Article
Public, Environmental & Occupational Health
Mandy Goldberg, Mary Diaz-Santana, Katie M. O'Brien, Shanshan Zhao, Clarice R. Weinberg, Dale P. Sandler
Summary: This study examined the association between gestational hypertensive disorders and breast cancer in a cohort of women with a family history of breast cancer. The results showed that a history of gestational hypertensive disorder was not associated with breast cancer risk.
Article
Endocrinology & Metabolism
Xiujuan Su, Yang Liu, Guohua Li, Xiaosong Liu, Shijia Huang, Tao Duan, Qiaoling Du
Summary: This study found that hypothyroxinemia during pregnancy was associated with an increased risk of preeclampsia-eclampsia, especially in women with persistent hypothyroxinemia in early pregnancy. However, there was no significant association between hypothyroxinemia and gestational hypertension.
FRONTIERS IN ENDOCRINOLOGY
(2021)
Review
Nutrition & Dietetics
Dorina Greff, Szilard Vancsa, Alex Varadi, Julia Szinte, Sunjune Park, Peter Hegyi, Peter Nyirady, Nandor Acs, Eszter Maria Horvath, Szabolcs Varbiro
Summary: Inositol supplementation has a positive effect on preventing gestational diabetes, reducing the incidence of GDM and glucose levels, as well as decreasing the risk of insulin need and maternal complications.
Article
Health Care Sciences & Services
Marija Majda Perisic, Klemo Vladimir, Sarah Karpov, Mario Storga, Ali Mostashari, Raya Khanin
Summary: Preeclampsia and gestational hypertensive disorders are common complications of pregnancy with long-term consequences. This study developed a risk score using machine learning to screen for GHD early. It confirmed that high BMI is a risk factor for GHD and explored the relationship between GHD and genetically constructed anthropometric measures and biomarkers.
JOURNAL OF PERSONALIZED MEDICINE
(2022)
Article
Peripheral Vascular Disease
Joana Lopes Perdigao, Jennifer Lewey, Adi Hirshberg, Nathanael Koelper, Sindhu K. Srinivas, Michal A. Elovitz, Lisa D. Levine
Summary: This study suggests that a short course of postpartum furosemide significantly improves blood pressure control in women with hypertensive disorders of pregnancy, particularly among those without severe disease. The use of furosemide reduced the risk of persistent hypertension at 7 days postpartum and shortened the days to resolution of hypertension, without significant differences in readmissions or need for additional antihypertensive medication between groups.
Review
Biochemistry & Molecular Biology
Ramana Vaka, Evangeline Deer, Babbette LaMarca
Summary: Despite extensive research, the pathogenesis of preeclampsia (PE) remains unclear and lacks FDA-approved treatments. Mitochondrial oxidative stress has been identified as a crucial factor in PE development and holds potential as a target for therapy.
Article
Obstetrics & Gynecology
Titus K. Beyuo, Emma R. Lawrence, Emily K. Kobernik, Samuel A. Oppong
Summary: This study compared the efficacy of a 12-hour versus 24-hour regimen of intramuscular magnesium sulfate in the treatment of eclampsia and preeclampsia. The results showed that the 12-hour regimen had similar seizure rates as the 24-hour regimen, but with fewer side effects and shorter hospital stay.
INTERNATIONAL JOURNAL OF GYNECOLOGY & OBSTETRICS
(2022)
Article
Biochemistry & Molecular Biology
Andrea Fernandez-Valero, Nerea Pena-Montero, Fuensanta Lima-Rubio, Carolina Gutierrez-Repiso, Teresa Maria Linares-Pineda, Maria Jose Picon-Cesar, Raquel Sancho-Marin, Francisco J. Tinahones, Sonsoles Morcillo, Maria Molina-Vega
Summary: The study aimed to compare the effects of metformin and insulin on oxidative stress and intestinal permeability in women with gestational diabetes mellitus (GDM). The results showed that metformin could prevent an increase in intestinal permeability in GDM patients but failed to prevent an increase in oxidative stress related to hyperglycemia.
