhibited high strength, moisturizing, antifreeze properties, and cyclic stability. The hydrogel sensor could detect various sizes of tensile deformation and human motion.
PROGRESS IN ORGANIC COATINGS
(2022)
Article
Engineering, Environmental
Cancan Shan, Mingda Che, Aleksander Cholewinski, Joshua Ki Kunihiro, Evelyn K. F. Yim, Rongxin Su, Boxin Zhao
Summary: In this study, conductive hydrogels were tailored by physically crosslinking with cellulose nanofiber (CNF) to create strain sensors that can adhere well to human skin and translate human motions into resistance changes.
CHEMICAL ENGINEERING JOURNAL
(2022)
Article
Engineering, Environmental
Qiuyu Xu, Mohan Hou, Lifang Wang, Xuepeng Zhang, Lifang Liu
Summary: This study utilizes starch/polyvinyl alcohol (PVA) dual-network hydrogel as a substrate to improve the internal compatibility of hydrogels. The hydrogel exhibits high mechanical properties, anti-freezing, anti-bacterial, and electrical conductivity. The assembled hydrogel sensor effectively detects external stimulations and demonstrates high sensitivity and stability.
CHEMICAL ENGINEERING JOURNAL
(2023)
Article
Engineering, Electrical & Electronic
Giorgio Mogli, Annalisa Chiappone, Adriano Sacco, Candido Fabrizio Pirri, Stefano Stassi
Summary: This study presents an extremely flexible strain sensor composed of a cellulose-based hydrogel, which exhibits high sensitivity and a high maximum stretchability. It can be utilized in wearable devices to monitor human motions and physiological signals.
ACS APPLIED ELECTRONIC MATERIALS
(2022)
Article
Chemistry, Multidisciplinary
Yong Long, Bing Jiang, Tianci Huang, Yuxiu Liu, Jianan Niu, Zhong Lin Wang, Weiguo Hu
Summary: Ionic conductive hydrogels have attracted significant attention in flexible/wearable electronics due to their flexibility, tunability, stimulus-response, and self-healing ability. However, traditional hydrogels face challenges such as loss of flexibility and conductivity when exposed to the environment. Organogels have emerged as a promising alternative that can overcome these drawbacks to some extent. This study introduces a self-polymerization reaction to create a super stretchable, anti-drying, and anti-freezing organogel ionic conductor (MOIC). The MOIC is used to construct high-performance triboelectric nanogenerators and multifunctional flexible/wearable sensors, demonstrating its potential for applications in electronic skin, flexible sensors, and human-machine interfaces.
ADVANCED FUNCTIONAL MATERIALS
(2023)
Article
Biochemistry & Molecular Biology
Li Zhong, Yuhui Zhang, Fei Liu, Luzhen Wang, Qian Feng, Chuchu Chen, Zhaoyang Xu
Summary: By regulating the internal structure of the hydrogel through pre-stretching synergistic ion crosslinking, a carboxymethyl cellulose-based double network oriented hydrogel similar to muscle was constructed, which significantly improved its mechanical and conductive properties. The assembled hydrogel sensors can monitor both simple and complex movements, making them potentially valuable in fields such as flexible wearables, intelligent strain sensing, and soft robots.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2023)
Article
Engineering, Manufacturing
Zixuan Zhou, Kehan Liu, Ziyue Ban, Weizhong Yuan
Summary: In this study, an anti-freezing and anti-drying organic hydrogel with high transparency, stretchability, adhesion, and self-healing abilities was designed. It not only exhibited excellent sensing performance but also served as a self-powered device, capable of recognizing the movement direction of objects and achieving sensor visualization.
COMPOSITES PART A-APPLIED SCIENCE AND MANUFACTURING
(2022)
Article
Chemistry, Applied
Jianquan Hu, Yinglong Wu, Qian Yang, Quanwei Zhou, Lanfeng Hui, Zhong Liu, Feng Xu, Dayong Ding
Summary: Ionic conductive hydrogels reinforced with cellulose nanofibrils and ZnSO4 were successfully designed through a simple method without soaking process. The hydrogels showed excellent mechanical properties and ionic conductivity, while the integrated sensor demonstrated outstanding performance in human motion monitoring.
