Suppression of lethal-7b and miR-125a/b Maturation by Lin28b Enables Maintenance of Stem Cell Properties in Hepatoblasts

IKK  Enforces a LIN28B/TCF7L2 Positive Feedback Loop That Promotes Cancer Cell Stemness and Metastasis

(2015) C. Chen et al.   CANCER RESEARCH

Let-7 and miR-125 cooperate to prime progenitors for astrogliogenesis

(2015) A. Shenoy et al.   EMBO JOURNAL

LIN28 cooperates with WNT signaling to drive invasive intestinal and colorectal adenocarcinoma in mice and humans

(2015) Ho-Chou Tu et al.   GENES & DEVELOPMENT

Lin28b Is Sufficient to Drive Liver Cancer and Necessary for Its Maintenance in Murine Models

(2014) Liem H. Nguyen et al.   CANCER CELL

Genetic variants of the LIN28B gene predict severe radiation pneumonitis in patients with non-small cell lung cancer treated with definitive radiation therapy

(2014) Juyi Wen et al.   EUROPEAN JOURNAL OF CANCER

Decoding the regulatory landscape of medulloblastoma using DNA methylation sequencing

(2014) Volker Hovestadt et al.   NATURE

Lin28: Primal Regulator of Growth and Metabolism in Stem Cells

(2013) Ng Shyh-Chang et al.   Cell Stem Cell

The let-7/LIN-41 Pathway Regulates Reprogramming to Human Induced Pluripotent Stem Cells by Controlling Expression of Prodifferentiation Genes

(2013) Kathleen A. Worringer et al.   Cell Stem Cell

Lin28B Is an Oncofetal Circulating Cancer Stem Cell-Like Marker Associated with Recurrence of Hepatocellular Carcinoma

(2013) Shu-Wen Cheng et al.   PLoS One

Increased Expression of Lin28B Associates with Poor Prognosis in Patients with Oral Squamous Cell Carcinoma

(2013) Tianfu Wu et al.   PLoS One

miR-125b Acts as a Tumor Suppressor in Breast Tumorigenesis via Its Novel Direct Targets ENPEP, CK2-α, CCNJ, and MEGF9

(2013) Andrea Feliciano et al.   PLoS One

SOX2-LIN28/let-7 pathway regulates proliferation and neurogenesis in neural precursors

(2013) F. Cimadamore et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

LIN28 Binds Messenger RNAs at GGAGA Motifs and Regulates Splicing Factor Abundance

(2012) Melissa L. Wilbert et al.   MOLECULAR CELL

LIN28B Promotes Colon Cancer Progression and Metastasis

(2011) C. E. King et al.   CANCER RESEARCH

Lin28A and Lin28B Inhibit let-7 MicroRNA Biogenesis by Distinct Mechanisms

(2011) Elena Piskounova et al.   CELL

MicroRNAs and developmental timing

(2011) Victor Ambros   CURRENT OPINION IN GENETICS & DEVELOPMENT

Use of MicroRNA Let-7 to Control the Replication Specificity of Oncolytic Adenovirus in Hepatocellular Carcinoma Cells

(2011) Huajun Jin et al.   PLoS One

Genome-Wide Studies Reveal That Lin28 Enhances the Translation of Genes Important for Growth and Survival of Human Embryonic Stem Cells

(2011) Shuping Peng et al.   STEM CELLS

Organogenesis and Development of the Liver

(2010) Karim Si-Tayeb et al.   DEVELOPMENTAL CELL

Liver-enriched transcription factors regulate MicroRNA-122 that targets CUTL1 during liver development

(2010) Hui Xu et al.   HEPATOLOGY

MicroRNA-125b suppressesed human liver cancer cell proliferation and metastasis by directly targeting oncogene LIN28B2

(2010) Linhui Liang et al.   HEPATOLOGY

A Yin-Yang balancing act of the lin28/let-7 link in tumorigenesis

(2010) Junfang Ji et al.   JOURNAL OF HEPATOLOGY

MicroRNA-500 as a potential diagnostic marker for hepatocellular carcinoma

(2009) Yusuke Yamamoto et al.   BIOMARKERS

MicroRNAs: Target Recognition and Regulatory Functions

(2009) David P. Bartel   CELL

Raf kinase inhibitory protein suppresses a metastasis signalling cascade involving LIN28 and let-7

(2009) Surabhi Dangi-Garimella et al.   EMBO JOURNAL

MicroRNA-23b cluster microRNAs regulate transforming growth factor-beta/bone morphogenetic protein signaling and liver stem cell differentiation by targeting Smads

(2009) Charles E. Rogler et al.   HEPATOLOGY

Lin28-let7 Modulates Radiosensitivity of Human Cancer Cells With Activation of K-Ras

(2009) Jee-Sun Oh et al.   INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS

Tbx3 controls the fate of hepatic progenitor cells in liver development by suppressing p19ARF expression

(2008) A. Suzuki et al.   DEVELOPMENT

The microRNA-30 Family Is Required for Vertebrate Hepatobiliary Development

(2008) Nicholas J. Hand et al.   GASTROENTEROLOGY