PPAR-α Agonist GW7647 Protects Against Oxidative Stress and Iron Deposit via GPx4 in a Transgenic Mouse Model of Alzheimer’s Diseases

Lipid peroxidation and ferroptosis: The role of GSH and GPx4

(2020) Fulvio Ursini et al.   FREE RADICAL BIOLOGY AND MEDICINE

The Novel Role of PPAR Alpha in the Brain: Promising Target in Therapy of Alzheimer’s Disease and Other Neurodegenerative Disorders

(2020) Sylwia Wójtowicz et al.   NEUROCHEMICAL RESEARCH

Free radicals in Alzheimer's disease: Lipid peroxidation biomarkers

(2019) Carmen Peña-Bautista et al.   CLINICA CHIMICA ACTA

Alzheimer Disease: An Update on Pathobiology and Treatment Strategies

(2019) Justin M. Long et al.   CELL

Identifying qualitative differences in PPARα signaling networks in human and rat hepatocytes and their significance for next generation chemical risk assessment methods

(2019) Patrick D. McMullen et al.   TOXICOLOGY IN VITRO

Peroxisome Proliferator-Activated Receptor Gamma Coactivator-1 Alpha as a Novel Target for Bipolar Disorder and Other Neuropsychiatric Disorders

(2018) Andrew A. Nierenberg et al.   BIOLOGICAL PSYCHIATRY

Metal Ion Effects on Aβ and Tau Aggregation

(2018) Anne Kim et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Targeting Neuroinflammation as a Therapeutic Strategy for Alzheimer’s Disease: Mechanisms, Drug Candidates, and New Opportunities

(2018) Wing-Yu Fu et al.   ACS Chemical Neuroscience

Iron and Alzheimer’s Disease: From Pathogenesis to Therapeutic Implications

(2018) Jun-Lin Liu et al.   Frontiers in Neuroscience

Localization of PPAR isotypes in the adult mouse and human brain

(2016) Anna Warden et al.   Scientific Reports

Preferential PPAR-α activation reduces neuroinflammation, and blocks neurodegenerationin vivo

(2015) Mohammad A. Esmaeili et al.   HUMAN MOLECULAR GENETICS

Glutaminolysis and Transferrin Regulate Ferroptosis

(2015) Minghui Gao et al.   MOLECULAR CELL

The effect of iron in MRI and transverse relaxation of amyloid-beta plaques in Alzheimer's disease

(2014) Mark D. Meadowcroft et al.   NMR IN BIOMEDICINE

Neuroprotective Potential of Peroxisome Proliferator Activated Receptor-αAgonist in Cognitive Impairment in Parkinson’s Disease: Behavioral, Biochemical, and PBPK Profile

(2014) Dedeepya Uppalapati et al.   PPAR Research

The PPARγ agonist pioglitazone crosses the blood–brain barrier and reduces tumor growth in a human xenograft model

(2013) Christian Grommes et al.   CANCER CHEMOTHERAPY AND PHARMACOLOGY

Metabolic Stress Modulates Alzheimer’s β-Secretase Gene Transcription via SIRT1-PPARγ-PGC-1 in Neurons

(2013) Ruishan Wang et al.   Cell Metabolism

Regulation of Cyclic AMP Response Element Binding and Hippocampal Plasticity-Related Genes by Peroxisome Proliferator-Activated Receptor α

(2013) Avik Roy et al.   Cell Reports

Aβ1-42-mediated down-regulation of Uch-L1 is dependent on NF-κB activation and impaired BACE1 lysosomal degradation

(2012) Michela Guglielmotto et al.   AGING CELL

Ferroptosis: An Iron-Dependent Form of Nonapoptotic Cell Death

(2012) Scott J. Dixon et al.   CELL

Peroxisome Proliferator-Activated Receptor-α Activation Promotes Macrophage Reverse Cholesterol Transport Through a Liver X Receptor–Dependent Pathway

(2011) Kazuhiro Nakaya et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY