Article
Oncology
Tamara V. Azizova, Evgeny V. Bragin, Maria V. Bannikova, Nobuyuki Hamada, Evgeniya S. Grigoryeva
Summary: This study reports an increased risk of normal-tension glaucoma (NTG) in radiation workers exposed to chronic doses greater than 1Gy. If confirmed in other cohorts, this finding has significant implications for normal tissue complications in radiotherapy patients and ocular radiation protection in radiation workers.
Article
Biology
Daniel O. Stram, Mikhail Sokolnikov, Bruce A. Napier, Vadim V. Vostrotin, Alexander Efimov, Dale L. Preston
Summary: This study re-examined lung cancer mortality rates among workers at the Mayak nuclear facility in Russia, finding that both external gamma-ray and internal plutonium exposures significantly increased lung cancer incidence rates when considering dose uncertainty.
RADIATION RESEARCH
(2021)
Article
Ophthalmology
Aaron B. Beasley, David B. Preen, Samuel McLenachan, Elin S. Gray, Fred K. Chen
Summary: This study estimated the incidence and mortality of conjunctival melanoma in Australia from 1982 to 2014. The incidence rates increased over the study period, while disease survival remained unchanged at a mean of 90%.
INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE
(2023)
Article
Public, Environmental & Occupational Health
Jeri L. Anderson, Stephen J. Bertke, James Yiin, Kaitlin Kelly-Reif, Robert Douglas Daniels
Summary: The study examined the dose-response relationships between radiation absorbed dose to the lung from uranium and external sources and circulatory system disease mortality in US uranium enrichment workers. The results indicated a modestly increased risk of ischaemic heart disease mortality with high internal uranium lung dose and significantly increased risk with external dose exceeding 150 mGy. Non-linear dose-response models showed sublinear responses, suggesting linear models may not accurately describe the association between uranium dose and circulatory system disease mortality.
OCCUPATIONAL AND ENVIRONMENTAL MEDICINE
(2021)
Article
Multidisciplinary Sciences
Tamara V. Azizova, Evgeniya S. Grigoryeva, Nobuyuki Hamada
Summary: Research shows that there is a correlation between radiation dose rate and the risk of mortality from ischemic heart disease among occupationally chronically exposed workers. The risk increases with higher dose rates, and also with longer duration of exposure at high rates. These findings contribute to the scientific basis for recommendations on the radiation protection system.
SCIENTIFIC REPORTS
(2023)
Article
Public, Environmental & Occupational Health
Anthony Del Monaco, Christina Dimitriadis, Sophia Xie, Geza Benke, Malcolm Ross Sim, Karen Walker-Bone
Summary: This study investigated mortality and incident cancer rates among aluminium industry workers. The results showed that production workers had a higher risk of lung, mesothelioma, prostate, and liver cancer. Maintenance workers had a higher risk of stomach cancer and Alzheimer's disease. Overall, the mortality rate of aluminium industry workers was similar to that of the Australian general population.
OCCUPATIONAL AND ENVIRONMENTAL MEDICINE
(2023)
Article
Biology
Tamara Azizova, Maria B. Moseeva, Evgeniya S. Grigoryeva, Nobuyuki Hamada
Summary: This study reports the incidence risks for cerebrovascular diseases and strokes in a cohort of Russian nuclear workers chronically exposed to ionizing radiation. The findings suggest a significant association between cumulative radiation dose and CeVD incidence, but no significant association with stroke or its types.
RADIATION AND ENVIRONMENTAL BIOPHYSICS
(2022)
Article
Multidisciplinary Sciences
Julie Lopes, Clemence Baudin, Juliette Feuardent, Herve Roy, Sylvaine Caer-Lorho, Klervi Leuraud, Marie-Odile Bernier
Summary: Medical personnel in France are occupationally exposed to ionizing radiation, but no study has been conducted to investigate the health risks associated with this exposure. The ORICAMs cohort is a nationwide French longitudinal study that aims to assess the risk of radiation-associated cancer and non-cancer mortality in medical workers. The cohort includes workers monitored for ionizing radiation exposure from 2002 to 2012. Initial analysis shows that the mortality rate among these workers is significantly lower than the national reference rates, but further research is needed to establish a potential relationship between occupational exposure and mortality risk.
Article
Biology
Tamara Azizova, Maria Bannikova, Ksenia Briks, Evgeniya S. Grigoryeva, Nobuyuki Hamada
Summary: Heart diseases are a major cause of death. A study on a cohort of Russian nuclear workers revealed that chronic occupational exposure to external gamma and/or internal alpha radiation is associated with an increased risk of certain types of heart diseases. Linear model analysis showed a positive correlation between the risks and gamma radiation dose, which remained significant after adjusting for non-radiation factors.