CARBOHYDRATE POLYMERS
(2022)
Article
Chemistry, Physical
Juan Zeng, Hao Chen, Liubing Dong, Lu Wei, Xin Guo
Summary: In this study, a new type of anti-freezing hydrogel electrolyte was proposed by adding zwitterionic proline, which enables high ionic conductivity in hydrogel electrolytes at subzero temperatures. The unique structure of the proline electrolytes leads to strong hydration, ionic interactions, and low self-associations, resulting in excellent performance at low temperatures. The proline hydrogel electrolytes show high ionic conductivity and good low-temperature adaptability, making them suitable for anti-freezing energy storage devices.
JOURNAL OF COLLOID AND INTERFACE SCIENCE
(2023)
Article
Chemistry, Physical
Qunfeng Chen, Binbin Cheng, Zequn Wang, Xuhui Sun, Yang Liu, Haodong Sun, Jianwei Li, Lihui Chen, Xuhai Zhu, Liulian Huang, Yonghao Ni, Meng An, Jianguo Li
Summary: Excellent mechanical strength and conductivity are achieved in a cellulose ionogel via ZnCl2 doping. The Zn2+-cellulose engineering strategy produces a confined nanostructure that supports efficient transport of small anions and allows the ionogel to convert waste heat into electricity. This ion-molecular engineering strategy offers unprecedented freedom for developing adaptable gel materials.
JOURNAL OF MATERIALS CHEMISTRY A
(2023)
Article
Electrochemistry
Juyoung Moon, Juyun Lee, Yun Chan Kang, Jong Hak Kim, Jung Tae Park, Seon Joon Kim
Summary: The ionic conductivity of organohydrogel electrolytes was improved by using ionophilic MXene as a nanofiller, which exhibited strong affinity for Li+ ions and good dispersibility in water/glycerol. The MXene/poly(vinyl alcohol) organohydrogel electrolyte-based supercapacitors showed high gravimetric capacitance, wide potential window, and favorable post-freezing recyclability.
ELECTROCHIMICA ACTA
(2023)
Article
Polymer Science
Mingkai Yan, Xiaoyu Li, Hailan Lian
Summary: In this study, a natural deep eutectic solvent (NDES) was prepared using glycerin and organic choline chloride, and a starch/NDES ionic gel was synthesized through in situ free radical polymerization with starch as the reinforcement. The starch/NDES ionic gel exhibited excellent mechanical properties, self-recovery performance, thermal stability, frost resistance, and conductivity. It also showed potential as a strain sensor for monitoring grasping motion. This research provides a new green method for designing electronic products such as electronic skin.
JOURNAL OF APPLIED POLYMER SCIENCE
(2022)
Article
Chemistry, Multidisciplinary
Chuanwei Lu, Xinyu Wang, Yi Shen, Chunpeng Wang, Jifu Wang, Qiang Yong, Fuxiang Chu
Summary: This study reports a novel strategy to construct a liquid-free cellulose-derived ionic conductive elastomer, which is successfully applied in wearable sensors and triboelectric nanogenerators. The dual-crosslinking network of the elastomer improves its mechanical strength and toughness, and the cellulose contributes to a dense hydrogen bond crosslinking network, enhancing recyclability and solvent resistance. The ionic conductive elastomer demonstrates reliable sensing and energy harvesting performance, even after recycling, exposure to organic solvents, or extreme temperatures.
ADVANCED FUNCTIONAL MATERIALS
(2022)
Article
Nanoscience & Nanotechnology
Wenlian Qiu, Changgeng Zhang, Guoqing Chen, He Zhu, Qi Zhang, Shiping Zhu
Summary: A synthesized organohydrogel with ionic conductive and mechanochromic properties, known as I-skin, demonstrates high sensitivity in sensing and visualizing mechanical stimuli. It has applications in wearable devices and soft robotics, providing injury visualization and damage warning functions.
ACS APPLIED MATERIALS & INTERFACES
(2021)
Article
Chemistry, Applied
Yang Zou, Pengxiang Wang, Zhishui Fan, Xianxi Li, Shaokang Fang, Yue Yu, Hong Zhang, Yumei Gong, Yuanfa Liu, Jing Guo
Summary: This article introduces an ionic organohydrogel with high strength, high toughness, stretchability, frost resistance, and ionic conductivity. The organohydrogel can be used as a wire to light up LEDs and as a touch screen pen for electronic screen painting. Additionally, it is highly sensitive to hand movements and can serve as a path for flexible mechanical sensors. This new organohydrogel has potential applications in antifreeze materials and multifunctional sensors.
