Immunoinflammatory diseases of the central nervous system - the tale of two cytokines
出版年份 2015 全文链接
标题
Immunoinflammatory diseases of the central nervous system - the tale of two cytokines
作者
关键词
-
出版物
BRITISH JOURNAL OF PHARMACOLOGY
Volume 173, Issue 4, Pages 716-728
出版商
Wiley
发表日期
2015-04-27
DOI
10.1111/bph.13175
参考文献
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注意:仅列出部分参考文献,下载原文获取全部文献信息。- From physiology to disease and targeted therapy: interleukin-6 in inflammation and inflammation-associated carcinogenesis
- (2015) Timo Rath et al. ARCHIVES OF TOXICOLOGY
- Interleukin-6 as a Therapeutic Target
- (2015) J.-F. Rossi et al. CLINICAL CANCER RESEARCH
- Aicardi-Goutières Syndrome Is Caused by IFIH1 Mutations
- (2014) Hirotsugu Oda et al. AMERICAN JOURNAL OF HUMAN GENETICS
- Autoimmune Disorders Associated with Gain of Function of the Intracellular Sensor MDA5
- (2014) Masahide Funabiki et al. IMMUNITY
- An RNA-Sequencing Transcriptome and Splicing Database of Glia, Neurons, and Vascular Cells of the Cerebral Cortex
- (2014) Y. Zhang et al. JOURNAL OF NEUROSCIENCE
- Trans-Signaling Is a Dominant Mechanism for the Pathogenic Actions of Interleukin-6 in the Brain
- (2014) I. L. Campbell et al. JOURNAL OF NEUROSCIENCE
- Pathogenesis of neuropsychiatric systemic lupus erythematosus and potential biomarkers
- (2014) Petros Efthimiou et al. Modern Rheumatology
- Clinical improvement in a patient with neuromyelitis optica following therapy with the anti-IL-6 receptor monoclonal antibody tocilizumab
- (2014) Manabu Araki et al. Modern Rheumatology
- Human intracellular ISG15 prevents interferon-α/β over-amplification and auto-inflammation
- (2014) Xianqin Zhang et al. NATURE
- Gain-of-function mutations in IFIH1 cause a spectrum of human disease phenotypes associated with upregulated type I interferon signaling
- (2014) Gillian I Rice et al. NATURE GENETICS
- IL-6 biology: implications for clinical targeting in rheumatic disease
- (2014) Leonard H. Calabrese et al. Nature Reviews Rheumatology
- Efficacy of the anti-IL-6 receptor antibody tocilizumab in neuromyelitis optica: A pilot study
- (2014) M. Araki et al. NEUROLOGY
- The RNA-Editing Enzyme ADAR1 Controls Innate Immune Responses to RNA
- (2014) Niamh M. Mannion et al. Cell Reports
- Central inhibition of interleukin-6 trans-signaling during peripheral infection reduced neuroinflammation and sickness in aged mice
- (2013) Michael D. Burton et al. BRAIN BEHAVIOR AND IMMUNITY
- Cytokines and Chemokines in Neuromyelitis Optica: Pathogenetic and Therapeutic Implications
- (2013) Akiyuki Uzawa et al. BRAIN PATHOLOGY
- The Concise Guide to PHARMACOLOGY 2013/14: Catalytic Receptors
- (2013) Stephen P.H. Alexander et al. BRITISH JOURNAL OF PHARMACOLOGY
- The Concise Guide to PHARMACOLOGY 2013/14: Enzymes
- (2013) Stephen P.H. Alexander et al. BRITISH JOURNAL OF PHARMACOLOGY
- The Concise Guide to PHARMACOLOGY 2013/14: Ion Channels
- (2013) Stephen P.H. Alexander et al. BRITISH JOURNAL OF PHARMACOLOGY
- Cerebrospinal fluid interleukin-6 and glial fibrillary acidic protein levels are increased during initial neuromyelitis optica attacks
- (2013) Akiyuki Uzawa et al. CLINICA CHIMICA ACTA
- Anti-interferon alpha treatment in SLE
- (2013) Kyriakos A. Kirou et al. CLINICAL IMMUNOLOGY
- Type I interferon in neurological disease—The devil from within
- (2013) Markus J. Hofer et al. CYTOKINE & GROWTH FACTOR REVIEWS
- SAMHD1-dependent retroviral control and escape in mice
- (2013) Jan Rehwinkel et al. EMBO JOURNAL
- Neuromyelitis optica: Concept, immunology and treatment
- (2013) Akiyuki Uzawa et al. JOURNAL OF CLINICAL NEUROSCIENCE
- An autoinflammatory neurological disease due to interleukin 6 hypersecretion
- (2013) Ettore Salsano et al. Journal of Neuroinflammation
- The IUPHAR/BPS Guide to PHARMACOLOGY: an expert-driven knowledgebase of drug targets and their ligands
- (2013) Adam J. Pawson et al. NUCLEIC ACIDS RESEARCH
- Type I interferon blockade in systemic lupus erythematosus: where do we stand?