Article
Obstetrics & Gynecology
Alisse Hauspurg, Ellen W. Seely, Janet Rich-Edwards, Christina Hayduchok, Samantha Bryan, Andrea T. Roche, Arun Jeyabalan, Esa M. Davis, Renee Hart, Jada Shirriel, Janet Catov
Summary: This study aimed to test the feasibility of a randomised trial of home blood pressure monitoring paired with a remote lifestyle intervention in individuals with a hypertensive disorder of pregnancy in the first year postpartum. The study found that the combination of home blood pressure monitoring and lifestyle intervention was feasible in the first year postpartum, but the rate of hypertension remained high.
BJOG-AN INTERNATIONAL JOURNAL OF OBSTETRICS AND GYNAECOLOGY
(2023)
Article
Biochemistry & Molecular Biology
Iwona Olszewska-Czyz, Kristina Kralik, Marin Tota, Jelena Prpic
Summary: Periodontitis is a common oral disease caused by bacteria and immune responses. This study shows that the addition of hyaluronic acid to non-surgical periodontal therapy can increase antioxidants in saliva and improve the prognosis and results of periodontal therapy. Additionally, the levels of gingival inflammation and periodontal destruction are closely related to these markers.
Article
Clinical Neurology
Moinay Kim, Joonho Byun, Yeongu Chung, Si Un Lee, Ji Eun Park, Wonhyoung Park, Jung Cheol Park, Jae Sung Ahn, Seungjoo Lee
Summary: Administering ROS scavengers to patients with acute ICH significantly reduced PHE volume, shortened time to reach target Richmond Agitation Sedation Scale, and reduced length of stay in the intensive care unit.
Article
Biochemistry & Molecular Biology
Branislav Kura, Maria Szantova, Tyler W. LeBaron, Viliam Mojto, Miroslav Barancik, Barbara Szeiffova Bacova, Barbora Kalocayova, Matus Sykora, Ludmila Okruhlicova, Narcisa Tribulova, Anna Gvozdjakova, Zuzana Sumbalova, Jarmila Kucharska, Xenia Faktorova, Martina Jakabovicova, Zuzana Durkovicova, Jan Macutek, Michaela Koscova, Jan Slezak
Summary: This study suggests that molecular hydrogen has positive effects on non-alcoholic fatty liver disease, including lowering weight and body mass index. Moreover, hydrogen-rich water has no significant impact on liver function and can improve lipid profile and lactate dehydrogenase levels. The mild increase of certain biomarkers may indicate the hormetic effects of molecular hydrogen. Further research is needed to explore its preventive and therapeutic potential.
Article
Chemistry, Medicinal
Vahideh Behrouz, Golbon Sohrab, Mehdi Hedayati, Meghdad Sedaghat
Summary: This study shows that daily administration of 30 mg crocin supplement to patients with type 2 diabetes mellitus reduces the concentrations of hs-CRP, TNF-alpha, and NF-kappa B which are involved in the pathogenesis of complications of T2DM.
PHYTOTHERAPY RESEARCH
(2021)
Article
Cell Biology
Sandra M. Blois, Paula D. Prince, Sophia Borowski, Monica Galleano, Gabriela Barrientos
Summary: Utilizing the SHRSP model, this study investigated placental mechanisms promoting superimposed preeclampsia in women with chronic hypertension. The findings revealed sustained activation of cellular stress response in SHRSP placentas, leading to redox imbalance and significant alterations in placental glycocode. The study highlights the potential role of glycoredox balance as a promising target for interventions in hypertensive disorders of pregnancy.
Article
Endocrinology & Metabolism
Panisa Hantrakun, Rattanaporn Sekararithi, Thidarat Jaiwongkam, Sirinart Kumfu, Chatree Chai-adisaksopha, Nipon Chattipakorn, Theera Tongsong, Phudit Jatavan
Summary: Metformin does not improve or worsen oxidative stress and platelet dysfunction in women with gestational diabetes mellitus, but can significantly reduce fetal weight, theoretically preventing macrosomia.