REACTIVE & FUNCTIONAL POLYMERS
(2022)
Review
Chemistry, Applied
Xingran Kou, Dongdong Su, Fei Pan, Xiwei Xu, Qingran Meng, Qinfei Ke
Summary: This review provides a systematic discussion of the application of molecular dynamics (MD) simulations in aroma compounds (ACs)/cyclodextrins (CDs) inclusion complexes (ICs). It covers the establishment of the simulation process, parameter selection, model evaluation, and various application cases, summarizing the major achievements and challenges of this method.
CARBOHYDRATE POLYMERS
(2024)
Review
Chemistry, Applied
Haoyu Yu, Quanbin Zhang, Ammad Ahmad Farooqi, Jing Wang, Yang Yue, Lihua Geng, Ning Wu
Summary: Brown algae are rich in fucoidan, which has been found to have anti-cancer and anti-metastasis effects. Fucoidan inhibits tumor cell growth, proliferation, and metastasis, and also promotes immune responses in the tumor microenvironment.
CARBOHYDRATE POLYMERS
(2024)
Review
Chemistry, Applied
Liang Dong, Yanan Li, Hailin Cong, Bing Yu, Youqing Shen
Summary: Gene therapy is a revolutionary treatment that requires suitable vectors for protecting and releasing exogenous nucleic acids in target cells. Chitosan, as a non-viral vector, has gained attention due to its good biocompatibility and ability to load large amounts of nucleic acids. This paper summarizes the potential of chitosan and its derivatives as gene delivery vector materials, discusses factors influencing transfection efficiency, performance evaluation, ways to optimize infectious efficiency, and current research development directions. It also provides an outlook on the future prospects of chitosan.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Ana Iglesias-Mejuto, Beatriz Magarinos, Tania Ferreira-Goncalves, Ricardo Starbird-Perez, Carmen Alvarez-Lorenzo, Catarina Pinto Reis, Ines Ardao, Carlos A. Garcia-Gonzalez
Summary: This study developed a novel processing strategy to manufacture drug-loaded and personalized aerogels with nanostructures. The aerogels demonstrated bioactivity and antimicrobial effects, promoting bone regeneration and preventing infections in bone tissue engineering.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Zhenxu Shi, Dimei Yang, Yan Zhou, Xinyu Chen, Lin Gan, Jin Huang
Summary: This study proposes a micro-assembly method to improve the photoluminescent properties of crystalline cellulose nanocrystals (CNCs) by organizing them within a sub-micrometer-sized metal-organic framework and coating with TiO2. The TiO2 coating prevents CNC assembly breakdown and allows information to be revealed using screenprinted labels for anti-counterfeiting purposes.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Xuejiao Liu, Bin Fu, Jierong Chen, Zhenyu Sun, Dongdong Zheng, Zhonghua Li, Bing Gu, Ying Zhang, Haojie Lu
Summary: Liver disease is a major cause of global mortality, and identifying biomarkers for diagnosing its progression is crucial for improving outcomes. Targeted mass spectrometry is a powerful tool for verifying biomarker candidates and clinical applications, particularly for glycoproteins translation. However, the limitation of analyzing only one sample per run has become apparent. In this study, a high-throughput intact N-glycopeptides quantification strategy was developed, allowing the validation of 20 samples per run with an average analysis time of 3 minutes per sample. The strategy was applied in a cohort of 461 serum samples and identified a panel of 10 IgG N-glycopeptides that have strong clinical utility in evaluating the severity of liver disease.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Qian Wang, Hao Jiang, Hongli Zhang, Weiqiao Lu, Xiao Wang, Wenfeng Xu, Jia Li, Youjing Lv, Guoyun Li, Chao Cai, Guangli Yu
Summary: This study proposes a novel strategy of antibody-beta-glucan conjugates (AGC) to enhance the antitumor immune response to immune checkpoint blockade (ICB) therapy. AGC demonstrated powerful tumor suppression and promoted interaction between tumor cells and dendritic cells (DCs), thereby enhancing immunotherapeutic benefits.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Chaeyeon Lee, Sojeong Lee, Sang Wook Kang
Summary: The study aims to enhance the properties of porous membranes by addressing the limitations associated with phase separation. By using cellulose acetate and citric acid, the researchers were able to fabricate membranes with improved mechanical strength and thermal stability. The cross-linking effect of citric acid resulted in a more uniform pore structure and higher porosity.
