Article
Oncology
Angela N. Giaquinto, Hyuna Sung, Kimberly D. Miller, Joan L. Kramer, Lisa A. Newman, Adair Minihan, Ahmedin Jemal, Rebecca L. Siegel
Summary: This article provides an update on female breast cancer statistics in the United States, including data on incidence, mortality, survival, and mammography screening. It shows that breast cancer incidence rates have increased over the past few decades, driven by localized-stage and hormone receptor-positive disease. However, breast cancer mortality rates have been steadily declining since 1989, although at a slower pace in recent years. Despite lower incidence rates, there remains a racial disparity in breast cancer mortality, with higher rates among Black women compared to White women.
CA-A CANCER JOURNAL FOR CLINICIANS
(2022)
Article
Multidisciplinary Sciences
Shadi Rahimzadeh, Beata Burczynska, Alireza Ahmadvand, Ali Sheidaei, Sara Khademioureh, Forough Pazhuheian, Sahar Saeedi Moghaddam, James Bentham, Farshad Farzadfar, Mariachiara Di Cesare
Summary: The study found that breast cancer incidence in Iran has been increasing over time, with higher rates in wealthier provinces and a more significant decrease in mortality rates in those provinces. Additionally, the relative breast cancer mortality decreased by 16.7% in the wealthiest provinces compared to 10.8% in the poorest provinces.
Article
Medicine, General & Internal
Urgena Maharjan, Joonas H. Kauppila
Summary: This study assessed the registry coverage for gastric cancer in FCR and HILMO in Finland. The results showed that gastric cancer was well captured by both registries, but there was a decrease in the proportion of cases reported to FCR over time. The completeness of FCR was estimated at 87% and for HILMO, it was 92.7%. Death due to gastric cancer was most common in those with gastric cancer reported in both registries.
Article
Oncology
Megan Hoopes, Robert Voss, Heather Angier, Miguel Marino, Teresa Schmidt, Jennifer E. DeVoe, Jeffrey Soule, Nathalie Huguet
Summary: The study found that nearly half of cancer patients identified in state cancer registries were missing cancer documentation in the Electronic Health Records (EHRs) of community health centers (CHCs). The agreement between EHR and cancer registry data was moderate overall, but varied by cancer site.
JNCI-JOURNAL OF THE NATIONAL CANCER INSTITUTE
(2021)
Article
Multidisciplinary Sciences
Markus Jaeckel, Nico Aicher, Jonathan Rilinger, Xavier Bemtgen, Eugen Widmeier, Tobias Wengenmayer, Daniel Duerschmied, Paul Marc Biever, Peter Stachon, Christoph Bode, Dawid Leander Staudacher
Summary: This study found a high prevalence of delirium in AKI patients in the ICU, with independent predictors including age, psychiatric disease, alcohol abuse, mechanical ventilation, severe shock, and AKI stage II/III. The duration of ICU stay correlated with higher stages of AKI and the presence of delirium in AKI patients.