ENDOCRINE CONNECTIONS
(2022)
Article
Pediatrics
Rene O. Perez-Ramirez, Juan Carlos Lona-Reyes, Cesar A. Ochoa-Meza, Larissa M. Gomez-Ruiz, Ruth Y. Ramos-Gutierrez, E. Elizabeth Camarena-Pulido, J. Antonio Gallegos-Marin
ANALES DE PEDIATRIA
(2019)
Article
Food Science & Technology
Patricia Quezada-Fernandez, Jhonatan Trujillo-Quiros, Sara Pascoe-Gonzalez, Walter A. Trujillo-Rangel, David Cardona-Mueller, Carlos G. Ramos-Becerra, Maricruz Barocio-Pantoja, Mariana Rodriguez-de la Cerda, Esther Nerida Sanchez-Rodriguez, Ernesto G. Cardona-Munoz, Leonel Garcia-Benavides, Fernando Grover-Paez
INTERNATIONAL JOURNAL OF FOOD SCIENCES AND NUTRITION
(2019)
Article
Cell Biology
Simon Quetzalcoatl Rodriguez-Lara, Walter Angel Trujillo-Rangel, Araceli Castillo-Romero, Sylvia Elena Totsuka-Sutto, Teresa Arcelia Garcia-Cobian, Ernesto German Cardona-Munoz, Alejandra Guillermina Miranda-Diaz, Ernesto Javier Ramirez-Lizardo, Leonel Garcia-Benavides
OXIDATIVE MEDICINE AND CELLULAR LONGEVITY
(2019)
Article
Endocrinology & Metabolism
Betsabe Contreras-Haro, Sandra Ofelia Hernandez-Gonzalez, Laura Gonzalez-Lopez, Maria Claudia Espinel-Bermudez, Leonel Garcia-Benavides, Edsaul Perez-Guerrero, Maria Luisa Vazquez-Villegas, Jose Antonio Robles-Cervantes, Mario Salazar-Paramo, Diana Mercedes Hernandez-Corona, Arnulfo Hernan Nava-Zavala, Jorge I. Gamez-Nava
DIABETOLOGY & METABOLIC SYNDROME
(2019)
Article
Multidisciplinary Sciences
Adriana Diaz-Rivera, Alejandra Meza-Rios, Victoria Chagoya de Sanchez, Gabriela Velasco-Loyden, Leonel Garcia-Benavides, Luis F. Jave-Suarez, Hugo Christian Monroy-Ramirez, Arturo Santos-Garcia, Juan Armendariz-Borunda, Ana Sandoval-Rodriguez
Article
Chemistry, Medicinal
Sara Pascoe-Gonzalez, Maria Guadalupe Ramos-Zavala, Miguel Angel Buenrostro Ahued, Sandra Ofelia Hernandez-Gonzalez, Ernesto German Cardona-Munoz, Leonel Garcia-Benavides, Fernando Grover-Paez
Summary: This study shows that the herbarium mixture (G. ulmifolia/T. stans) improved the glycemic profile in patients with T2DM.
JOURNAL OF MEDICINAL FOOD
(2021)
Article
Multidisciplinary Sciences
Homero Contreras-Salinas, Alejandra Meza-Rios, Jesus Garcia-Banuelos, Ana Sandoval-Rodriguez, Laura Sanchez-Orozco, Leonel Garcia-Benavides, Ricardo De la Rosa-Bibiano, Hugo Christian Monroy Ramirez, Jorge Gutierrez-Cuevas, Arturo Santos-Garcia, Juan Armendariz-Borunda
Article
Endocrinology & Metabolism
Jorge Barrera-Alcocer, Leonel Garcia-Benavides, Jose F. Munoz-Valle, Ulises de la Cruz-Mosso, Ramon A. Gonzalez, Sonia Luquin, Luz del C. Alarcon-Romero, Linda A. Marino-Ortega, Ines Matia-Garcia, Isela Parra-Rojas
Summary: The study identified the presence of HAd36 DNA in adipose tissue of women undergoing weight reduction surgery in 31% of the samples, however, it was not significantly associated with changes in adipocyte morphology, or the expression of C/EBP beta and HIF-1 alpha. Further research is needed to confirm these findings.
