Article
Polymer Science
Katharine Burns, Johannes H. H. Potgieter, Sanja Potgieter-Vermaak, Ian D. V. Ingram, Christopher M. M. Liauw
Summary: The lack of a reliable quantitative method for testing plasticizer exudation from PVC formulations hinders the evaluation of novel phthalate-free plasticizers. Two methods, ATR-FTIR and GC-MS, were trialed to improve the ASTM D3291 exudation test. FTIR was found unsuitable due to its insensitivity to small changes in plasticizer distribution, while GC-MS successfully quantified plasticizer exudation that could not be observed visually or by FTIR. Testing multiple aspects of compatibility is important when developing novel plasticizers for use in PVC.
JOURNAL OF APPLIED POLYMER SCIENCE
(2023)
Review
Biochemistry & Molecular Biology
Lucia Vera-Herrera, Daniele Sadutto, Yolanda Pico
Summary: Pesticide residues pose a threat to global human health, and this study summarizes different methods and technologies for assessing human exposure to pesticide residues. It analyzes the direct and indirect ways of estimating pesticide residue exposure and highlights the importance of analytical techniques in this process.
Article
Chemistry, Analytical
Anna Rozanska, Opas Bunkoed, Justyna P. lotka-Wasylka
Summary: A green extraction strategy was developed for the extraction and determination of phthalates from baby diapers. The developed method showed good extraction efficiency and recovery rate, and proved to be a simple, environmentally friendly, and efficient strategy.
MICROCHEMICAL JOURNAL
(2023)
Review
Plant Sciences
Andrzej Patyra, Malgorzata Koltun-Jasion, Oktawia Jakubiak, Anna Karolina Kiss
Summary: Lignans are natural polyphenols with various pharmacological activities, including antimicrobial, anti-inflammatory, hypoglycemic, and cytoprotective effects. They have been found to be associated with a reduced risk of hormone-dependent cancers. Therefore, the extraction, purification, and analysis methods of lignans are crucial in pharmaceutical research.
Review
Biochemical Research Methods
P. S. Amritha, Veena Vinod, P. B. Harathi
Summary: This review provides an overview of various pre-treatment measures and detection methods for PAEs in water and beverages, focusing on the research published in the past 20 years. Multiple sample preparation and analytical methods suitable for reliable determination of PAEs have been identified. However, analyzing PAEs is challenging due to their ubiquitous presence and complexity.
JOURNAL OF CHROMATOGRAPHY A
(2022)
Review
Chemistry, Analytical
Seyedeh Sara Nasrollahi, Negar Sabahi Moosavi, Yadollah Yamini
Summary: Due to concern about health and the environment, green, eco, and environment-friendly practices have been established in different research areas. This has motivated the analytical chemistry community to improve methods that align with the principles of green analytical chemistry. Microextraction techniques, such as sorbent microextraction and liquid-phase microextraction, are of great importance as alternative methods. Parabens, synthetic preservatives widely used in cosmetics, pharmaceuticals, and beverages, are known as endocrine-disrupting chemicals. This review discusses the definition and principles of green chemistry, summarizes the development of green analytical chemistry, and focuses on recent applications for the determination of parabens in different samples.
TRAC-TRENDS IN ANALYTICAL CHEMISTRY
(2023)
Article
Environmental Sciences
Branislav Kolena, Henrieta Hlisnikova, L'ubica Keckesova, Miroslava Sidlovska, Tomas Trnovec, Ida Petrovicova
Summary: This study found that occupational exposure to phthalates may lead to abdominal obesity and be associated with obesity-related metabolic disorders.
Review
Food Science & Technology
Antonio Lama-Munoz, Maria Del Mar Contreras
Summary: Phenolic compounds are valuable food components with potential applications in various industries. Efficient extraction methods and robust analytical tools are crucial for obtaining phenolic-rich extracts and characterizing their chemical structures. This study reviews the extraction techniques and characterisation methods used for phenolic compounds from foods and agri-food by-products.
Article
Chemistry, Analytical
Shivender Singh Saini, Solange Binotto Fagan, Mariana Zancan Tonel
Summary: A novel method for trace analysis of phthalates (PAEs) in water samples, using a self-assembled rotating cigarette filter sorptive extraction (R-CFSE) followed by in-syringe elution with packed cigarette filter, has been established. This method demonstrates high sensitivity, low detection limits, and precision and accuracy within acceptable ranges.
