Germline ESR2 mutation predisposes to medullary thyroid carcinoma and causes up-regulation of RET expression

Cross-laboratory validation of the OncoScan® FFPE Assay, a multiplex tool for whole genome tumour profiling

(2015) Joseph M Foster et al.   BMC Medical Genomics

Revised American Thyroid Association Guidelines for the Management of Medullary Thyroid Carcinoma

(2015) Samuel A. Wells et al.   THYROID

Germline Mutations in the CDKN2B Tumor Suppressor Gene Predispose to Renal Cell Carcinoma

(2015) M. Jafri et al.   Cancer Discovery

Inhibition of RET Increases the Efficacy of Antiestrogen and Is a Novel Treatment Strategy for Luminal Breast Cancer

(2014) P. M. Spanheimer et al.   CLINICAL CANCER RESEARCH

Phaeochromocytoma and paraganglioma: next-generation sequencing and evolving Mendelian syndromes

(2014) E. R. Maher   CLINICAL MEDICINE

Realizing the promise of cancer predisposition genes

(2014) Nazneen Rahman   NATURE

Ponatinib (AP24534) Is a Novel Potent Inhibitor of Oncogenic RET Mutants Associated With Thyroid Cancer

(2013) Valentina De Falco et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Multiple Endocrine Neoplasia Type 2 and Familial Medullary Thyroid Carcinoma: An Update

(2013) Samuel A. Wells et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Exomic Sequencing of Medullary Thyroid Cancer Reveals Dominant and Mutually Exclusive Oncogenic Mutations inRETandRAS

(2012) Nishant Agrawal et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Vandetanib in Patients With Locally Advanced or Metastatic Medullary Thyroid Cancer: A Randomized, Double-Blind Phase III Trial

(2011) Samuel A. Wells et al.   JOURNAL OF CLINICAL ONCOLOGY

RET in breast cancer: functional and therapeutic implications

(2011) Andrea Morandi et al.   TRENDS IN MOLECULAR MEDICINE

Multiple endocrine neoplasia type 2 syndromes (MEN 2): results from the ItaMEN network analysis on the prevalence of different genotypes and phenotypes

(2010) Cristina Romei et al.   EUROPEAN JOURNAL OF ENDOCRINOLOGY

Multiple endocrine neoplasia type 2RETprotooncogene database: Repository of MEN2-associatedRETsequence variation and reference for genotype/phenotype correlations

(2009) Rebecca L. Margraf et al.   HUMAN MUTATION

A novel mechanism of sodium iodide symporter repression in differentiated thyroid cancer

(2009) V. E. Smith et al.   JOURNAL OF CELL SCIENCE

The Ret Receptor Tyrosine Kinase Pathway Functionally Interacts with the ER  Pathway in Breast Cancer

(2008) A. Boulay et al.   CANCER RESEARCH

Loss of estrogen receptor β isoform expression and its correlation with aberrant DNA methylation of the 5′-untranslated region in human epithelial ovarian carcinoma

(2008) Fumihiko Suzuki et al.   CANCER SCIENCE

The emerging landscape of breast cancer susceptibility

(2007) Michael R Stratton et al.   NATURE GENETICS