Characterisation of agonist signalling profiles and agonist‐dependent antagonism at PACAP‐responsive receptors: Implications for drug discovery
出版年份 2021 全文链接
标题
Characterisation of agonist signalling profiles and agonist‐dependent antagonism at PACAP‐responsive receptors: Implications for drug discovery
作者
关键词
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出版物
BRITISH JOURNAL OF PHARMACOLOGY
Volume 179, Issue 3, Pages 435-453
出版商
Wiley
发表日期
2021-10-08
DOI
10.1111/bph.15700
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注意:仅列出部分参考文献,下载原文获取全部文献信息。- THE CONCISE GUIDE TO PHARMACOLOGY 2021/22: Enzymes
- (2021) Stephen PH Alexander et al. BRITISH JOURNAL OF PHARMACOLOGY
- THE CONCISE GUIDE TO PHARMACOLOGY 2021/22: G protein‐coupled receptors
- (2021) Stephen PH Alexander et al. BRITISH JOURNAL OF PHARMACOLOGY
- Cryo-EM structures of PAC1 receptor reveal ligand binding mechanism
- (2020) Jia Wang et al. CELL RESEARCH
- PAC1 receptor blockade reduces central nociceptive activity
- (2020) Jan Hoffmann et al. PAIN
- Two-hour infusion of vasoactive intestinal polypeptide induces delayed headache and extracranial vasodilation in healthy volunteers
- (2020) Lanfranco Pellesi et al. CEPHALALGIA
- Agonist bias and agonist‐dependent antagonism at corticotrophin releasing factor receptors
- (2020) Zoe Tasma et al. Pharmacology Research & Perspectives
- Plasma levels of vasoactive neuropeptides in pediatric patients with migraine during attack and attack-free periods
- (2020) Fatma Hanci et al. CEPHALALGIA
- Targeting pituitary adenylate cyclase-activating polypeptide (PACAP) with monoclonal antibodies in migraine prevention: a brief review
- (2020) Cecilia Rustichelli et al. EXPERT OPINION ON INVESTIGATIONAL DRUGS
- Antagonism of CGRP Signaling by Rimegepant at Two Receptors
- (2020) Kylie S. Pan et al. Frontiers in Pharmacology
- A phase 2, randomized, double-blind, placebo-controlled trial of AMG 301, a pituitary adenylate cyclase-activating polypeptide PAC1 receptor monoclonal antibody for migraine prevention
- (2020) Messoud Ashina et al. CEPHALALGIA
- Pharmacologic Characterization of ALD1910, a Potent Humanized Monoclonal Antibody against the Pituitary Adenylate Cyclase Activating Peptide
- (2019) Cristina Moldovan Loomis et al. JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS
- PACAP27 induces migraine-like attacks in migraine patients
- (2019) Hashmat Ghanizada et al. CEPHALALGIA
- Multiplexed analysis of the secretin-like GPCR-RAMP interactome
- (2019) Emily Lorenzen et al. Science Advances
- Experimental design and analysis and their reporting II: updated and simplified guidance for authors and peer reviewers
- (2018) Michael J Curtis et al. BRITISH JOURNAL OF PHARMACOLOGY
- G Protein-Coupled Receptor Endosomal Signaling and Regulation of Neuronal Excitability and Stress Responses: Signaling Options and Lessons From the PAC1 Receptor
- (2016) Victor May et al. JOURNAL OF CELLULAR PHYSIOLOGY
- Lost in Translation: CRF1 Receptor Antagonists and Addiction Treatment
- (2016) Yavin Shaham et al. NEUROPSYCHOPHARMACOLOGY
- Vasoactive Intestinal Peptide modulates trophoblast-derived cell line function and interaction with phagocytic cells through autocrine pathways
- (2016) Daiana Vota et al. Scientific Reports
- Investigation of the pathophysiological mechanisms of migraine attacks induced by pituitary adenylate cyclase-activating polypeptide-38
- (2014) Faisal Mohammad Amin et al. BRAIN
- PACAP receptor pharmacology and agonist bias: analysis in primary neurons and glia from the trigeminal ganglia and transfected cells
- (2013) C S Walker et al. BRITISH JOURNAL OF PHARMACOLOGY
- Alterations in PACAP-38-like immunoreactivity in the plasma during ictal and interictal periods of migraine patients
- (2013) Bernadett Tuka et al. CEPHALALGIA
- PACAP induces the dimerization of PAC1 on the nucleus associated with the cAMP increase in the nucleus
- (2013) Rongjie Yu et al. NEUROSCIENCE LETTERS
- Alternative Splicing of the Pituitary Adenylate Cyclase-Activating Polypeptide Receptor PAC1: Mechanisms of Fine Tuning of Brain Activity
- (2013) Janna Blechman et al. Frontiers in Endocrinology
- Pharmacology and functions of receptors for vasoactive intestinal peptide and pituitary adenylate cyclase-activating polypeptide: IUPHAR Review 1
- (2012) Anthony J Harmar et al. BRITISH JOURNAL OF PHARMACOLOGY
- New concepts in pharmacological efficacy at 7TM receptors: IUPHAR Review 2
- (2012) Terry Kenakin BRITISH JOURNAL OF PHARMACOLOGY
- Receptor activity modifying proteins (RAMPs) interact with the VPAC2receptor and CRF1receptors and modulate their function
- (2012) D Wootten et al. BRITISH JOURNAL OF PHARMACOLOGY
- Consequences of splice variation on Secretin family G protein-coupled receptor function
- (2011) Sebastian GB Furness et al. BRITISH JOURNAL OF PHARMACOLOGY
- Protective Effects of Pituitary Adenylate Cyclase-Activating Polypeptide (PACAP) Against Apoptosis
- (2011) Tommy Seaborn et al. CURRENT PHARMACEUTICAL DESIGN
- Pituitary Adenylate Cyclase-activating Polypeptide (PACAP)/PAC1HOP1 Receptor Activation Coordinates Multiple Neurotrophic Signaling Pathways
- (2010) Victor May et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Allostery at G Protein-Coupled Receptor Homo- and Heteromers: Uncharted Pharmacological Landscapes
- (2010) N. J. Smith et al. PHARMACOLOGICAL REVIEWS
- Alternative splicing of G protein-coupled receptors: physiology and pathophysiology
- (2009) Danijela Markovic et al. CELLULAR AND MOLECULAR LIFE SCIENCES
- PACAP38 induces migraine-like attacks in patients with migraine without aura
- (2008) Henrik Winther Schytz et al. BRAIN
- MAP kinase and pain
- (2008) Ru-Rong Ji et al. BRAIN RESEARCH REVIEWS
- Vasoactive Intestinal Peptide Causes Marked Cephalic Vasodilation, but does not Induce Migraine
- (2008) A Rahmann et al. CEPHALALGIA
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