Selected ginsenosides of the protopanaxdiol series are novel positive allosteric modulators of P2X7 receptors

Probenecid Blocks Human P2X7 Receptor-Induced Dye Uptake via a Pannexin-1 Independent Mechanism

(2014) Archana Bhaskaracharya et al.   PLoS One

Ginseng ginsenoside pharmacology in the nervous system: involvement in the regulation of ion channels and receptors

(2014) Seung-Yeol Nah   Frontiers in Physiology

20(S)-Protopanaxadiol Triggers Mitochondrial-Mediated Apoptosis in Human Lung Adenocarcinoma A549 Cells via Inhibiting the PI3K/Akt Signaling Pathway

(2013) Yun-Long Zhang et al.   AMERICAN JOURNAL OF CHINESE MEDICINE

Cathelicidin antimicrobial peptide inhibits fibroblast migration via P2X7 receptor signaling

(2013) Shohei Kumagai et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

The Concise Guide to PHARMACOLOGY 2013/14: Ligand-Gated Ion Channels

(2013) Stephen P.H. Alexander et al.   BRITISH JOURNAL OF PHARMACOLOGY

The Concise Guide to PHARMACOLOGY 2013/14: Ion Channels

(2013) Stephen P.H. Alexander et al.   BRITISH JOURNAL OF PHARMACOLOGY

Ginsenoside Rg3 regulates GABAA receptor channel activity: Involvement of interaction with the γ2 subunit

(2013) Byung-Hwan Lee et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Ginsenoside Rd induces protective anti-Candida albicans antibody through immunological adjuvant activity

(2013) Yongmoon Han et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

The IUPHAR/BPS Guide to PHARMACOLOGY: an expert-driven knowledgebase of drug targets and their ligands

(2013) Adam J. Pawson et al.   NUCLEIC ACIDS RESEARCH

Development and validation of an LC-MS/MS method for determination of compound K in human plasma and clinical application

(2013) Jung Soo Kim et al.   Journal of Ginseng Research

Ginsenoside Rg1 prevents SK-N-SH neuroblastoma cell apoptosis induced by supernatant from Aβ1–40-stimulated THP-1 monocytes

(2012) Wei Li et al.   BRAIN RESEARCH BULLETIN

Positive allosteric modulation by ivermectin of human but not murine P2X7 receptors

(2012) W Nörenberg et al.   BRITISH JOURNAL OF PHARMACOLOGY

Transient P2X 7 Receptor Activation Triggers Macrophage Death Independent of Toll-like Receptors 2 and 4, Caspase-1, and Pannexin-1 Proteins

(2012) Peter J. Hanley et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Involvement of the P2X7Purinergic Receptor and c-Jun N-Terminal and Extracellular Signal-Regulated Kinases in Cyclooxygenase-2 and Prostaglandin E2Induction by LL-37

(2012) Pareena Chotjumlong et al.   Journal of Innate Immunity

Effects of Ginsenoside Metabolites on GABAAReceptor-Mediated Ion Currents

(2012) Byung-Hwan Lee et al.   Journal of Ginseng Research

Clemastine Potentiates the Human P2X7 Receptor by Sensitizing It to Lower ATP Concentrations

(2011) Wolfgang Nörenberg et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Transient receptor potential vanilloid-1 participates in the inhibitory effect of ginsenoside Rg1 on capsaicin-induced interleukin-8 and prostaglandin E2production in HaCaT cells

(2011) Jin Huang et al.   JOURNAL OF PHARMACY AND PHARMACOLOGY

Differential Effects of Ginsenoside Metabolites on HERG K+Channel Currents

(2011) Sun-Hye Choi et al.   Journal of Ginseng Research

Guidelines for reporting experiments involving animals: the ARRIVE guidelines

(2010) JC McGrath et al.   BRITISH JOURNAL OF PHARMACOLOGY

Animal research: Reporting in vivo experiments: The ARRIVE guidelines

(2010) Carol Kilkenny et al.   BRITISH JOURNAL OF PHARMACOLOGY

Panax ginseng has anti-infective activity against opportunistic pathogen Pseudomonas aeruginosa by inhibiting quorum sensing, a bacterial communication process critical for establishing infection

(2010) Z. Song et al.   PHYTOMEDICINE

Protopanaxadiol and protopanaxatriol bind to glucocorticoid and oestrogen receptors in endothelial cells

(2009) Kar Wah Leung et al.   BRITISH JOURNAL OF PHARMACOLOGY

The Human Cathelicidin LL-37 Modulates the Activities of the P2X7Receptor in a Structure-dependent Manner

(2008) Linda Tomasinsig et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Panax ginseng ginsenoside-Rg2 protects memory impairment via anti-apoptosis in a rat model with vascular dementia

(2007) Guizhi Zhang et al.   JOURNAL OF ETHNOPHARMACOLOGY