DIABETES METABOLIC SYNDROME AND OBESITY-TARGETS AND THERAPY
(2021)
Article
Biotechnology & Applied Microbiology
M. Pena-Rodriguez, N. Vega-Magana, Leonel Garcia-Benavides, J. S. Zepeda-Nuno, G. Y. Gutierrez-Silerio, L. A. Gonzalez-Hernandez, J. F. Andrade-Villanueva, S. Del Toro-Arreola, A. L. Pereira-Suarez, M. R. Bueno-Topete
Summary: The study showed that butyrate effectively regulates inflammatory response, tight junction protein expression, and limits bacterial diversity loss in cirrhosis patients. This research suggests that butyrate could be an interesting postbiotic metabolomic intervention for intestinal epithelium dysfunction in liver disease.
JOURNAL OF APPLIED MICROBIOLOGY
(2021)
Review
Cell Biology
Walter Angel Trujillo-Rangel, Leonel Garcia-Valdes, Miriam Mendez-del Villar, Rolando Castaneda-Arellano, Sylvia Elena Totsuka-Sutto, Leonel Garcia-Benavides
Summary: Ischemia-reperfusion (I-R) injury, caused by restoring blood flow to ischemic tissues or organs, involves various signaling pathways and molecular targets. These discoveries are important as they help reduce oxidative stress-induced damage and play a crucial role in resolving I-R.
OXIDATIVE MEDICINE AND CELLULAR LONGEVITY
(2022)
Article
Obstetrics & Gynecology
Eva Elizabet Camarena Pulido, Salvador Mora Gonzalez, America Aime Corona Gutierrez, Mireya Robledo Aceves, Paola Basso Barba, Yunuen Salgado Leyva
Summary: Supplementing with 5,000 IU of vitamin D for eight weeks had no significant effect on the glycemic profile of women with GDM.
JOURNAL OF PERINATAL MEDICINE
(2022)
Letter
Public, Environmental & Occupational Health
America Aime Corona-Gutierrez, Eva Elizabet Camarena-Pulido, Juan Pablo Arellano-Cardenas, Mireya Robledo-Aceves, Claudia Angelica Quezada-Salazar, Larissa Maria Gomez-Ruiz, Rene Oswaldo Perez-Ramirez
SALUD PUBLICA DE MEXICO
(2022)
Letter
Public, Environmental & Occupational Health
Helix Ivan Barajas-Calderon, Mireya Robledo-Aceves, Patricia Paredes-Casillas, Ana Cristina Aguirre-Espinosa, America Aime Corona-Gutierrez, Eva Elizabeth Camarena-Pulido
SALUD PUBLICA DE MEXICO
(2021)
Article
Urology & Nephrology
Jonathan S. Chavez-Iniguez, Jorge L. Poo, Miguel Ibarra-Estrada, Leonel Garcia-Benavides, Guillermo Navarro-Blackaller, Cynthia Cervantes-Sanchez, Eduardo Nungaray-Pacheco, Ramon Medina-Gonzalez, Juan Armendariz-Borunda, Guillermo Garcia-Garcia
Summary: In patients with septic acute kidney injury (sAKI), prolonged-release pirfenidone (PR-PFD) did not improve the clinical course of sAKI and appeared to be safe in terms of adverse events.
INTERNATIONAL JOURNAL OF NEPHROLOGY
(2021)
Article
Medicine, Research & Experimental
Natali Vega-Magana, Antonio Galiana, Luis Felipe Jave-Suarez, Leonel Garcia-Benavides, Susana del Toro-Arreola, Jaime Federico Andrade-Villanueva, Luz Alicia Gonzalez-Hernandez, Rosa Cremades, Adriana Aguilar-Lemarroy, Maria Guadalupe Flores-Miramontes, Jesse Haramati, Jesus Meza-Arroyo, Miriam Ruth Bueno-Topete
IRANIAN JOURNAL OF BASIC MEDICAL SCIENCES
(2020)