- (2013) B. R. Lauwerys et al. RHEUMATOLOGY
- Interleukin-6: From basic biology to selective blockade of pro-inflammatory activities
- (2013) Jürgen Scheller et al. SEMINARS IN IMMUNOLOGY
- Interleukin 6 Receptor Blockade in Patients With Neuromyelitis Optica Nonresponsive to Anti-CD20 Therapy
- (2013) Ilya Ayzenberg et al. JAMA Neurology
- Altered synaptic transmission in the hippocampus of transgenic mice with enhanced central nervous systems expression of interleukin-6
- (2012) T.E. Nelson et al. BRAIN BEHAVIOR AND IMMUNITY
- Neuromyelitis optica
- (2012) Michael H. Barnett et al. CURRENT OPINION IN NEUROLOGY
- IRF7, a functional factor associates with systemic lupus erythematosus
- (2012) Wang-Dong Xu et al. CYTOKINE
- The interferons and their receptors-distribution and regulation
- (2012) Nicole A de Weerd et al. IMMUNOLOGY AND CELL BIOLOGY
- Interleukin-6, a Major Cytokine in the Central Nervous System
- (2012) María Erta et al. International Journal of Biological Sciences
- Targeting Interleukin-6: All the Way to Treat Autoimmune and Inflammatory Diseases
- (2012) Toshio Tanaka et al. International Journal of Biological Sciences
- The Ex Vivo Production of IL-6 and IL-21 by CD4+ T Cells is Directly Associated with Neurological Disability in Neuromyelitis Optica Patients
- (2012) Ulisses C. Linhares et al. JOURNAL OF CLINICAL IMMUNOLOGY
- Mutations in ADAR1 cause Aicardi-Goutières syndrome associated with a type I interferon signature
- (2012) Gillian I Rice et al. NATURE GENETICS
- Mycobacterial Disease and Impaired IFN- Immunity in Humans with Inherited ISG15 Deficiency
- (2012) D. Bogunovic et al. SCIENCE
- Interleukin-6: from an inflammatory marker to a target for inflammatory diseases
- (2012) Mercedes Rincon TRENDS IN IMMUNOLOGY
- Disease Amelioration With Tocilizumab in a Treatment-Resistant Patient With Neuromyelitis Optica
- (2012) Bernd C. Kieseier et al. JAMA Neurology
- Type I interferonopathies: a novel set of inborn errors of immunity
- (2011) Yanick J. Crow Annals of the New York Academy of Sciences
- Interleukin-6, a mental cytokine
- (2011) Anneleen Spooren et al. BRAIN RESEARCH REVIEWS
- Structural Linkage between Ligand Discrimination and Receptor Activation by Type I Interferons
- (2011) Christoph Thomas et al. CELL
- The inflammasomes in health and disease: from genetics to molecular mechanisms of autoinflammation and beyond
- (2011) Cristina Conforti-Andreoni et al. Cellular & Molecular Immunology
- Aicardi-Goutieres syndrome: from patients to genes and beyond
- (2011) C Chahwan et al. CLINICAL GENETICS
- Inhibition of interleukin-6 trans-signaling in the brain facilitates recovery from lipopolysaccharide-induced sickness behavior
- (2011) Michael D Burton et al. Journal of Neuroinflammation
- HIV-1 restriction factor SAMHD1 is a deoxynucleoside triphosphate triphosphohydrolase
- (2011) David C. Goldstone et al. NATURE
- Competition between ADAR and RNAi pathways for an extensive class of RNA targets
- (2011) Diane Wu et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- Interleukin 6 signaling promotes anti-aquaporin 4 autoantibody production from plasmablasts in neuromyelitis optica
