PDMS Bonding Technologies for Microfluidic Applications: A Review

This review summarizes and compares the available surface treatment and bonding techniques (e.g., corona triggered surface activation, oxygen plasma surface activation, chemical gluing, and mixed techniques) and quality/bond-strength testing methods (e.g., pulling test, shear test, peel test, leakage test) for bonding PDMS (polydimethylsiloxane) with other materials, such as PDMS, glass, silicon, PET (polyethylene terephthalate), PI (polyimide), PMMA (poly(methyl methacrylate)), PVC (polyvinyl chloride), PC (polycarbonate), COC (cyclic olefin copolymer), PS (polystyrene) and PEN (polyethylene naphthalate). The optimized process parameters for the best achievable bond strengths are collected for each substrate, and the advantages and disadvantages of each method are discussed in detail.

Automated summary

This review summarizes and compares various surface treatment and bonding techniques for bonding PDMS with different materials, as well as quality/bond-strength testing methods. The optimized process parameters for achieving the best bond strengths for each substrate are collected, and the advantages and disadvantages of each method are discussed in detail.