S-nitrosylation of Hsp90 promotes cardiac hypertrophy in mice through GSK3β signaling

Nitric oxide prevents aortic valve calcification by S-nitrosylation of USP9X to activate NOTCH signaling

(2021) Uddalak Majumdar et al.   Science Advances

Protein S-nitrosylation regulates proteostasis and viability of hematopoietic stem cell during regeneration

(2021) Weiwei Yi et al.   Cell Reports

bFGF alleviates diabetes-associated endothelial impairment by downregulating inflammation via S-nitrosylation pathway

(2021) Gen Chen et al.   Redox Biology

S-nitrosylation of c-Jun N-terminal kinase mediates pressure overload-induced cardiac dysfunction and fibrosis

(2021) Miao Zhou et al.   ACTA PHARMACOLOGICA SINICA

Inhibition of HSP90 S‐nitrosylation Alleviates Cardiac Fibrosis via TGFβ/SMAD3 Signaling Pathway

(2021) Xiyue Zhang et al.   BRITISH JOURNAL OF PHARMACOLOGY

HINT1 (Histidine Triad Nucleotide-Binding Protein 1) Attenuates Cardiac Hypertrophy Via Suppressing HOXA5 (Homeobox A5) Expression

(2021) Yan Zhang et al.   CIRCULATION

Hsp90 Inhibitor Attenuates the Development of Pathophysiological Cardiac Fibrosis in Mouse Hypertrophy via Suppression of the Calcineurin-NFAT and c-Raf-Erk Pathways

(2021) Tetsuro Marunouchi et al.   JOURNAL OF CARDIOVASCULAR PHARMACOLOGY

S-Nitrosylation of Muscle LIM Protein Facilitates Myocardial Hypertrophy Through Toll-Like Receptor 3-Mediated Receptor-Interacting ProteinKinase 3 and NLRP3 Inflammasome Activation

(2020) Xin Tang et al.   CIRCULATION

Nitric Oxide-cGMP Signaling in Hypertension

(2020) Ehsan Ataei Ataabadi et al.   HYPERTENSION

The piRNA CHAPIR regulates cardiac hypertrophy by controlling METTL3-dependent N6-methyladenosine methylation of Parp10 mRNA

(2020) Xiang-Qian Gao et al.   NATURE CELL BIOLOGY

Proteasome-Dependent Regulation of Distinct Metabolic States During Long-Term Culture of Human iPSC-Derived Cardiomyocytes

(2019) Antje Ebert et al.   CIRCULATION RESEARCH

Hsp90 middle domain phosphorylation initiates a complex conformational program to recruit the ATPase-stimulating cochaperone Aha1

(2019) Wanping Xu et al.   Nature Communications

S-Nitrosylation of Plastin-3 Exacerbates Thoracic Aortic Dissection Formation via Endothelial Barrier Dysfunction

(2019) Lihong Pan et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Mitochondrial HSP90 Accumulation Promotes Vascular Remodeling in Pulmonary Arterial Hypertension

(2018) Olivier Boucherat et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

eNOS S-nitrosylation mediated OxLDL-induced endothelial dysfunction via increasing the interaction of eNOS with β‑catenin

(2018) Wan Wang et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Hydrogen sulfide attenuates oxidative stress-induced NLRP3 inflammasome activation via S-sulfhydrating c-Jun at Cys269 in macrophages

(2018) Zhe Lin et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

ProteinS-Nitrosylation Controls Glycogen Synthase Kinase 3β Function Independent of Its Phosphorylation StateNovelty and Significance

(2018) Sheng-Bing Wang et al.   CIRCULATION RESEARCH

Nitric oxide signalling in cardiovascular health and disease

(2018) Charlotte Farah et al.   Nature Reviews Cardiology

Mechanisms of physiological and pathological cardiac hypertrophy

(2018) Michinari Nakamura et al.   Nature Reviews Cardiology

Hsp90 and Hsp70 chaperones: Collaborators in protein remodeling

(2018) Olivier Genest et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Heat-shock protein 90 modulates cardiac ventricular hypertrophy via activation of MAPK pathway

(2018) Shoko Tamura et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

HSP90 promotes cell glycolysis, proliferation and inhibits apoptosis by regulating PKM2 abundance via Thr-328 phosphorylation in hepatocellular carcinoma

(2017) Qiuran Xu et al.   Molecular Cancer

The HSP90 chaperone machinery

(2017) Florian H. Schopf et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

S-Nitrosylation in neurogenesis and neuronal development

(2015) Shu-ichi Okamoto et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

S-Nitrosylation of Calcium-Handling Proteins in Cardiac Adrenergic Signaling and HypertrophyNovelty and Significance

(2015) Tomoya Irie et al.   CIRCULATION RESEARCH

Heat-shock-protein 90 protects from downregulation of HIF-1α in calcineurin-induced myocardial hypertrophy

(2015) Sabine Eschricht et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Post-translational modifications of Hsp90 and their contributions to chaperone regulation

(2011) Mehdi Mollapour et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Cardiac-specific mindin overexpression attenuates cardiac hypertrophy via blocking AKT/GSK3β and TGF-β1–Smad signalling

(2011) Ling Yan et al.   CARDIOVASCULAR RESEARCH

S -Nitrosylation in Cardiovascular Signaling

(2010) Brian Lima et al.   CIRCULATION RESEARCH

Hsp 70/Hsp 90 organizing protein as a nitrosylation target in cystic fibrosis therapy

(2010) N. V. Marozkina et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Hsp90 transcriptionally and post-translationally regulates the expression of NDRG1 and maintains the stability of its modifying kinase GSK3β

(2009) Vanessa M. Banz et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Protein denitrosylation: enzymatic mechanisms and cellular functions

(2009) Moran Benhar et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY