Optimization of Long-Term Human iPSC-Derived Spinal Motor Neuron Culture Using a Dendritic Polyglycerol Amine-Based Substrate

Characterization of Human iPSC-derived Spinal Motor Neurons by Single-cell RNA Sequencing

(2020) Louise Thiry et al.   NEUROSCIENCE

Role of Human‐Induced Pluripotent Stem Cell‐Derived Spinal Cord Astrocytes in the Functional Maturation of Motor Neurons in a Multielectrode Array System

(2019) Arens Taga et al.   Stem Cells Translational Medicine

New substrates for stem cell control

(2018) Sara Schmidt et al.   PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

Intron retention and nuclear loss of SFPQ are molecular hallmarks of ALS

(2018) Raphaelle Luisier et al.   Nature Communications

Nuclear factor-kappaB regulates multiple steps of gliogenesis in the developing murine cerebral cortex

(2018) Laurent Methot et al.   GLIA

ALS disrupts spinal motor neuron maturation and aging pathways within gene co-expression networks

(2016) Ritchie Ho et al.   NATURE NEUROSCIENCE

4-Aminopyridine Induced Activity Rescues Hypoexcitable Motor Neurons from Amyotrophic Lateral Sclerosis Patient-Derived Induced Pluripotent Stem Cells

(2016) Maximilian Naujock et al.   STEM CELLS

Sustained synchronized neuronal network activity in a human astrocyte co-culture system

(2016) Jacobine Kuijlaars et al.   Scientific Reports

Adaptable Hydrogel Networks with Reversible Linkages for Tissue Engineering

(2015) Huiyuan Wang et al.   ADVANCED MATERIALS

Directly Reprogrammed Human Neurons Retain Aging-Associated Transcriptomic Signatures and Reveal Age-Related Nucleocytoplasmic Defects

(2015) Jerome Mertens et al.   Cell Stem Cell

Bax Regulates Neuronal Ca2+ Homeostasis

(2015) B. D'Orsi et al.   JOURNAL OF NEUROSCIENCE

The C9orf72 repeat expansion disrupts nucleocytoplasmic transport

(2015) Ke Zhang et al.   NATURE

Computational and analytical challenges in single-cell transcriptomics

(2015) Oliver Stegle et al.   NATURE REVIEWS GENETICS

Human iPSC-derived motoneurons harbouring TARDBP or C9ORF72 ALS mutations are dysfunctional despite maintaining viability

(2015) Anna-Claire Devlin et al.   Nature Communications

Generation and expansion of highly pure motor neuron progenitors from human pluripotent stem cells

(2015) Zhong-Wei Du et al.   Nature Communications

Systematic adjustment of charge densities and size of polyglycerol amines reduces cytotoxic effects and enhances cellular uptake

(2015) Markus Hellmund et al.   Biomaterials Science

Modeling ALS with iPSCs Reveals that Mutant SOD1 Misregulates Neurofilament Balance in Motor Neurons

(2014) Hong Chen et al.   Cell Stem Cell

Pathways Disrupted in Human ALS Motor Neurons Identified through Genetic Correction of Mutant SOD1

(2014) Evangelos Kiskinis et al.   Cell Stem Cell

Functionalized Polyglycerol Amine Nanogels as Nanocarriers for DNA

(2014) Markus Hellmund et al.   MACROMOLECULAR BIOSCIENCE

Modeling motor neuron disease: the matter of time

(2014) Mandana Arbab et al.   TRENDS IN NEUROSCIENCES

High-efficiency motor neuron differentiation from human pluripotent stem cells and the function of Islet-1

(2014) Qiuhao Qu et al.   Nature Communications

Intrinsic Membrane Hyperexcitability of Amyotrophic Lateral Sclerosis Patient-Derived Motor Neurons

(2014) Brian J. Wainger et al.   Cell Reports

Human iPSC-Based Modeling of Late-Onset Disease via Progerin-Induced Aging

(2013) Justine D. Miller et al.   Cell Stem Cell

Designing degradable hydrogels for orthogonal control of cell microenvironments

(2013) Prathamesh M. Kharkar et al.   CHEMICAL SOCIETY REVIEWS

Accelerated High-Yield Generation of Limb-Innervating Motor Neurons from Human Stem Cells

(2013) M. W. Amoroso et al.   JOURNAL OF NEUROSCIENCE

Targeting RNA Foci in iPSC-Derived Motor Neurons from ALS Patients with a C9ORF72 Repeat Expansion

(2013) D. Sareen et al.   Science Translational Medicine

Investigating the utility of human embryonic stem cell-derived neurons to model ageing and neurodegenerative disease using whole-genome gene expression and splicing analysis

(2012) Rickie Patani et al.   JOURNAL OF NEUROCHEMISTRY

Drug Screening for ALS Using Patient-Specific Induced Pluripotent Stem Cells

(2012) N. Egawa et al.   Science Translational Medicine

Motor Neuron Diversity in Development and Disease

(2010) Kevin C. Kanning et al.   Annual Review of Neuroscience

Retrograde influence of muscle fibers on their innervation revealed by a novel marker for slow motoneurons

(2010) J. V. Chakkalakal et al.   DEVELOPMENT

Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources

(2009) Da Wei Huang et al.   Nature Protocols

Motor Neurons with Axial Muscle Projections Specified by Wnt4/5 Signaling

(2009) Dritan Agalliu et al.   NEURON

Hox Repertoires for Motor Neuron Diversity and Connectivity Gated by a Single Accessory Factor, FoxP1

(2008) Jeremy S. Dasen et al.   CELL

Induced pluripotent stem cells from a spinal muscular atrophy patient

(2008) Allison D. Ebert et al.   NATURE