Synthesis of lathyrane diterpenoid nitrogen-containing heterocyclic derivatives and evaluation of their anti-inflammatory activities

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(2021) Jiajie Hou et al.   Nature Reviews Clinical Oncology

Inflammation and Depression: A Public Health Perspective

(2021) Alexander L. Chu et al.   BRAIN BEHAVIOR AND IMMUNITY

Anti-inflammatory Lathyrane Diterpenoids from Euphorbia lathyris

(2019) Cui-Yun Zhang et al.   JOURNAL OF NATURAL PRODUCTS

Anti-Inflammatory Properties of Plant Derived Natural Products – A Systematic Review

(2019) Iris Allijn et al.   CURRENT MEDICINAL CHEMISTRY

Non-acidic 1,3,4-trisubstituted-pyrazole derivatives as lonazolac analogs with promising COX-2 selectivity, anti-inflammatory activity and gastric safety profile

(2018) Khaled R.A. Abdellatif et al.   BIOORGANIC CHEMISTRY

Reactive Oxygen Species in Metabolic and Inflammatory Signaling

(2018) Steven J. Forrester et al.   CIRCULATION RESEARCH

The dual role of ROS in autoimmune and inflammatory diseases: Evidence from preclinical models

(2018) Markus H. Hoffmann et al.   FREE RADICAL BIOLOGY AND MEDICINE

Furoxans (Oxadiazole-4N-oxides) with Attenuated Reactivity are Neuroprotective, Cross the Blood Brain Barrier, and Improve Passive Avoidance Memory

(2018) Austin Horton et al.   JOURNAL OF MEDICINAL CHEMISTRY

Euphorbia factor L2 alleviates lipopolysaccharide-induced acute lung injury and inflammation in mice through the suppression of NF-κB activation

(2018) Qiuping Zhang et al.   BIOCHEMICAL PHARMACOLOGY

Reactive oxygen species (ROS) in macrophage activation and function in diabetes

(2018) Erika Rendra et al.   IMMUNOBIOLOGY

Lathyrol Diterpenes as Modulators of P-Glycoprotein Dependent Multidrug Resistance: Structure–Activity Relationship Studies on Euphorbia Factor L3 Derivatives

(2015) Wei Jiao et al.   JOURNAL OF MEDICINAL CHEMISTRY

Design, Synthesis, X-ray Crystallographic Analysis, and Biological Evaluation of Thiazole Derivatives as Potent and Selective Inhibitors of Human Dihydroorotate Dehydrogenase

(2015) Junsheng Zhu et al.   JOURNAL OF MEDICINAL CHEMISTRY

Epoxylathyrol Derivatives: Modulation of ABCB1-Mediated Multidrug Resistance in Human Colon Adenocarcinoma and Mouse T-Lymphoma Cells

(2015) Ana M. Matos et al.   JOURNAL OF NATURAL PRODUCTS

Inhibition of Group IVA Cytosolic Phospholipase A2 by Thiazolyl Ketones in Vitro, ex Vivo, and in Vivo

(2014) George Kokotos et al.   JOURNAL OF MEDICINAL CHEMISTRY

Novel Nitric Oxide-Releasing Derivatives of Brusatol as Anti-Inflammatory Agents: Design, Synthesis, Biological Evaluation, and Nitric Oxide Release Studies

(2014) Weibin Tang et al.   JOURNAL OF MEDICINAL CHEMISTRY

The Nrf2 regulatory network provides an interface between redox and intermediary metabolism

(2014) John D. Hayes et al.   TRENDS IN BIOCHEMICAL SCIENCES

Nitric Oxide: State of the Art in Drug Design

(2012) R.A.M. Serafim et al.   CURRENT MEDICINAL CHEMISTRY

Identification of 5-arylidene-4-thiazolidinone derivatives endowed with dual activity as aldose reductase inhibitors and antioxidant agents for the treatment of diabetic complications

(2011) Rosaria Ottanà et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Nitric oxide activates an Nrf2/sulfiredoxin antioxidant pathway in macrophages

(2011) Kahina Abbas et al.   FREE RADICAL BIOLOGY AND MEDICINE

Chemical and Pharmacological Research of the Plants in GenusEuphorbia

(2008) Qing-Wen Shi et al.   CHEMICAL REVIEWS