SCIENTIFIC REPORTS
(2021)
Article
Genetics & Heredity
Leila Dorling, Sara Carvalho, Jamie Allen, Michael T. Parsons, Cristina Fortuno, Anna Gonzalez-Neira, Stephan M. Heijl, Muriel A. Adank, Thomas U. Ahearn, Irene L. Andrulis, Paivi Auvinen, Heiko Becher, Matthias W. Beckmann, Sabine Behrens, Marina Bermisheva, Natalia V. Bogdanova, Stig E. Bojesen, Manjeet K. Bolla, Michael Bremer, Ignacio Briceno, Nicola J. Camp, Archie Campbell, Jose E. Castelao, Jenny Chang-Claude, Stephen J. Chanock, Georgia Chenevix-Trench, J. Margriet Collee, Kamila Czene, Joe Dennis, Thilo Dork, Mikael Eriksson, D. Gareth Evans, Peter A. Fasching, Jonine Figueroa, Henrik Flyger, Marike Gabrielson, Manuela Gago-Dominguez, Montserrat Garcia-Closas, Graham G. Giles, Gord Glendon, Pascal Guenel, Melanie Gundert, Andreas Hadjisavvas, Eric Hahnen, Per Hall, Ute Hamann, Elaine F. Harkness, Mikael Hartman, Frans B. L. Hogervorst, Antoinette Hollestelle, Reiner Hoppe, Anthony Howell, Anna Jakubowska, Audrey Jung, Elza Khusnutdinova, Sung-Won Kim, Yon-Dschun Ko, Vessela N. Kristensen, Inge M. M. Lakeman, Jingmei Li, Annika Lindblom, Maria A. Loizidou, Artitaya Lophatananon, Jan Lubinski, Craig Luccarini, Michael J. Madsen, Arto Mannermaa, Mehdi Manoochehri, Sara Margolin, Dimitrios Mavroudis, Roger L. Milne, Nur Aishah Mohd Taib, Kenneth Muir, Heli Nevanlinna, William G. Newman, Jan C. Oosterwijk, Sue K. Park, Paolo Peterlongo, Paolo Radice, Emmanouil Saloustros, Elinor J. Sawyer, Rita K. Schmutzler, Mitul Shah, Xueling Sim, Melissa C. Southey, Harald Surowy, Maija Suvanto, Ian Tomlinson, Diana Torres, Therese Truong, Christi J. van Asperen, Regina Waltes, Qin Wang, Xiaohong R. Yang, Paul D. P. Pharoah, Marjanka K. Schmidt, Javier Benitez, Bas Vroling, Alison M. Dunning, Soo Hwang Teo, Anders Kvist, Miguel de la Hoya, Peter Devilee, Amanda B. Spurdle, Maaike P. G. Vreeswijk, Douglas F. Easton
Summary: The study found that certain rare missense variants in ATM, BRCA1, BRCA2, and CHEK2 genes may increase the risk of developing breast cancer, while missense variants in the PALB2 gene are less likely to be associated with risk.
Article
Gastroenterology & Hepatology
Tomoyuki Satake, Chigusa Morizane, Ryoko Rikitake, Takahiro Higashi, Takuji Okusaka, Akira Kawai
Summary: This is the first comprehensive report on the epidemiological status of rare HBP tumors in Japan using population-based NCR data. The results show that the proportions of these rare tumors differ in different locations, with a higher proportion in male patients and varying rates of late-stage diagnosis.
JOURNAL OF GASTROENTEROLOGY
(2022)
Article
Oncology
Angel Borque-Fernando, Josep Maria Gaya, Luis Mariano Esteban-Escano, Juan Gomez-Rivas, Rodrigo Garcia-Baquero, Fernando Agreda-Castaneda, Andrea Gallioli, Paolo Verri, Francisco Javier Ortiz-Vico, Balig Fawwaz Amir-Nicolau, Ignacio Osman-Garcia, Pedro Gil-Martinez, Miguel Arrabal-Martin, Alvaro Gomez-Ferrer Lozano, Felix Campos-Juanatey, Felix Guerrero-Ramos, Jose Rubio-Briones
Summary: This study provides an updated outlook on the epidemiology, risk factors, clinical presentation, and treatment of penile cancer in Spain. The results emphasize the need for referral centers and standardized diagnostic pathways for optimal management.
Article
Oncology
Linda A. Liang, Ying-Ju Tseng, Luana F. Tanaka, Stefanie J. Klug
Summary: Increasing survival rates for colorectal cancer (CRC) means more survivors are developing second primary cancer (SPC), particularly in younger populations. This study estimated the incidence and risk factors of SPC in CRC survivors. The study found that CRC survivors had a higher risk of developing other cancers compared to the general population, with increased risks in the digestive and urinary systems, as well as reproductive organs. Younger individuals (<50 years) had a significantly higher incidence of SPC, with primary tumor characteristics such as right-sided cancer and smaller tumor size associated with increased risk. Treatment and risk of SPC differed between colon cancer and rectal cancer. The findings suggest the need for targeted surveillance for CRC survivors.
