Immunisation with UB-312 in the Thy1SNCA mouse prevents motor performance deficits and oligomeric α-synuclein accumulation in the brain and gut
出版年份 2021 全文链接
标题
Immunisation with UB-312 in the Thy1SNCA mouse prevents motor performance deficits and oligomeric α-synuclein accumulation in the brain and gut
作者
关键词
-
出版物
ACTA NEUROPATHOLOGICA
Volume 143, Issue 1, Pages 55-73
出版商
Springer Science and Business Media LLC
发表日期
2021-11-06
DOI
10.1007/s00401-021-02381-5
参考文献
相关参考文献
注意：仅列出部分参考文献，下载原文获取全部文献信息。- Donanemab in Early Alzheimer’s Disease
- (2021) Mark A. Mintun et al. NEW ENGLAND JOURNAL OF MEDICINE
- Amyloid-β and α-Synuclein Immunotherapy: From Experimental Studies to Clinical Trials
- (2021) Jacqui Taryn Nimmo et al. Frontiers in Neuroscience
- Alpha-Synuclein Physiology and Pathology: A Perspective on Cellular Structures and Organelles
- (2020) Luis D. Bernal-Conde et al. Frontiers in Neuroscience
- Microglia clear neuron-released α-synuclein via selective autophagy and prevent neurodegeneration
- (2020) Insup Choi et al. Nature Communications
- Neuroinflammation in dementia with Lewy bodies: a human post-mortem study
- (2020) Jay Amin et al. Translational Psychiatry
- Squalamine Restores the Function of the Enteric Nervous System in Mouse Models of Parkinson’s Disease
- (2020) Christine L. West et al. Journal of Parkinsons Disease
- Novel antibodies detect additional α-synuclein pathology in synucleinopathies: potential development for immunotherapy
- (2020) Jacqui T. Nimmo et al. Alzheimers Research & Therapy
- Dementia with Lewy bodies: an update and outlook
- (2019) Tiago Fleming Outeiro et al. Molecular Neurodegeneration
- Prevalence and duration of non-motor symptoms in prodromal Parkinson's disease
- (2019) R. Durcan et al. EUROPEAN JOURNAL OF NEUROLOGY
- α-Synuclein and astrocytes: tracing the pathways from homeostasis to neurodegeneration in Lewy body disease
- (2019) Zachary A. Sorrentino et al. ACTA NEUROPATHOLOGICA
- Cellular models of alpha‐synuclein toxicity and aggregation
- (2019) Marion Delenclos et al. JOURNAL OF NEUROCHEMISTRY
- Gastrointestinal nervous system α-synuclein as a potential biomarker of Parkinson disease
- (2018) Fudong Yan et al. MEDICINE
- Parkinson disease with constipation: clinical features and relevant factors
- (2018) Qiu-Jin Yu et al. Scientific Reports
- Frequency of non-motor symptoms in Parkinson’s disease presenting to tertiary care centre in Pakistan: an observational, cross-sectional study
- (2018) Shahid Mukhtar et al. BMJ Open
- Microglia Response During Parkinson’s Disease: Alpha-Synuclein Intervention
- (2018) Sara A. Ferreira et al. Frontiers in Cellular Neuroscience
- Chronic stress-induced gut dysfunction exacerbates Parkinson's disease phenotype and pathology in a rotenone-induced mouse model of Parkinson's disease
- (2018) Hemraj B. Dodiya et al. NEUROBIOLOGY OF DISEASE
- Changes in the cell population in brain white matter in multiple system atrophy
- (2017) Charlotte Havelund Nykjaer et al. MOVEMENT DISORDERS
- Local Cues Establish and Maintain Region-Specific Phenotypes of Basal Ganglia Microglia
- (2017) Lindsay M. De Biase et al. NEURON
- Pathological α-synuclein in gastrointestinal tissues from prodromal Parkinson disease patients
- (2016) Morten Gersel Stokholm et al. ANNALS OF NEUROLOGY
- Advances in markers of prodromal Parkinson disease
- (2016) Ronald B. Postuma et al. Nature Reviews Neurology
