Rational Approach to Identify RNA Targets of Natural Products Enables Identification of Nocathiacin as an Inhibitor of an Oncogenic RNA

Discovery of Surfactins as Inhibitors of MicroRNA Processing Using Cat-ELCCA

(2021) Andrew W. Robertson et al.   ACS Medicinal Chemistry Letters

Natural Products as Sources of New Drugs over the Nearly Four Decades from 01/1981 to 09/2019

(2020) David J. Newman et al.   JOURNAL OF NATURAL PRODUCTS

Continuous bioactivity-dependent evolution of an antibiotic biosynthetic pathway

(2020) Chad W. Johnston et al.   Nature Communications

Natural Products with Potential to Treat RNA Virus Pathogens Including SARS-CoV-2

(2020) Mitchell P. Christy et al.   JOURNAL OF NATURAL PRODUCTS

Perspectives on targeting RNA with small molecules to capture opportunities at the intersection of chemistry, biology, and medicine

(2019) Matthew D. Disney   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

RNA-ALIS: Methodology for screening soluble RNAs as small molecule targets using ALIS affinity-selection mass spectrometry

(2019) Noreen F. Rizvi et al.   METHODS

Leveraging a large microbial strain collection for natural product discovery

(2019) Andrew D. Steele et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The biochemical basis of microRNA targeting efficacy

(2019) Sean E. McGeary et al.   SCIENCE

Small Molecule Inhibition of microRNA-210 Reprograms an Oncogenic Hypoxic Circuit

(2017) Matthew G. Costales et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

DrugBank 5.0: a major update to the DrugBank database for 2018

(2017) David S Wishart et al.   NUCLEIC ACIDS RESEARCH

Defining RNA–Small Molecule Affinity Landscapes Enables Design of a Small Molecule Inhibitor of an Oncogenic Noncoding RNA

(2017) Sai Pradeep Velagapudi et al.   ACS Central Science

Analysis of secondary structural elements in human microRNA hairpin precursors

(2016) Biao Liu et al.   BMC BIOINFORMATICS

Natural Products as Sources of New Drugs from 1981 to 2014

(2016) David J. Newman et al.   JOURNAL OF NATURAL PRODUCTS

Identification and Validation of Novel Small Molecule Disruptors of HuR-mRNA Interaction

(2015) Xiaoqing Wu et al.   ACS Chemical Biology

Sequence-based design of bioactive small molecules that target precursor microRNAs

(2014) Sai Pradeep Velagapudi et al.   Nature Chemical Biology

MicroRNA-18a is elevated in prostate cancer and promotes tumorigenesis through suppressing STK4 in vitro and in vivo

(2014) T-I Hsu et al.   Oncogenesis

The miR-17/92 cluster: a comprehensive update on its genomics, genetics, functions and increasingly important and numerous roles in health and disease

(2013) E Mogilyansky et al.   CELL DEATH AND DIFFERENTIATION

miRClassify: An advanced web server for miRNA family classification and annotation

(2013) Quan Zou et al.   COMPUTERS IN BIOLOGY AND MEDICINE

Target identification and mechanism of action in chemical biology and drug discovery

(2013) Monica Schenone et al.   Nature Chemical Biology

Chemical Biology of Natural Products on the Basis of Identification of Target Proteins

(2012) Minoru Ueda   CHEMISTRY LETTERS

miR-18a Impairs DNA Damage Response through Downregulation of Ataxia Telangiectasia Mutated (ATM) Kinase

(2011) Libing Song et al.   PLoS One

Molecular Determinants of Microbial Resistance to Thiopeptide Antibiotics

(2010) Sascha Baumann et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Discovering ligands for a microRNA precursor with peptoid microarrays

(2009) Sara Chirayil et al.   NUCLEIC ACIDS RESEARCH