Review
Biochemistry & Molecular Biology
William Torregrossa, Michele Torrisi, Rosaria De Luca, Carmela Casella, Carmela Rifici, Mirjam Bonanno, Rocco Salvatore Calabro
Summary: Traumatic brain injury is damage to the brain occurring after birth, resulting in deterioration of cognitive, behavioural, and emotional functions. Neuropsychological evaluation can assist clinicians in assessing the patient's condition, reaching differential diagnoses, and developing intervention strategies. However, it is difficult to determine the most suitable assessment tool for different brain injury conditions considering the various rating scales available.
Article
Clinical Neurology
Elke Butterbrod, Margriet Sitskoorn, Marjan Bakker, Bernadette Jakobs, Ruth Fleischeuer, Janine Roijers, Geert-Jan Rutten, Karin Gehring
Summary: This study found no significant differences in pretreatment cognitive performance or cognitive decline within 1 year after surgery between APOE epsilon 4 carriers and non-carriers with meningioma and glioma. Larger samples with longer-term follow-up are recommended for further investigation of potential late treatment effects.
EUROPEAN JOURNAL OF NEUROLOGY
(2021)
Article
Behavioral Sciences
Yaning Wang, Wenlin Chen, Tianrui Yang, Binghao Zhao, Lizhou Zhou, Ziren Kong, Yuekun Wang, Congxin Dai, Yu Wang, Wenbin Ma
Summary: Patients with malignant intracranial tumors experienced a significant decrease in quality of life and daily living ability 7 days after surgery, but recovered by 1 month post-surgery. Patients with left hemisphere lesions showed worse cognitive function and ADL was associated with short-term prognosis.
BRAIN AND BEHAVIOR
(2021)
Article
Rehabilitation
Amanda Sacks-Zimmerman, Thomas F. Bergquist, Ellen M. Farr, Melinda A. Cornwell, Dora Kanellopoulos
Summary: "Long COVID," a term used to describe persistent symptoms following COVID-19 infection, shares similarities with other postviral syndromes. The neuropsychiatric symptoms associated with long COVID can have a lasting impact on quality of life and functioning. Rehabilitation professionals can address these symptoms within the biopsychosocial framework of chronic illness, but current practice models are not equipped to handle concurrent psychiatric and cognitive symptoms in adults with long COVID. Therefore, this article presents a biopsychosocial framework for long COVID and provides evidence-based treatment strategies drawn from existing literature on chronic postviral illnesses.
ARCHIVES OF PHYSICAL MEDICINE AND REHABILITATION
(2023)
Article
Neurosciences
Detao Meng, Zhaohui Jin, Yixuan Wang, Boyan Fang
Summary: The study aimed to investigate the effect of neuropsychiatric symptoms on cognitive decline in patients with Parkinson's disease. Longitudinal data from the Parkinson's Progression Markers Initiative cohort were analyzed using linear mixed-effects models and generalized estimating equations. The results showed that depression, anxiety, apathy, and psychosis were associated with global cognitive decline, and patients with these symptoms were more likely to meet the criteria for mild cognitive impairment.
CNS NEUROSCIENCE & THERAPEUTICS
(2023)
Article
Psychiatry
Zhenguo Wu, Guanli Su, Wenting Lu, Lin Liu, Zixuan Zhou, Bingchuan Xie
Summary: The study aimed to evaluate the correlation between clinical symptoms and cognitive impairment in elderly patients with depressive disorder. The results showed that the incidence of severe cognitive impairment was significantly higher in the combined group than in the depressive disorder group, and the combined group had more severe somatic symptoms, suicidal tendency, retardation of thinking, diminution of energy, anxiety, and sleep disorder compared to the depressive disorder group. Spearman rank correlation analysis demonstrated a negative correlation between somatic symptoms, mood change, suicidal tendency, retardation of thinking, diminution of energy, anxiety, sleep disorder, and cognitive impairment.
FRONTIERS IN PSYCHIATRY
(2022)
Article
Clinical Neurology
Katarzyna Kujawa, Alina Zurek, Agata Goraczko, Grzegorz Zurek
Summary: This study evaluates memory function in consciousness impaired patients using eye tracking technology, demonstrating its potential for assessing cognitive function in individuals with brain damage.