- (2011) Norio Chihara et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Autosomal dominant inheritance of a heterozygous mutation in SAMHD1 causing familial chilblain lupus
- (2010) Jane C. Ravenscroft et al. AMERICAN JOURNAL OF MEDICAL GENETICS PART A
- Association of a functional IRF7 variant with systemic lupus erythematosus
- (2010) Qiong Fu et al. ARTHRITIS AND RHEUMATISM
- Congenital and Perinatal Infections: Throwing New Light with an Old TORCH
- (2010) Anita Shet INDIAN JOURNAL OF PEDIATRICS
- Cytokine and chemokine profiles in neuromyelitis optica: significance of interleukin-6
- (2010) Akiyuki Uzawa et al. Multiple Sclerosis Journal
- Genetic susceptibility to systemic lupus erythematosus in the genomic era
- (2010) Yun Deng et al. Nature Reviews Rheumatology
- Astrocytic damage is far more severe than demyelination in NMO: A clinical CSF biomarker study
- (2010) R. Takano et al. NEUROLOGY
- HIV, Antiretroviral Therapies, and the Brain
- (2010) Kevin J. Liner et al. Current HIV/AIDS Reports
- Pathogenesis of HIV in the Central Nervous System
- (2010) Victor Valcour et al. Current HIV/AIDS Reports
- Transgenic models for cytokine-induced neurological disease
- (2009) Iain L. Campbell et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE
- Interferon-Related Transcriptome Alterations in the Cerebrospinal Fluid Cells of Aicardi-Goutières Patients
- (2009) Alberto Izzotti et al. BRAIN PATHOLOGY
- Aicardi-Goutières syndrome: an important Mendelian mimic of congenital infection
- (2009) Yanick J Crow et al. DEVELOPMENTAL MEDICINE AND CHILD NEUROLOGY
- Site-Specific Production of IL-6 in the Central Nervous System Retargets and Enhances the Inflammatory Response in Experimental Autoimmune Encephalomyelitis
- (2009) A. Quintana et al. JOURNAL OF IMMUNOLOGY
- Context-dependent IL-6 potentiation of interferon- gamma-induced IL-12 secretion and CD40 expression in murine microglia
- (2009) Hsiao-Wen Lin et al. JOURNAL OF NEUROCHEMISTRY
- Mutations involved in Aicardi-Goutières syndrome implicate SAMHD1 as regulator of the innate immune response
- (2009) Gillian I Rice et al. NATURE GENETICS
- Nucleic acid-mediated inflammatory diseases
- (2008) Rachel E. Rigby et al. BIOESSAYS
- Trex1 Prevents Cell-Intrinsic Initiation of Autoimmunity
- (2008) Daniel B. Stetson et al. CELL
- Aicardi–Goutières syndrome (AGS)
- (2008) John B.P. Stephenson EUROPEAN JOURNAL OF PAEDIATRIC NEUROLOGY
- Astrocytes produce interferon-alpha and CXCL10, but not IL-6 or CXCL8, in aicardi-Goutières syndrome
- (2008) Jane T. Van Heteren et al. GLIA
- Nuanced roles of cytokines in three major human brain disorders
- (2008) Lawrence Steinman JOURNAL OF CLINICAL INVESTIGATION
- Promoter polymorphisms in the IRF3 gene confer protection against systemic lupus erythematosus
- (2008) M Akahoshi et al. LUPUS
- ADAR1 is essential for the maintenance of hematopoiesis and suppression of interferon signaling
- (2008) Jochen C Hartner et al. NATURE IMMUNOLOGY
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