Article
Multidisciplinary Sciences
Anna-Clara Esbjornsson, Arne Johansson, Hanneke Andriesse, Henrik Wallander
Summary: This study aimed to estimate the birth prevalence of children born with isolated or non-isolated clubfoot in Sweden and describe the characteristics of the clubfoot population. Data from a national register was used to calculate the birth prevalence, which was found to be 1.24/1000 live births for isolated clubfoot and 1.35/1000 live births for non-isolated clubfoot. Children with non-isolated clubfoot had more severe deformities and atypical signs compared to those with isolated clubfoot. These findings can be used for planning clubfoot treatment and evaluating trends in clubfoot birth prevalence.
Article
Chemistry, Multidisciplinary
Dannica C. Wall, Dana Dittoe, Ramon D. Malherios, Kenneth E. Anderson, Nick Anthony
Summary: This study identified and evaluated differences in microbiome compositions of the ileum and ceca of white leghorn genetic strains from 1940 and 2016. The research found that genetic lineage did not significantly affect microbiome diversity, but genetic makeup in combination with nutritional composition influenced the microbiota in the ceca and ileal of the hens.
APPLIED SCIENCES-BASEL
(2023)
Article
Immunology
Behzad Naderalvojoud, Nilpa D. Shah, Jane N. Mutanga, Artur Belov, Rebecca Staiger, Jonathan H. Chen, Barbee Whitaker, Tina Hernandez-Boussard
Summary: This study characterizes influenza vaccination rates among Medicaid enrollees in the U.S. and investigates factors influencing vaccine uptake. The study found that vaccination rates increased during the COVID-19 period, with children having the highest rates and adults having the lowest rates. Factors such as gender, residency, and Medicaid-managed care affiliation influenced vaccine uptake positively, while mental health and substance abuse disorders decreased the likelihood of vaccination.
Article
Biology
Khai C. Ang, Victor A. Canfield, Tiffany C. Foster, Thaddeus D. Harbaugh, Kathryn A. Early, Rachel L. Harter, Katherine P. Reid, Shou Ling Leong, Yuka Kawasawa, Dajiang Liu, John W. Hawley, Keith C. Cheng
Summary: This study focused on a Native American population with high Native American genetic ancestry, aiming to investigate the impact of this ancestry on skin color variation. The results showed that Native American genetic ancestry had the greatest effect on reducing skin pigmentation, while genetic mutations from European and African ancestries had smaller effects. However, the specific genetic variants responsible for light skin in Native American/East Asian populations remain to be identified.
Article
Oncology
Natacha Wurtz Yazdanfard, Lauge Hjorth Mikkelsen, Nille Behrendt, Katrine Fuglsang, Jan Blaakaer, Lisbet Rosenkrantz Holmich, Ligita Paskeviciute Froding, Helga Fibiger Munch-Petersen, Steffen Heegaard
Summary: This study investigated the clinical, pathological, and genetic characteristics of patients with vaginal melanoma in Denmark. The results showed that vaginal melanoma is a rare disease with a poor prognosis, possibly due to vague symptoms and the anatomical location of the disease. Co-mutations in ATRX and TP53 and mutations in TP53 alone were associated with a poor prognosis, suggesting that these genes could be potential targets for future therapy.
GYNECOLOGIC ONCOLOGY
(2022)
Article
Health Care Sciences & Services
Hui-Hui Zhu, Ji-Lei Huang, Chang-Hai Zhou, Ting-Jun Zhu, Jin-Xin Zheng, Mi-Zhen Zhang, Men-Bao Qian, Ying-Dan Chen, Shi-Zhu Li
Summary: A national monitoring was conducted in China from 2016 to 2020 to analyze the prevalence, changing trends, and factors influencing soil-transmitted helminthiasis. The infection rates of soil-transmitted helminths showed a decreasing trend, but there were still areas with high infection rates and exhibited spatiotemporal aggregation.
LANCET REGIONAL HEALTH-WESTERN PACIFIC
(2023)
Editorial Material
Multidisciplinary Sciences
Charles N. Rotimi, Adebowale A. Adeyemo
Summary: Over the past 20 years, the increasing diversity in genomic sequencing has provided valuable insights into our evolutionary history and health status.