FRONTIERS IN NEUROLOGY
(2022)
Article
Geriatrics & Gerontology
Zehua Wang, Ke Ren, Deyu Li, Zeping Lv, Xiang Li, Xiaoli He, Daifa Wang, Wenyu Jiang
Summary: This study explores the changes in gait and brain co-functional connectivity between cognitively healthy and cognitively impaired groups under dual-task walking. The results show that there were no significant differences in overall functional connectivity and gait performance during single-task walking between the two groups, but the cognitively impaired group was more affected by dual-task walking.
FRONTIERS IN AGING NEUROSCIENCE
(2022)
Review
Immunology
Yichen Cai, Pan Liu, Xiaolan Zhou, Jun Yuan, Qiu Chen
Summary: Obesity is a complex metabolic disease, and cognitive impairment is a significant complication. The gut microbiota differs between individuals with and without obesity, and the microbial-gut-brain axis is an essential pathway through which obesity affects the brain. Probiotics have been shown to alleviate symptoms associated with obesity and neurobehavioral disorders.
FRONTIERS IN CELLULAR AND INFECTION MICROBIOLOGY
(2023)
Article
Clinical Neurology
Vincenzo Rizzo, Carmen Terranova, Giovanni Raffa, Salvatore Massimiliano Cardali, Filippo Flavio Angileri, Giuseppina Marzano, Maria Catena Quattropani, Antonino Germano, Paolo Girlanda, Angelo Quartarone
Summary: Brain tumors can lead to abnormal cortical excitability in affected hemispheres, with decreased SICI, ICF, and SAI. Further research is needed to investigate the relationship between cortical excitability and motor impairment in these patients.
FRONTIERS IN NEUROLOGY
(2021)
Article
Hematology
Sirui Ma, Rushad Patell, Eric Miller, Siyang Ren, Josue Marquez-Garcia, Samuel Panoff, Ria Sharma, Amanda Pinson, Pavania Elavalakanar, Grif fin Weber, Erik Uhlmann, Donna Neuberg, Salil Soman, Jeffrey I. Zwicker
Summary: This study found no increased risk of intracranial hemorrhage in patients with primary brain tumors exposed to antiplatelet medications, based on a matched retrospective cohort study.
JOURNAL OF THROMBOSIS AND HAEMOSTASIS
(2023)
Article
Immunology
Maria I. Dominguez-Mozo, Ignacio Casanova, Laura De Torres, Yolanda Aladro-Benito, Silvia Perez-Perez, Angel Garcia-Martinez, Patricia Gomez, Sara Abellan, Esther De Antonio, Carlos Lopez-De-Silanes, Roberto Alvarez-Lafuente
Summary: This study found correlations between serum microRNAs expression and disability, cognitive functioning, and brain volume in patients with remitting-relapsing multiple sclerosis, supporting the hypothesis that microRNAs could be potential biomarkers for this disease.
FRONTIERS IN IMMUNOLOGY
(2022)
Review
Oncology
Milena Pertz, Uwe Schlegel, Patrizia Thoma
Summary: Research has shown that sociocognitive functioning is closely related to quality of life and treatment outcomes in brain tumor patients. As neuro-oncological treatment becomes more effective, the preservation and improvement of quality of life have become important goals. However, sociocognitive functioning has been relatively neglected in previous research. This article reviews the literature on psychosocial burden and sociocognitive functioning in adult brain tumor patients.
Article
Biochemistry & Molecular Biology
Chin-Hsiao Tseng
Summary: This study investigated the association between metformin use and malignant brain tumors in patients with type 2 diabetes mellitus. The results showed a reduction in risk of malignant brain tumors associated with metformin use, especially after approximately 2-5 years of use.
Article
Multidisciplinary Sciences
Enoch Chang, Marina Joel, Hannah Y. Chang, Justin Du, Omaditya Khanna, Antonio Omuro, Veronica Chiang, Sanjay Aneja
Summary: Through comparing mathematical methods, it was found that the weighted average of the largest three metastases had the highest concordance index across different survival models in patients with multifocal brain metastases. This suggests that radiomic features can be effectively combined to estimate patient-level outcomes.
SCIENTIFIC REPORTS
(2021)