RADIATION AND ENVIRONMENTAL BIOPHYSICS
(2023)
Article
Environmental Sciences
Tamara Azizova, Maria Bannikova, Evgeniya S. Grigoryeva, Ksenia Briks, Nobuyuki Hamada
Summary: This study investigated mortality from diseases of the circulatory system (DCS) in Russian nuclear workers and found no significant associations between mortality and gamma-ray exposure or internal exposure to plutonium. However, a significant association was observed between gamma-ray exposure and mortality from ischemic stroke in male workers in the subcohort. Positive associations were also found between internal exposure and mortality from DCS and ischemic heart disease (IHD) in women.
JOURNAL OF RADIOLOGICAL PROTECTION
(2022)
Article
Oncology
Lucia Cayuela, Anna Michela Gaeta, Jose Luis Lopez-Campos, Rocio Reinoso-Arija, Aurelio Cayuela
Summary: The aim of this study was to analyze the age-period-cohort effects on lung cancer mortality in Spain from 1982 to 2021. The results showed a steady decline in relative risk among male birth cohorts since 1922, while there was a strong cohort effect observed in women. The period relative risk decreased in men from 1987 to 1991, while increasing in women during the same period.
Article
Infectious Diseases
Camille Bouchand, Anais Andreo, Florence Le Gallou, Stephane Corvec, Celine Bourigault, Didier Lepelletier
Summary: The retrospective study conducted from 2005 to 2019 showed a significant increase in the incidence density of E-ESBL infections over a 17-year period in the university hospital. Patients with E-ESBL bacteremia had a higher mortality rate, highlighting the importance of continued efforts to control the spread of these multidrug-resistant bacteria in the institution.
EUROPEAN JOURNAL OF CLINICAL MICROBIOLOGY & INFECTIOUS DISEASES
(2022)
Article
Public, Environmental & Occupational Health
Karen Walker-Bone, Geza Benke, Ewan MacFarlane, S. Klebe, Ken Takahashi, Fraser Brims, Malcolm Ross Sim, Tim R. Driscoll
Summary: Mesothelioma, a rare and deadly cancer associated with asbestos exposure, continues to be diagnosed in Australia despite the ban on asbestos since 2003. The Australian Mesothelioma Registry was established to gather comprehensive data on incidence, mortality, and asbestos exposure. Results show a decline in incidence and mortality rates due to effective control of occupational asbestos use, but the rates among women remain stable, suggesting other sources of exposure.
OCCUPATIONAL AND ENVIRONMENTAL MEDICINE
(2023)
Article
Biology
Nezahat Hunter, Richard G. E. Haylock, Michael Gillies, Wei Zhang
Summary: This study examines the relationship between long-term low-dose external radiation exposure and solid cancer incidence. The findings show a strong association between external dose and solid cancers in individuals only exposed to external radiation, which remains linear when accounting for smoking. Furthermore, there is a statistically significant increasing trend for colorectal, bladder, and pleural cancer with radiation dose.
RADIATION RESEARCH
(2022)
Article
Environmental Sciences
L. de Graaf, M. Talibov, M. Boulanger, M. Bureau, E. Robelot, P. Lebailly, I. Baldi
Summary: This study analyzed causes of death, prevalence of non-cancer diseases, and incidence of major cancers among greenspace workers. The study found that male greenspace workers were more likely to have a history of allergic diseases and depression compared to farmers and non-agricultural workers. Male greenspace workers also had a slightly higher risk of mortality from ischemic cardiological diseases. Additionally, male greenspace workers had higher incidence rates of overall cancer, prostate cancer, thyroid cancer, testicular cancer, and skin melanoma. Female greenspace workers had a higher risk of breast cancer compared to farmers.
ENVIRONMENTAL RESEARCH
(2022)
Article
Environmental Sciences
Tamara Azizova, Evgeniya Grigoryeva, Galina Zhuntova, Evgeniya Kirillova, Christopher Loffredo
Summary: Findings from animal experiments and epidemiological studies show contradictory conclusions about the effects of ionizing radiation on offspring. This paper introduces a database of families of workers from the Mayak nuclear facility, which could be used for investigating non-targeted and transgenerational radiation effects on offspring of exposed parents.
Review
Biology
Mark P. Little, Tamara Azizova, Nobuyuki Hamada
Summary: Studies have shown correlations between ionizing radiation and circulatory diseases, cataracts, and other ocular endpoints, with dose-response relationships observed. Additionally, neurological detriment may occur following radiation exposure at low-moderate doses.