MICROCHEMICAL JOURNAL
(2021)
Article
Environmental Sciences
Jilei Lin, Siying Cheng, Jing Zhang, Liebin Zhao, Shuhua Yuan, Lei Zhang, Yong Yin
Summary: This study aimed to investigate the composite effects of different kinds of phthalates on depression risk in the U.S population. The results showed that urinary mono-isobutyl phthalate (MiBP) and mono-benzyl phthalate (MBzP) were independent risk factors for depression. There was an incrementally higher risk of depression and moderate/severe depression associated with higher levels of phthalates exposure. Non-Hispanic Black participants were more likely to be affected by high levels of MiBP and MBzP exposure than Mexican American participants.
ENVIRONMENTAL RESEARCH
(2023)
Article
Environmental Sciences
Maricel Maffini, Birgit Geueke, Ksenia Groh, Bethanie Carney Almroth, Jane Muncke
Summary: The association between environmental chemical exposures and chronic diseases is concerning, and current reference doses based on male reproductive toxicity may not adequately protect against other health effects. Post-market exposures, epidemiological and clinical data should be systematically reviewed to ensure adequate health protection.
ENVIRONMENTAL HEALTH
(2021)
Article
Environmental Sciences
Wei-Hsiang Chang, Wei-Chun Chou, Alexander Waits, Kai-Wei Liao, Pao-Lin Kuo, Po-Chin Huang
Summary: The study highlights the adverse effects of phthalates on the female reproductive system, especially in women of reproductive age. Cumulative exposure poses a risk to the female reproductive system, suggesting a need for further research in this area.
ENVIRONMENT INTERNATIONAL
(2021)
Review
Chemistry, Analytical
Dyia Syaleyana Md Shukri, Noorfatimah Yahaya, Mazidatulakmam Miskam, Rizana Yusof, Ahmad Husaini Mohamed, Sazlinda Kamaruzaman, Nur Nadhirah Mohamad Zain, Nadhiratul-Farihin Semail
Summary: Misuse and incorrect disposal of fluoroquinolones (FQs) have resulted in environmental pollution and contamination of FQs in food chains. As a result, researchers have been striving to develop innovative and simple techniques for FQs analysis in real samples, with a focus on micro- and macroscale dispersive solid-phase extraction (DSPE). Recent studies have reported the use of DSPE-based techniques for sample preparation and detection of FQs in various matrices. This study summarizes current FQs detection methods using chromatographic and DSPE-based combinations, and evaluates the advantages and analytical performance of DSPE in detecting trace levels of FQs.
MICROCHEMICAL JOURNAL
(2023)
Article
Environmental Sciences
Anika Beyer, Paula Schorgg, Nena Karavasiloglou, Sneha Sarwar, Sabine Rohrmann, Till Barnighausen, Aedin Cassidy, Lisa Connolly, Tilman Kuhn
Summary: Phthalate exposure is associated with increased mortality, emphasizing the need for monitoring its impact on health outcomes.
ENVIRONMENTAL RESEARCH
(2022)
Article
Engineering, Environmental
Chenchen Wang, Panpan Huang, Chunsheng Qiu, Jing Li, Shuailong Hu, Liping Sun, Yaohui Bai, Fu Gao, Chaocan Li, Nannan Liu, Dong Wang, Shaopo Wang
Summary: The study investigated the presence, migration, and health risks of phthalic acid esters (PAEs) in tap water, barreled water, and bottled water in Tianjin, China. Results showed high detection frequencies of PAEs, with DEHP having the highest concentration and positively correlated with storage time and temperature. The study also found that human carcinogenic risks of DEHP may reach the maximum acceptable level under certain conditions.
JOURNAL OF HAZARDOUS MATERIALS
(2021)
Article
Chemistry, Multidisciplinary
Priscilla Porto-Figueira, Jose S. Camara, Ana M. Vigario, Jorge A. M. Pereira
Summary: This study aimed to evaluate the susceptibility of selected bacteria to different low pH conditions and to understand how the type of acid (organic vs inorganic) used for acidification affects their tolerance. The results showed that the tolerance to acidic conditions is dependent on the type of acid used, with bacteria being more susceptible to organic acids than inorganic acids. This has implications for the evaluation of antibacterial extracts, as the susceptibility of bacteria to low pHs obtained using organic or inorganic acids should be taken into consideration.
