Portability of 245 polygenic scores when derived from the UK Biobank and applied to 9 ancestry groups from the same cohort

Genetics of 35 blood and urine biomarkers in the UK Biobank

(2021) Nasa Sinnott-Armstrong et al.   NATURE GENETICS

Personalized genealogical history of UK individuals inferred from biobank-scale IBD segments

(2021) Ardalan Naseri et al.   BMC BIOLOGY

The Polygenic Score Catalog as an open database for reproducibility and systematic evaluation

(2021) Samuel A. Lambert et al.   NATURE GENETICS

Leveraging both individual-level genetic data and GWAS summary statistics increases polygenic prediction

(2021) Clara Albiñana et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Improved genetic prediction of complex traits from individual-level data or summary statistics

(2021) Qianqian Zhang et al.   Nature Communications

Fast and robust ancestry prediction using principal component analysis

(2020) Daiwei Zhang et al.   BIOINFORMATICS

Efficient toolkit implementing best practices for principal component analysis of population genetic data

(2020) Florian Privé et al.   BIOINFORMATICS

Exploring and visualizing large-scale genetic associations by using PheWeb

(2020) Sarah A. Gagliano Taliun et al.   NATURE GENETICS

Tutorial: a guide to performing polygenic risk score analyses

(2020) Shing Wan Choi et al.   Nature Protocols

Theoretical and empirical quantification of the accuracy of polygenic scores in ancestry divergent populations

(2020) Ying Wang et al.   Nature Communications

Cancer PRSweb: An Online Repository with Polygenic Risk Scores for Major Cancer Traits and Their Evaluation in Two Independent Biobanks

(2020) Lars G. Fritsche et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Polygenic Scores for Height in Admixed Populations

(2020) Bárbara D. Bitarello et al.   G3-Genes Genomes Genetics

A fast and scalable framework for large-scale and ultrahigh-dimensional sparse regression with application to the UK Biobank

(2020) Junyang Qian et al.   PLoS Genetics

LDpred2: better, faster, stronger

(2020) Florian Privé et al.   BIOINFORMATICS

Apparent latent structure within the UK Biobank sample has implications for epidemiological analysis

(2019) Simon Haworth et al.   Nature Communications

Clinical use of current polygenic risk scores may exacerbate health disparities

(2019) Alicia R. Martin et al.   NATURE GENETICS

Efficient Implementation of Penalized Regression for Genetic Risk Prediction

(2019) Florian Privé et al.   GENETICS

A Likelihood-Free Estimator of Population Structure Bridging Admixture Models and Principal Components Analysis

(2019) Irineo Cabreros et al.   GENETICS

Polygenic adaptation on height is overestimated due to uncorrected stratification in genome-wide association studies

(2019) Mashaal Sohail et al.   eLife

Reduced signal for polygenic adaptation of height in UK Biobank

(2019) Jeremy J Berg et al.   eLife

Genetic analyses of diverse populations improves discovery for complex traits

(2019) Genevieve L. Wojcik et al.   NATURE

Analysis of polygenic risk score usage and performance in diverse human populations

(2019) L. Duncan et al.   Nature Communications

GRAF-pop: A Fast Distance-Based Method To Infer Subject Ancestry from Multiple Genotype Datasets Without Principal Components Analysis

(2019) Yumi Jin et al.   G3-Genes Genomes Genetics

Efficient analysis of large-scale genome-wide data with two R packages: bigstatsr and bigsnpr

(2018) Florian Privé et al.   BIOINFORMATICS

Mixed-model association for biobank-scale datasets

(2018) Po-Ru Loh et al.   NATURE GENETICS

Association analyses of more than 140,000 men identify 63 new prostate cancer susceptibility loci

(2018) Fredrick R. Schumacher et al.   NATURE GENETICS

Efficiently controlling for case-control imbalance and sample relatedness in large-scale genetic association studies

(2018) Wei Zhou et al.   NATURE GENETICS

The UK Biobank resource with deep phenotyping and genomic data

(2018) Clare Bycroft et al.   NATURE

Multiethnic polygenic risk scores improve risk prediction in diverse populations

(2017) Carla Márquez-Luna et al.   GENETIC EPIDEMIOLOGY

Association analysis identifies 65 new breast cancer risk loci

(2017) Kyriaki Michailidou et al.   NATURE

Childhood adiposity and risk of type 1 diabetes: A Mendelian randomization study

(2017) J. C. Censin et al.   PLOS MEDICINE

MixFit: Methodology for Computing Ancestry-Related Genetic Scores at the Individual Level and Its Application to the Estonian and Finnish Population Studies

(2017) Toomas Haller et al.   PLoS One

Winner's Curse Correction and Variable Thresholding Improve Performance of Polygenic Risk Modeling Based on Genome-Wide Association Study Summary-Level Data

(2016) Jianxin Shi et al.   PLoS Genetics

Using Genetic Distance to Infer the Accuracy of Genomic Prediction

(2016) Marco Scutari et al.   PLoS Genetics

A comprehensive 1000 Genomes–based genome-wide association meta-analysis of coronary artery disease

(2015) Majid Nikpay et al.   NATURE GENETICS

R PheWAS: data analysis and plotting tools for phenome-wide association studies in the R environment

(2014) Robert J. Carroll et al.   BIOINFORMATICS

Fast and Efficient Estimation of Individual Ancestry Coefficients

(2014) Eric Frichot et al.   GENETICS

fastSTRUCTURE: Variational Inference of Population Structure in Large SNP Data Sets

(2014) Anil Raj et al.   GENETICS

No Evidence from Genome-Wide Data of a Khazar Origin for the Ashkenazi Jews

(2014) Doron M. Behar et al.   HUMAN BIOLOGY

Accurate and Robust Genomic Prediction of Celiac Disease Using Statistical Learning

(2014) Gad Abraham et al.   PLoS Genetics

Improved ancestry inference using weights from external reference panels

(2013) Chia-Yen Chen et al.   BIOINFORMATICS

Reconstructing the Population Genetic History of the Caribbean

(2013) Andrés Moreno-Estrada et al.   PLoS Genetics

Inference of Population Structure using Dense Haplotype Data

(2012) Daniel John Lawson et al.   PLoS Genetics

Predicting genetic predisposition in humans: the promise of whole-genome markers

(2010) Gustavo de los Campos et al.   NATURE REVIEWS GENETICS

Fast model-based estimation of ancestry in unrelated individuals

(2009) D. H. Alexander et al.   GENOME RESEARCH

Bias-reduced estimators and confidence intervals for odds ratios in genome-wide association studies

(2008) H. Zhong et al.   BIOSTATISTICS

Genes mirror geography within Europe

(2008) John Novembre et al.   NATURE