Disorder-to-order transition of the amyloid-β peptide upon lipid binding

Energy Landscapes of Protein Aggregation and Conformation Switching in Intrinsically Disordered Proteins

(2021) Birgit Strodel   JOURNAL OF MOLECULAR BIOLOGY

Amyloid-β peptide dimers undergo a random coil to β-sheet transition in the aqueous phase but not at the neuronal membrane

(2021) Hebah Fatafta et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Amyloidogenic Intrinsically Disordered Proteins: New Insights into Their Self-Assembly and Their Interaction with Membranes

(2020) Federica Scollo et al.   Life-Basel

Lipid-Chaperone Hypothesis: A Common Molecular Mechanism of Membrane Disruption by Intrinsically Disordered Proteins

(2020) Michele F. Sciacca et al.   ACS Chemical Neuroscience

Amyloid aggregation simulations: challenges, advances and perspectives

(2020) Birgit Strodel   CURRENT OPINION IN STRUCTURAL BIOLOGY

Intrinsically Disordered Proteins in Chronic Diseases

(2019) Kulkarni et al.   Biomolecules

The Amyloid-β Oligomer Hypothesis: Beginning of the Third Decade

(2018) Erika N. Cline et al.   JOURNAL OF ALZHEIMERS DISEASE

Order-disorder transition of intrinsically disordered kinase inducible transactivation domain of CREB

(2018) Hao Liu et al.   JOURNAL OF CHEMICAL PHYSICS

Developing a molecular dynamics force field for both folded and disordered protein states

(2018) Paul Robustelli et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Aster Proteins Facilitate Nonvesicular Plasma Membrane to ER Cholesterol Transport in Mammalian Cells

(2018) Jaspreet Sandhu et al.   CELL

Phospholipids Critical Micellar Concentrations Trigger Different Mechanisms of Intrinsically Disordered Proteins Interaction with Model Membranes

(2018) Federica Scollo et al.   Journal of Physical Chemistry Letters

A Comprehensive Survey of the Roles of Highly Disordered Proteins in Type 2 Diabetes

(2017) Zhihua Du et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Phosphorylation-induced conformational dynamics in an intrinsically disordered protein and potential role in phenotypic heterogeneity

(2017) Prakash Kulkarni et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Lipid-assisted protein transport: A diffusion-reaction model supported by kinetic experiments and molecular dynamics simulations

(2016) Carmelo La Rosa et al.   JOURNAL OF CHEMICAL PHYSICS

Advances in the Simulation of Protein Aggregation at the Atomistic Scale

(2016) Martín Carballo-Pacheco et al.   JOURNAL OF PHYSICAL CHEMISTRY B

CHARMM36m: an improved force field for folded and intrinsically disordered proteins

(2016) Jing Huang et al.   NATURE METHODS

CHARMM-GUI Input Generator for NAMD, GROMACS, AMBER, OpenMM, and CHARMM/OpenMM Simulations Using the CHARMM36 Additive Force Field

(2015) Jumin Lee et al.   Journal of Chemical Theory and Computation

The triple power of D³: Protein intrinsic disorder in degenerative diseases

(2014) Vladimir Uversky   Frontiers in Bioscience-Landmark

Amyloid-Beta: A Crucial Factor in Alzheimer's Disease

(2014) Saeed Sadigh-Eteghad et al.   MEDICAL PRINCIPLES AND PRACTICE

Folding of an intrinsically disordered protein by phosphorylation as a regulatory switch

(2014) Alaji Bah et al.   NATURE

The Stress-response protein prostate-associated gene 4, interacts with c-Jun and potentiates its transactivation

(2013) Krithika Rajagopalan et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

A decade and a half of protein intrinsic disorder: Biology still waits for physics

(2013) Vladimir N. Uversky   PROTEIN SCIENCE

Cell cycle regulation by the intrinsically disordered proteins p21 and p27

(2012) Mi-Kyung Yoon et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

Development of the CHARMM Force Field for Lipids

(2011) R. W. Pastor et al.   Journal of Physical Chemistry Letters

Intrinsic disorder in proteins associated with neurodegenerative diseases

(2010) Vladimir et al.   Frontiers in Bioscience-Landmark

The culprit behind amyloid beta peptide related neurotoxicity in Alzheimer's disease: oligomer size or conformation?

(2010) Kerensa Broersen et al.   Alzheimers Research & Therapy

Cholesterol transport in steroid biosynthesis: Role of protein–protein interactions and implications in disease states

(2009) Malena B. Rone et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

Biophysical characterization of intrinsically disordered proteins

(2009) David Eliezer   CURRENT OPINION IN STRUCTURAL BIOLOGY

PACKMOL: A package for building initial configurations for molecular dynamics simulations

(2009) L. Martínez et al.   JOURNAL OF COMPUTATIONAL CHEMISTRY

Structures of β-Amyloid Peptide 1−40, 1−42, and 1−55—the 672−726 Fragment of APP—in a Membrane Environment with Implications for Interactions with γ-Secretase

(2009) Naoyuki Miyashita et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

The amyloid cascade hypothesis

(2008) Amos D. Korczyn   Alzheimers & Dementia

Amyloidogenesis of Natively Unfolded Proteins

(2008) Vladimir Uversky   Current Alzheimer Research

Role of intrinsically disordered protein regions/domains in transcriptional regulation

(2008) Anna S. Garza et al.   LIFE SCIENCES

Amyloid beta, mitochondrial dysfunction and synaptic damage: implications for cognitive decline in aging and Alzheimer's disease

(2008) P. Hemachandra Reddy et al.   TRENDS IN MOLECULAR MEDICINE