HDAC3 inhibitor suppresses endothelial-to-mesenchymal transition via modulating inflammatory response in atherosclerosis

Histone deacetylase 3 inhibition alleviates type 2 diabetes mellitus-induced endothelial dysfunction via Nrf2

(2021) Shuai Huang et al.   Cell Communication and Signaling

miR‐145 inhibits the proliferation and migration of vascular smooth muscle cells by regulating autophagy

(2020) Weirong Wang et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Pharmacological inhibition of histone deacetylase reduces NADPH oxidase expression, oxidative stress and the progression of atherosclerotic lesions in hypercholesterolemic apolipoprotein E-deficient mice; potential implications for human atherosclerosis

(2019) Simona-Adriana Manea et al.   Redox Biology

HDAC3 inhibition in diabetic mice may activate Nrf2 preventing diabetes-induced liver damage and FGF21 synthesis and secretion leading to aortic protection

(2018) Jian Zhang et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Reassessing endothelial-to-mesenchymal transition in cardiovascular diseases

(2018) Yan Li et al.   Nature Reviews Cardiology

Endothelial-to-mesenchymal transition: A novel therapeutic target for cardiovascular diseases

(2017) Ampadu O. Jackson et al.   TRENDS IN CARDIOVASCULAR MEDICINE

Corrigendum: Endothelial to mesenchymal transition is common in atherosclerotic lesions and is associated with plaque instability

(2017) Solene M. Evrard et al.   Nature Communications

In Brief: Endothelial-to-mesenchymal transition

(2016) Gonzalo Sanchez-Duffhues et al.   JOURNAL OF PATHOLOGY

High-Density Lipoproteins Reduce Endothelial-to-Mesenchymal TransitionSignificance

(2015) Frank Spillmann et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Endothelial-to-mesenchymal transition contributes to fibro-proliferative vascular disease and is modulated by fluid shear stress

(2015) Jan-Renier A.J. Moonen et al.   CARDIOVASCULAR RESEARCH

Endothelial-to-Mesenchymal Transition in Pulmonary Hypertension

(2015) B. Ranchoux et al.   CIRCULATION

Endothelial-to-mesenchymal transition drives atherosclerosis progression

(2015) Pei-Yu Chen et al.   JOURNAL OF CLINICAL INVESTIGATION

The Endothelial-mesenchymal Transition in Systemic Sclerosis Is Induced by Endothelin-1 and Transforming Growth Factor-  and May Be Blocked by Macitentan, a Dual Endothelin-1 Receptor Antagonist

(2015) P. Cipriani et al.   JOURNAL OF RHEUMATOLOGY

A disintegrin and metalloprotease-10 is correlated with disease activity and mediates monocyte migration and adhesion in rheumatoid arthritis

(2015) Takeo Isozaki et al.   Translational Research

Targeting macrophage Histone deacetylase 3 stabilizes atherosclerotic lesions

(2014) M. A. Hoeksema et al.   EMBO Molecular Medicine

Unspliced X-box-binding Protein 1 (XBP1) Protects Endothelial Cells from Oxidative Stress through Interaction with Histone Deacetylase 3

(2014) Daniel Martin et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Histone Deacetylase 3 Unconventional Splicing Mediates Endothelial-to-mesenchymal Transition through Transforming Growth Factor β2

(2013) Lingfang Zeng et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Epithelial-to-Mesenchymal and Endothelial-to-Mesenchymal Transition

(2012) Jason C. Kovacic et al.   CIRCULATION

Role of histone deacetylases in transcription factor regulation and cell cycle modulation in endothelial cells in response to disturbed flow

(2012) D.-Y. Lee et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Role of Endothelial-Mesenchymal Transition (EndoMT) in the Pathogenesis of Fibrotic Disorders

(2011) Sonsoles Piera-Velazquez et al.   AMERICAN JOURNAL OF PATHOLOGY

Galectin-9 Protein Expression in Endothelial Cells Is Positively Regulated by Histone Deacetylase 3

(2011) Saydul Alam et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Targeting HDACs: A Promising Therapy for Alzheimer's Disease

(2011) Ke Xu et al.   Oxidative Medicine and Cellular Longevity

Trichostatin A prevents neointimal hyperplasia via activation of Krüppel like factor 4

(2011) Hae Jin Kee et al.   VASCULAR PHARMACOLOGY

Flow Shear Stress and Atherosclerosis: A Matter of Site Specificity

(2010) Patrizia Nigro et al.   ANTIOXIDANTS & REDOX SIGNALING

Myeloid Type I Interferon Signaling Promotes Atherosclerosis by Stimulating Macrophage Recruitment to Lesions

(2010) Pieter Goossens et al.   Cell Metabolism

Histone Deacetylase 3 Is Critical in Endothelial Survival and Atherosclerosis Development in Response to Disturbed Flow

(2009) Anna Zampetaki et al.   CIRCULATION

The role of endothelial-to-mesenchymal transition in cancer progression

(2008) S Potenta et al.   BRITISH JOURNAL OF CANCER

Deletion of Histone Deacetylase 3 Reveals Critical Roles in S Phase Progression and DNA Damage Control

(2008) Srividya Bhaskara et al.   MOLECULAR CELL