期刊
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
卷 61, 期 7, 页码 -出版社
WILEY-V C H VERLAG GMBH
DOI: 10.1002/anie.202114513
关键词
Acylboron Compounds; Amino Acids; Carboxylic Acids; Copper; Synthetic Methods
资金
- ETH Zurich
- U.S. Department of Energy (DOE), Office of Science, Office of Basic Energy Sciences (BES) [DE-SC0021055]
- Scholarship Fund of the Swiss Chemical Industry (SSCI)
- U.S. Department of Energy (DOE) [DE-SC0021055] Funding Source: U.S. Department of Energy (DOE)
This method enables the easy preparation of various types of KATs and is compatible with a variety of functional groups, such as alkenes, esters, halides, nitriles, etc.
We report the preparation of potassium acyltrifluoroborates (KATs) from widely available carboxylic acids. Mixed anhydrides of carboxylic acids were prepared using isobutyl chloroformate and transformed to the corresponding KATs using a commercial copper catalyst, B-2(pin)(2), and aqueous KHF2. This method allows for the facile preparation of aliphatic, aromatic, and amino acid-derived KATs and is compatible with a variety of functional groups including alkenes, esters, halides, nitriles, and protected amines.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据