INTERNATIONAL JOURNAL OF RADIATION BIOLOGY
(2021)
Article
Biology
Tamara V. Azizova, Maria V. Bannikova, Evgeniya S. Grigoryeva, Valentina L. Rybkina
Summary: The study found that occupational exposure to low dose-rate ionizing radiation at the Russian nuclear facility Mayak Production Association (PA) increases the risk of basal cell carcinoma (BCC), but does not significantly affect the risk of squamous cell carcinoma (SCC). Gender, age at hire, attained age, and facility type did not have a significant impact on the incidence risk of BCC and SCC.
RADIATION AND ENVIRONMENTAL BIOPHYSICS
(2021)
Article
Environmental Sciences
Tamara Azizova, Maria Bannikova, Evgeniya S. Grigoryeva, Ksenia Briks, Nobuyuki Hamada
Summary: This study investigated mortality from diseases of the circulatory system (DCS) in Russian nuclear workers and found no significant associations between mortality and gamma-ray exposure or internal exposure to plutonium. However, a significant association was observed between gamma-ray exposure and mortality from ischemic stroke in male workers in the subcohort. Positive associations were also found between internal exposure and mortality from DCS and ischemic heart disease (IHD) in women.
JOURNAL OF RADIOLOGICAL PROTECTION
(2022)
Article
Biology
Tamara Azizova, Maria B. Moseeva, Evgeniya S. Grigoryeva, Nobuyuki Hamada
Summary: This study reports the incidence risks for cerebrovascular diseases and strokes in a cohort of Russian nuclear workers chronically exposed to ionizing radiation. The findings suggest a significant association between cumulative radiation dose and CeVD incidence, but no significant association with stroke or its types.
RADIATION AND ENVIRONMENTAL BIOPHYSICS
(2022)
Editorial Material
Biology
Elizabeth A. Ainsbury, Claudia Dalke, Mariateresa Mancuso, Munira Kadhim, Roy A. Quinlan, Tamara Azizova, Lawrence T. Dauer, Joseph R. Dynlacht, Rick Tanner, Nobuyuki Hamada
Summary: Recent studies have shown that the lens of the eye is more sensitive to radiation than previously believed, leading to a reduction in occupational lens dose limits in the European Union countries, Japan, and elsewhere. This Commentary introduces the work of the LDLensRad Consortium in advancing the understanding of the mechanisms of low dose radiation cataract.
RADIATION RESEARCH
(2022)
Article
Oncology
Tamara V. Azizova, Evgeny V. Bragin, Maria V. Bannikova, Nobuyuki Hamada, Evgeniya S. Grigoryeva
Summary: This study reports an increased risk of normal-tension glaucoma (NTG) in radiation workers exposed to chronic doses greater than 1Gy. If confirmed in other cohorts, this finding has significant implications for normal tissue complications in radiotherapy patients and ocular radiation protection in radiation workers.
Article
Biology
Tamara Azizova, Maria Bannikova, Ksenia Briks, Evgeniya S. Grigoryeva, Nobuyuki Hamada
Summary: Heart diseases are a major cause of death. A study on a cohort of Russian nuclear workers revealed that chronic occupational exposure to external gamma and/or internal alpha radiation is associated with an increased risk of certain types of heart diseases. Linear model analysis showed a positive correlation between the risks and gamma radiation dose, which remained significant after adjusting for non-radiation factors.
RADIATION AND ENVIRONMENTAL BIOPHYSICS
(2023)
Article
Hematology
T. Azizova, E. Bragin, M. Bannikova, E. S. Grigoryeva, A. Korobkin
Summary: This study aimed to assess the incidence and mortality rates of malignant neoplasms of the hematopoietic and lymphoid tissues (HLTT) in workers chronically exposed to occupational ionizing radiation. The results showed that the rates were associated with sex, attained age, and follow-up period, with higher rates in males compared to females. The study also revealed an increasing trend in the incidence rates of chronic leukemia and lymphoma by the end of the follow-up period.
GEMATOLOGIYA I TRANSFUZIOLOGIYA
(2023)
Article
Environmental Sciences
Sergey Osovets, Tamara Azizova, Maria B. Moseeva
Summary: This study aimed to estimate threshold doses and uncertainties for human health effects after short-term high-dose-rate radiation exposure. Results showed that the effective dose threshold technique provided more accurate and statistically significant threshold dose estimates compared to the quantile technique, which had higher relative uncertainties.
RADIATION PROTECTION DOSIMETRY
(2023)