CARBOHYDRATE POLYMERS
(2024)
Review
Chemistry, Applied
Tejaswini Kolipaka, Giriraj Pandey, Noella Abraham, Dadi A. Srinivasarao, Rajeev Singh Raghuvanshi, P. S. Rajinikanth, Vidya Tickoo, Saurabh Srivastava
Summary: This review focuses on the design and application of polysaccharide-based hydrogel wound dressings, highlighting aspects such as biocompatibility, biodegradability, drug entrapment, moisturizing ability, swelling, and mechanical properties. Additionally, various crosslinking methods and recent developments in stimuli-responsive hydrogels are discussed.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Anqi Xu, Nan Zhang, Shixing Su, Hongyu Shi, Daoqiang Lu, Xifeng Li, Xin Zhang, Xin Feng, Zhuohua Wen, Gengwu Ma, Mengshi Huang, Chi Huang, Yuqi Hu, Hao Yuan, Qinwen Liu, Daogang Guan, Jun Wang, Chuanzhi Duan
Summary: The study presents a one-pot radical polymerization method to fabricate a hydrogel with adhesive properties, which can effectively treat bacterial-infected diabetic wounds and accelerate wound healing.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Montarop Yamabhai, Munthipha Khamphio, Thae Thae Min, Chai Noy Soem, Nguyen Cao Cuong, Waheni Rizki Aprilia, Krisanai Luesukprasert, Karsidete Teeranitayatarn, Atthaphon Maneedaeng, Tina R. Tuveng, Silje B. Lorentzen, Simen Antonsen, Paiboon Jitprasertwong, Vincent G. H. Eijsink
Summary: The study investigates the bioconversion of chitosan into soluble anti-inflammatory chitosan oligosaccharides (CHOS) using an enzyme. The results show that the generated CHOS have anti-inflammatory activity, but the magnitude of the activity depends on the substrate and production process. Different methods of dissolving chitosan also affect the properties of CHOS. The study highlights the importance of quality assurance in CHOS preparations.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Wen Cao, Jiangping Wu, Xinya Zhao, Zixu Li, Jie Yu, Taili Shao, Xuefeng Hou, Lutan Zhou, Chunfei Wang, Guodong Wang, Jun Han
Summary: In this study, a water-soluble polysaccharide (PLP1) was successfully isolated and purified from Pueraria lobata. It was found that PLP1 was composed of specific glycosidic units and exhibited a better free radical-scavenging ability. Moreover, PLP1 effectively protected the liver against acute alcoholic liver disease (ALD) in mice.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Ya Su, Yaqian Liu, Xueyan Hu, Yueqi Lu, Jinyuan Zhang, Wenbo Jin, Wang Liu, Yan Shu, Yuen Yee Cheng, Wenfang Li, Yi Nie, Bo Pan, Kedong Song
Summary: A 3D printed scaffold based on carbon dots-curcumin nano-drug release has been developed for drug delivery after breast cancer surgery. The scaffold showed effective inhibition of tumor growth, antibacterial activity, and promotion of wound healing, making it a promising approach for preventing tumor recurrence.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Ekaterina Sokolova, Diane Jouanneau, Antonin Chevenier, Murielle Jam, Nathalie Desban, Pierre Colas, Elizabeth Ficko-Blean, Gurvan Michel
Summary: Carrageenans, a compound synthesized in red algae, have various biological properties and are valuable in the pharmaceutical and cosmetic industries. Their fine structure affects wound healing, oxidative processes, hemostasis, and inflammation. Enzymatic modification of carrageenans produces oligosaccharides that bind to natural human serum antibodies and specific antibodies, showing potential for therapeutic applications.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Yan Shi, Miao Yu, Kaijin Qiu, Tiantian Kong, Chunjing Guo, Wenxue Zhang, Daquan Chen, Ming Kong
Summary: In this study, functionalized transfersomes were developed to co-deliver doxorubicin and 1MT towards primary tumors and tumor draining lymph nodes via transdermal administration using microneedles. The results showed that the nano-complexed microneedles exhibited a stronger suppression in tumor growth compared to the intravenous group.
CARBOHYDRATE POLYMERS
(2024)