Expression of vaccinia-related kinase 1 (VRK1) accelerates cell proliferation but overcomes cell adhesion mediated drug resistance (CAM-DR) in multiple myeloma

VRK1 interacts with p53 forming a basal complex that is activated by UV-induced DNA damage

(2014) Inmaculada López-Sánchez et al.   FEBS LETTERS

A role for activator of G-protein signaling 3 (AGS3) in multiple myeloma

(2013) Shan Shao et al.   INTERNATIONAL JOURNAL OF HEMATOLOGY

Cell adhesion to fibronectin down-regulates the expression of Spy1 and contributes to drug resistance in multiple myeloma cells

(2013) Min Fei et al.   INTERNATIONAL JOURNAL OF HEMATOLOGY

Adhesion to fibronectin induces p27Kip1 nuclear accumulation through down-regulation of Jab1 and contributes to cell adhesion-mediated drug resistance (CAM-DR) in RPMI 8,226 cells

(2013) Min Fei et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

Nrf2 Pathway Regulates Multidrug-Resistance-Associated Protein 1 in Small Cell Lung Cancer

(2013) Lili Ji et al.   PLoS One

Retinoic Acid/Alpha-Interferon Combination Inhibits Growth and Promotes Apoptosis in Mantle Cell Lymphoma through Akt-Dependent Modulation of Critical Targets

(2012) J. Dal Col et al.   CANCER RESEARCH

Vaccinia-related Kinase 1 (VRK1) Is an Upstream Nucleosomal Kinase Required for the Assembly of 53BP1 Foci in Response to Ionizing Radiation-induced DNA Damage

(2012) Marta Sanz-García et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Overexpression of forkhead box J2 can decrease the migration of breast cancer cells

(2012) Yingying Wang et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Mitogen-activated protein kinase phosphatase 2 regulates histone H3 phosphorylation via interaction with vaccinia-related kinase 1

(2012) Min-Woo Jeong et al.   MOLECULAR BIOLOGY OF THE CELL

Roles of VRK1 as a new player in the control of biological processes required for cell division

(2011) Alberto Valbuena et al.   CELLULAR SIGNALLING

Macro Histone H2A1.2 (MacroH2A1) Protein Suppresses Mitotic Kinase VRK1 during Interphase

(2011) Wanil Kim et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Acquisition of Resistance toward HYD1 Correlates with a Reduction in Cleaved  4 Integrin Expression and a Compromised CAM-DR Phenotype

(2011) M. F. Emmons et al.   MOLECULAR CANCER THERAPEUTICS

Downregulation of VRK1 by p53 in Response to DNA Damage Is Mediated by the Autophagic Pathway

(2011) Alberto Valbuena et al.   PLoS One

Bone marrow microenvironment in myelomagenesis: its potential role in early diagnosis

(2010) Arun Balakumaran et al.   EXPERT REVIEW OF MOLECULAR DIAGNOSTICS

CKS1B Overexpression Implicates Clinical Aggressiveness of Hepatocellular Carcinomas but Not p27Kip1 Protein Turnover: an Independent Prognosticator with Potential p27Kip1-Independent Oncogenic Attributes?

(2009) Ching-Wen Huang et al.   ANNALS OF SURGICAL ONCOLOGY

The Bone Marrow Microenvironment as a Tumor Sanctuary and Contributor to Drug Resistance

(2008) M. B. Meads et al.   CLINICAL CANCER RESEARCH

VRK1 phosphorylates CREB and mediates CCND1 expression

(2008) T.-H. Kang et al.   JOURNAL OF CELL SCIENCE

Plk3 Interacts with and Specifically Phosphorylates VRK1 in Ser342, a Downstream Target in a Pathway That Induces Golgi Fragmentation

(2008) I. Lopez-Sanchez et al.   MOLECULAR AND CELLULAR BIOLOGY

Human VRK1 Is an Early Response Gene and Its Loss Causes a Block in Cell Cycle Progression

(2008) Alberto Valbuena et al.   PLoS One