Article
Public, Environmental & Occupational Health
Lisa J. Martin, Liza Bronner Murrison, Melinda Butsch Kovacic
Summary: The study recruited 1,020 children aged 3-18 in the Greater Cincinnati Metropolitan region, with 84% non-Hispanic white, 15% non-Hispanic black participants. Participants showed marked demographic and disease burden differences by race, with the cohort broadly used in publications, grants, and patents.
FRONTIERS IN PUBLIC HEALTH
(2021)
Article
Genetics & Heredity
James D. Fife, Christopher A. Cassa
Summary: REGatta is a method that estimates clinical risk of rare missense variants by defining gene regions using pathogenic diagnostic reports and calculating relative risk using over 200,000 exome sequences. This approach shows high concordance with functional assays and better identifies individuals at elevated or reduced risk compared to existing methods.
AMERICAN JOURNAL OF HUMAN GENETICS
(2023)
Article
Fisheries
Muhammed Duman, Noemi Bujan, Soner Altun, Jesus L. Romalde, Izzet Burcin Saticioglu
Summary: This study characterized Vibrio isolates from Turkish fish farms, PubMLST database, and GenBank using multilocus sequence analysis and typing. They found high diversity and genetic interactions within the Vibrio population. 17 new sequence types were discovered, indicating frequent genetic recombination. These findings help understand differences in Vibrio infections in fish and provide insights for effective measures in aquaculture.
Article
Plant Sciences
Pierre de Villemereuil, Oscar E. Gaggiotti, Jerome Goudet
Summary: Common garden experiments are valuable for studying local adaptation without the confounding effect of phenotypic plasticity. The Q(ST) - F-ST comparison framework is commonly used to test the influence of local adaptation on phenotypic divergence between populations. However, the assumptions underlying the equality between Q(ST) and F-ST may not hold in more complex population structures.
JOURNAL OF ECOLOGY
(2022)
Review
Ecology
Maximilian Hirschfeld, Christine Dudgeon, Marcus Sheaves, Adam Barnett
Summary: The study investigates how marine barriers shape genetic connectivity in animals with active dispersal using population genetics and phylogeography literature on elasmobranchs. It finds that barrier types and animals' dispersal potential are important predictors of genetic connectivity in marine populations with active dispersal.
GLOBAL ECOLOGY AND BIOGEOGRAPHY
(2021)
Article
Biochemistry & Molecular Biology
Remi Matthey-Doret
Summary: SimBit is a high-performance population genetics simulator that can simulate various selection, demographic and mating scenarios, track QTLs and model ecological relationships among multiple species. It comes with a convenient R wrapper for project management and outperforms other simulators in most benchmarks.
MOLECULAR ECOLOGY RESOURCES
(2021)
Article
Parasitology
Nicola J. Beesley, Elizabeth Attree, Severo Vazquez-Prieto, Roman Vilas, Esperanza Paniagua, Florencio M. Ubeira, Oscar Jensen, Cesar Pruzzo, Jose D. Alvarez, Jorge Bruno Malandrini, Hugo Solana, Jane E. Hodgkinson
Summary: Population genetic studies on liver fluke populations in four provinces of Argentina revealed significant genetic structuring, with three population clusters identified. Despite the population clustering, there was no deviation from Hardy-Weinberg equilibrium, suggesting random mating within sub-populations. A high clonal diversity of 82% was observed, with 26.6% of parasites displaying identical genotypes, indicating potential clonemate transmission.
INTERNATIONAL JOURNAL FOR PARASITOLOGY
(2021)
Article
Integrative & Complementary Medicine
Chantal Morin, Isabelle Gaboury
Summary: The number of osteopathy empirical studies has significantly increased from 1980 to 2014, showing alignment with practice development and innovation; however, these articles were predominantly published in osteopathic journals targeting a limited, disciplinary-focused readership.
BMC COMPLEMENTARY MEDICINE AND THERAPIES
(2021)