INTERNATIONAL JOURNAL OF CANCER
(2023)
Article
Oncology
Francesco Giusti, Carmen Martos, Raquel Negrao Carvalho, Liesbet Van Eycken, Otto Visser, Manola Bettio
Summary: Population-based Cancer Registries (PBCRs) play a crucial role in collecting high-quality data for monitoring cancer burden, planning cancer control activities, and conducting research. This article evaluates the quality of PBCRs data collected in a specific data call in 2015.
FRONTIERS IN ONCOLOGY
(2023)
Article
Multidisciplinary Sciences
Shaohua Lyu, Claire Shuiqing Zhang, Anthony Lin Zhang, Jingbo Sun, Charlie Changli Xue, Xinfeng Guo
Summary: This real-world observational study aims to gather practice-based evidence of effects and safety of Chinese herbal medicine (CHM) for migraine, exploring factors related to clinical outcomes. The study will provide comprehensive evidence of CHM for migraine in the context of evidence-based practice and integrate Chinese medicine diagnostic procedures, patients' preferences, and matters relevant to clinical decision making.
Article
Multidisciplinary Sciences
Mesnad Alyabsi, Majed Ramadan, Mohammed Algarni, Kanan Alshammari, Abdul Rahman Jazieh
Summary: A study in Saudi Arabia found that unmarried CRC patients were more likely to be diagnosed at a late stage and had a higher risk of death due to CRC compared to married patients. Future interventions should focus on early cancer screening and survivorship programs for the unmarried population to improve cancer outcomes.
SCIENTIFIC REPORTS
(2021)
Article
Oncology
Sabrina Wang, Farhana Sultana, Anne Kavanagh, Carolyn Nickson, Amalia Karahalios, Lyle C. Gurrin, Dallas R. English
Summary: This study aimed to quantify the impact of mammographic screening on breast cancer mortality and overdiagnosis. The results showed that women who participate in Australia's national screening program have lower breast cancer mortality, but some screen-detected cancers may be overdiagnosed.
Article
Public, Environmental & Occupational Health
Paddy Ssentongo, John S. Oh, Forster Amponsah-Manu, William Wong, Xavier Candela, Yubraj Acharya, Anna E. Ssentongo, Daleela G. Dodge
Summary: This study explored the factors influencing mortality in breast cancer in the Eastern region of Ghana and found that the survival rate in this area is low. Despite success in reducing mortality in breast cancer in northern Africa, sub-Saharan African countries still face poor outcomes. Late-stage presentation and limited accuracy in diagnosis are the main contributors to the low survival rate.
FRONTIERS IN PUBLIC HEALTH
(2022)
Article
Health Care Sciences & Services
Enke Baldini, Augusto Lauro, Domenico Tripodi, Daniele Pironi, Maria Ida Amabile, Iulia Catalina Ferent, Eleonora Lori, Federica Gagliardi, Maria Irene Bellini, Flavio Forte, Patrizia Pacini, Vito Cantisani, Vito D'Andrea, Salvatore Sorrenti, Salvatore Ulisse
Summary: Epidemiological studies have shown an association between thyroid diseases and extra-thyroidal malignancies, particularly breast cancer. Patients with autoimmune thyroiditis have an increased risk of breast cancer, although the risk is lower for those who are thyroid autoantibody-positive. The molecular links between thyroid autoimmunity and breast cancer remain uncertain.
JOURNAL OF PERSONALIZED MEDICINE
(2022)
Letter
Oncology
Mya L. Roberson, Paula D. Strassle, Luther-King Okunade Fasehun, Daniel O. Erim, E. Gene Deune, Adeyemi A. Ogunleye
Article
Dermatology
Michael J. Duplisea, Mya L. Roberson, Lori Chrisco, Paula D. Strassle, Felicia N. Williams, Carolyn M. Ziemer
Summary: The ABCD-10 model was proposed as an alternative to SCORTEN for predicting in-hospital mortality in patients with SJS/TEN, but in a study at a large tertiary burn center, SCORTEN was found to be a better predictor of inpatient mortality. Both models showed good discrimination, but SCORTEN had better calibration for predicting mortality in this patient cohort.
JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY
(2021)
Article
Pediatrics
Adesola C. Akinkuotu, Mya Roberson, Paula D. Strassle, Michael R. Phillips, Sean E. McLean, Andrea Hayes-Jordan
Summary: This study evaluated factors related to early inguinal hernia repair (IHR) in premature infants. The results showed that early IHR was more commonly performed in non-Hispanic White, female neonates, and at urban teaching hospitals. Patient race and hospital type were determinants of early IHR in premature neonates.
JOURNAL OF PEDIATRIC SURGERY
(2022)
Article
Surgery
Kathleen A. Iles, Madeline Thornton, Jihye Park, Mya Roberson, Philip M. Spanheimer, David W. Ollila, Kristalyn Gallagher
Summary: The study compared treatment methods and outcomes of patients diagnosed with HR+/HER2- breast cancer in 2019 and 2020, finding that more patients in 2020 utilized neoadjuvant endocrine therapy as bridging therapy. The impact on clinical and pathologic staging was similar across different treatment approaches, but neoadjuvant endocrine therapy was shown to optimize healthcare utilization.
Article
Oncology
Mya L. Roberson, Hazel B. Nichols, Andrew F. Olshan, Stephanie B. Wheeler, Katherine E. Reeder-Hayes, Whitney R. Robinson
Summary: This study examines trends in surgical treatment of breast cancer in a racially diverse state in the Southeastern US, focusing on age, rurality, and Black women. The results show a decline in mastectomy rates and an increase in breast-conserving surgery rates between 2003 and 2016. These trends were consistent among different age groups, Black women, and women residing in rural areas.
BREAST CANCER RESEARCH AND TREATMENT
(2022)
Editorial Material
Oncology
L. Alicia Best, L. Mya Roberson, J. Jesse Plascak, E. Caryn Peterson, R. Charles Rogers, A. Theresa Hastert, Yamile Molina
CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION
(2022)
Article
Oncology
Kathleen Iles, Mya L. Roberson, Philip Spanheimer, Kristalyn Gallagher, David W. Ollila, Paula D. Strassle, Stephanie Downs-Canner
Summary: This analysis examines the use of Oncotype DX (ODX) testing and its association with adjuvant chemotherapy (AC) receipt in breast cancer patients. The study shows that older patients are less likely to receive ODX testing, while nodal positivity increases its use. High ODX recurrence score (RS) is associated with increased mortality, especially among younger node-negative women.
Editorial Material
Dermatology
Mya L. Roberson, Adewole S. Adamson, Kanade Shinkai
Letter
Oncology
Sonya Reid, Mya L. Roberson, Kenna Koehler, Tiana Shah, Anne Weidner, Jennifer G. Whisenant, Tuya Pal
Summary: This case series study investigates the differences in surgical treatment between adult females with invasive breast cancer who have pathogenic or likely pathogenic variants in genes with high vs moderate breast cancer penetrance.
Editorial Material
Oncology
Elle Lett, Joannie M. Ivory, Mya L. Roberson
Summary: Transgender patients are marginalized and current oncology standards need improvement. This Comment highlights the need for inclusive and specific practices in cancer care for transgender populations while identifying evidence gaps.
NATURE REVIEWS CLINICAL ONCOLOGY
(2023)
Editorial Material
Dermatology
Amy J. McMichael, Mya L. Roberson
Editorial Material
Dermatology
Mya L. Roberson, Kanade Shinkai
Article
Health Care Sciences & Services
Joshua Woods, Shekinah N. C. Elmore, Lesley Glenn, Julia Maues, Deltra James, Mya L. Roberson
Summary: The COVID-19 pandemic has had a significant impact on the care of patients with metastatic breast cancer. The study found that there were varying preferences for telehealth, disruptions in care, and a shift towards virtual social care.
JOURNAL OF PATIENT EXPERIENCE
(2023)
Letter
Health Care Sciences & Services
Mya L. Roberson, Nana Addo Padi-Adjirackor, Gillian Hooker, Tuya Pal
Summary: This study examines the prevalence of out-of-pocket costs for cancer-related genetic counseling services in the United States.