- Structural and functional properties of prefibrillar α-synuclein oligomers
- (2016) Laura Pieri et al. Scientific Reports
- Neocortical Neuronal Loss in Patients with Multiple System Atrophy: A Stereological Study
- (2015) Lisette Salvesen et al. CEREBRAL CORTEX
- Prediagnostic presentations of Parkinson's disease in primary care: a case-control study
- (2015) Anette Schrag et al. LANCET NEUROLOGY
- Gastrointestinal dysfunction in Parkinson's disease
- (2015) Alfonso Fasano et al. LANCET NEUROLOGY
- Low levels of astroglial markers in Parkinson’s disease: relationship to α-synuclein accumulation
- (2015) Junchao Tong et al. NEUROBIOLOGY OF DISEASE
- α-Synuclein, a chemoattractant, directs microglial migration via H2O2-dependent Lyn phosphorylation
- (2015) Shijun Wang et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Next-generation active immunization approach for synucleinopathies: implications for Parkinson’s disease clinical trials
- (2014) Markus Mandler et al. ACTA NEUROPATHOLOGICA
- Heterogeneity and phenotypic plasticity of glial cells in the mammalian enteric nervous system
- (2014) Werend Boesmans et al. GLIA
- Enteric GFAP expression and phosphorylation in Parkinson's disease
- (2014) Thomas Clairembault et al. JOURNAL OF NEUROCHEMISTRY
- Accumulation of α-synuclein in the bowel of patients in the pre-clinical phase of Parkinson’s disease
- (2013) David Hilton et al. ACTA NEUROPATHOLOGICA
- Meta-analysis of early nonmotor features and risk factors for Parkinson disease
- (2012) Alastair J. Noyce et al. ANNALS OF NEUROLOGY
- Differential distribution and activation of microglia in the brain of male C57BL/6J mice
- (2012) Ting-Ting Yang et al. Brain Structure & Function
- Antibody-Aided Clearance of Extracellular -Synuclein Prevents Cell-to-Cell Aggregate Transmission
- (2012) E.-J. Bae et al. JOURNAL OF NEUROSCIENCE
- Exosomal cell-to-cell transmission of alpha synuclein oligomers
- (2012) Karin M Danzer et al. Molecular Neurodegeneration
- Colonic inflammation in Parkinson's disease
- (2012) David Devos et al. NEUROBIOLOGY OF DISEASE
- Mice overexpressing wild-type human alpha-synuclein display alterations in colonic myenteric ganglia and defecation
- (2012) L. Wang et al. NEUROGASTROENTEROLOGY AND MOTILITY
- A Progressive Mouse Model of Parkinson’s Disease: The Thy1-aSyn (“Line 61”) Mice
- (2012) Marie-Francoise Chesselet et al. Neurotherapeutics
- Exogenous α-Synuclein Fibrils Induce Lewy Body Pathology Leading to Synaptic Dysfunction and Neuron Death
- (2011) Laura A. Volpicelli-Daley et al. NEURON
- Assessment of α-Synuclein Secretion in Mouse and Human Brain Parenchyma
- (2011) Evangelia Emmanouilidou et al. PLoS One
- Direct Transfer of α-Synuclein from Neuron to Astroglia Causes Inflammatory Responses in Synucleinopathies
- (2010) He-Jin Lee et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Parkinson's at risk syndrome: Can Parkinson's disease be predicted?
- (2010) Matthew B. Stern et al. MOVEMENT DISORDERS
- Degeneration in Different Parkinsonian Syndromes Relates to Astrocyte Type and Astrocyte Protein Expression
- (2009) Yun Ju C. Song et al. JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY
- Allergy and the gastrointestinal system
- (2008) G. Vighi et al. CLINICAL AND EXPERIMENTAL IMMUNOLOGY
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExploreAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started