FM19G11 reverses endothelial dysfunction in rat and human arteries through stimulation of the PI3K/Akt/eNOS pathway, independently of mTOR/HIF-1α activation
出版年份 2015 全文链接
标题
FM19G11 reverses endothelial dysfunction in rat and human arteries through stimulation of the PI3K/Akt/eNOS pathway, independently of mTOR/HIF-1α activation
作者
关键词
-
出版物
BRITISH JOURNAL OF PHARMACOLOGY
Volume 172, Issue 5, Pages 1277-1291
出版商
Wiley
发表日期
2014-11-03
DOI
10.1111/bph.12993
参考文献
相关参考文献
注意：仅列出部分参考文献，下载原文获取全部文献信息。- Differential Regulation of Pulmonary Vascular Cell Growth by Hypoxia-Inducible Transcription Factor–1α and Hypoxia-Inducible Transcription Factor–2α
- (2013) Aftab Ahmad et al. AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY
- The Concise Guide to PHARMACOLOGY 2013/14: Enzymes
- (2013) Stephen P.H. Alexander et al. BRITISH JOURNAL OF PHARMACOLOGY
- Ca2+-activated K+channel (KCa) stimulation improves relaxant capacity of PDE5 inhibitors in human penile arteries and recovers the reduced efficacy of PDE5 inhibition in diabetic erectile dysfunction
- (2013) R González-Corrochano et al. BRITISH JOURNAL OF PHARMACOLOGY
- Oxygen-independent Regulation of HIF-1: Novel Involvement of PI3K/ AKT/mTOR Pathway in Cancer
- (2013) Faton Agani et al. CURRENT CANCER DRUG TARGETS
- A Systematic Review of the Association Between Erectile Dysfunction and Cardiovascular Disease
- (2013) Giorgio Gandaglia et al. EUROPEAN UROLOGY
- Impaired cross-activation of β3 integrin and VEGFR-2 on endothelial progenitor cells with aging decreases angiogenesis in response to hypoxia
- (2013) Qun Di et al. INTERNATIONAL JOURNAL OF CARDIOLOGY
- Erectile dysfunction and asymptomatic coronary artery disease: frequently detected by computed tomography coronary angiography but not by exercise electrocardiography
- (2013) G. Jackson INTERNATIONAL JOURNAL OF CLINICAL PRACTICE
- Peripheral atherosclerosis in patients with arterial erectile dysfunction
- (2013) C Goksu et al. INTERNATIONAL JOURNAL OF IMPOTENCE RESEARCH
- The IUPHAR/BPS Guide to PHARMACOLOGY: an expert-driven knowledgebase of drug targets and their ligands
- (2013) Adam J. Pawson et al. NUCLEIC ACIDS RESEARCH
- Insulin Resistance and Coronary Heart Disease in Nondiabetic Individuals
- (2012) Gerald Reaven ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY
- Ceramide Mediates Vascular Dysfunction in Diet-Induced Obesity by PP2A-Mediated Dephosphorylation of the eNOS-Akt Complex
- (2012) Q.-J. Zhang et al. DIABETES
- FM19G11 Favors Spinal Cord Injury Regeneration and Stem Cell Self-Renewal by Mitochondrial Uncoupling and Glucose Metabolism Induction
- (2012) Francisco Javier Rodríguez-Jiménez et al. STEM CELLS
- Hypoxia-Inducible Factor 1 Alpha Contributes to Cardiac Healing in Mesenchymal Stem Cells-Mediated Cardiac Repair
- (2012) Inmaculada Cerrada et al. STEM CELLS AND DEVELOPMENT
- Rapamycin inhibits hydrogen peroxide-induced loss of vascular contractility
- (2011) Ge Gao et al. AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY
- Flow-Mediated Dilation and Cardiovascular Event Prediction
- (2011) Daniel J. Green et al. HYPERTENSION
- Fasting and Post-Glucose Load Measures of Insulin Resistance and Risk of Ischemic Stroke in Older Adults
- (2011) Evan L. Thacker et al. STROKE
- Guidelines for reporting experiments involving animals: the ARRIVE guidelines
- (2010) JC McGrath et al. BRITISH JOURNAL OF PHARMACOLOGY
- Animal research: Reporting in vivo experiments: The ARRIVE guidelines
- (2010) Carol Kilkenny et al. BRITISH JOURNAL OF PHARMACOLOGY
- FM19G11: A new modulator of HIF that links mTOR activation with the DNA damage checkpoint pathways
- (2010) Francisco Javier Rodríguez-Jiménez et al. CELL CYCLE
- Hypoxia-inducible factor-1 improves inotropic responses of cardiac myocytes in ageing heart without affecting mitochondrial activity
- (2010) Tao Tan et al. EXPERIMENTAL PHYSIOLOGY
- Anatomy, Physiology, and Pathophysiology of Erectile Dysfunction
- (2010) Christian Gratzke et al. Journal of Sexual Medicine
- Hypoxia-Inducible Factors and the Response to Hypoxic Stress
- (2010) Amar J. Majmundar et al. MOLECULAR CELL
- Cellular signaling and NO production
- (2010) Thomas Michel et al. PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY
- Endothelial dysfunction in aged humans is related with oxidative stress and vascular inflammation
- (2009) Leocadio Rodríguez-Mañas et al. AGING CELL
- Contribution of Insulin and Akt1 Signaling to Endothelial Nitric Oxide Synthase in the Regulation of Endothelial Function and Blood Pressure
- (2009) J. David Symons et al. CIRCULATION RESEARCH
- Vascular insulin resistance in prehypertensive rats: Role of PI3-kinase/Akt/eNOS signaling
- (2009) Rong Li et al. EUROPEAN JOURNAL OF PHARMACOLOGY
- FM19G11, a New Hypoxia-inducible Factor (HIF) Modulator, Affects Stem Cell Differentiation Status
- (2009) Victoria Moreno-Manzano et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Diabetes Exacerbates the Functional Deficiency of NO/cGMP Pathway Associated with Erectile Dysfunction in Human Corpus Cavernosum and Penile Arteries
- (2009) Javier Angulo et al. Journal of Sexual Medicine
- The fructose-fed rat: a review on the mechanisms of fructose-induced insulin resistance and hypertension
- (2009) Linda T. Tran et al. MOLECULAR AND CELLULAR BIOCHEMISTRY
- Insulin resistance functionally limits endothelium-dependent coronary vasodilation in nondiabetic patients
- (2008) Noriyuki Fujii et al. HEART AND VESSELS
- Differential Dependence of Hypoxia-inducible Factors 1α and 2α on mTORC1 and mTORC2
- (2008) Alfredo Toschi et al. JOURNAL OF BIOLOGICAL CHEMISTRY
Discover Peeref hubs
Discuss science. Find collaborators. Network.
Join a conversationCreate your own webinar
Interested in hosting your own webinar? Check the schedule and propose your idea to the Peeref Content Team.
Create Now