APPLIED SCIENCES-BASEL
(2023)
Review
Engineering, Chemical
Cristina V. Berenguer, Carolina Andrade, Jorge A. M. Pereira, Rosa Perestrelo, Jose S. Camara
Summary: In the coming years, the world will face challenges from climate change, inefficient use of natural resources, and population growth, which require optimized management of resources and reduction of food waste. The COVID-19 pandemic has also contributed to this issue. The valorization of agri-food waste has emerged as a useful strategy to produce value-added compounds with potential applications in various industries. This review discusses the sustainable challenges, opportunities, trends, and innovations related to the valorization of agri-food waste, highlighting the potential applications in the food, pharmaceutical, and environmental sectors.
Article
Food Science & Technology
Serkan Selli, Rosa Perestrelo, Hasim Kelebek, Onur Sevindik, Fabiano Travaglia, Jean Daniel Coisson, Jose S. Camara, Matteo Bordiga
Summary: The impact of Japanese beetles on the quality indicators of Nebbiolo and Erbaluce grapes, specifically their phenolic and volatile composition, was examined. The study revealed that grapes produced by plants attacked by Japanese beetles had higher levels of phenolic compounds compared to healthy plants. Similarly, the volatile composition of the affected grapes was also higher. The plants responded to the beetle attack by increasing the content of certain volatile compounds.
FOOD RESEARCH INTERNATIONAL
(2023)
Article
Food Science & Technology
Laura Alti-Palacios, Juana Martinez, Jose A. C. Teixeira, Jose S. Camara, Rosa Perestrelo
Summary: This study aimed to investigate the impact of cold pre-fermentative maceration (CPM) treatment on the aromatic and sensory properties of white wines from four grape varieties. A total of 62 aroma compounds were identified using HS-SPME/GC-MS. CPM treatment increased the relative concentration of alcohols, esters, and acids, while the impact on terpenoids varied with grape variety and vintage. Esters made the most significant contribution to the sensory properties, enhancing floral and fruity notes.
Article
Food Science & Technology
Goncalo Jasmins, Rosa Perestrelo, Jean Daniel Coisson, Patricia Sousa, Jose A. Teixeira, Matteo Bordiga, Jose S. Camara
Summary: A study aimed to identify characteristic molecular markers related to the authenticity of Italian fortified wines. The volatilomic fingerprint of popular Italian fortified wines was established using HS-SPME/GCMS. The identified compounds can be used as potential markers for the authenticity and genuineness of these wines, contributing to the identification of fraud or adulteration cases and ensuring quality and safety for consumers.
Article
Chemistry, Analytical
Jose S. Camara, Paulo Fernandes, Nelson Barros, Rosa Perestrelo
Summary: An accurate and selective method combining modified mu-QuEChERS procedure with LC-QqQMS was developed for quantification of PAT in commercial apple juices. This method reduced interference from the matrix and provided a quick analysis within 10 minutes. The method showed good linearity and high recovery for determination of PAT in apple juice.
Article
Chemistry, Analytical
Patricia Sousa, Irene Camacho, Jose S. Camara, Rosa Perestrelo
Summary: Researchers have developed a potential diagnostic method for breast cancer using SDS-PAGE and MALDI-TOF MS, which can distinguish between breast cancer patients and healthy individuals based on peptide ion biosignatures.
Article
Multidisciplinary Sciences
Laura Garcia-Cansino, Maria Angeles Garcia, Maria Luisa Marina, Jose S. Camara, Jorge A. M. Pereira
Summary: Food contamination with pesticides poses risks to consumer safety and undermines food supply chain confidence. This study compares and validates two microextraction techniques for extracting eight pesticides from wastewater samples. Both techniques show good analytical performance with selectivity, linearity, low LODs and LOQs, precision, and high recovery rates. The developed methodologies are simpler, faster, and have a lower environmental impact. The mu SPEed approach is found to be more efficient, easier to perform, and greener. Overall, this study highlights the potential of microextraction techniques for pesticide residue analysis and presents a fast and efficient method for pesticide analysis in wastewater samples.
Review
Multidisciplinary Sciences
Shahida Anusha Siddiqui, Chujun Li, Owusu Fordjour Aidoo, Ito Fernando, Moawiya A. Haddad, Jorge A. M. Pereira, Andrey Blinov, Andrey Golik, Jose S. Camara
Summary: Entomotherapy, the use of insects for medicinal purposes, has a long history and potential as an alternative to traditional pharmaceuticals. 235 insect species have been used in medicine, with a focus on treating digestive and skin disorders. Insects are rich sources of bioactive compounds, demonstrating therapeutic features such as anti-inflammatory, antimicrobial, and antiviral properties. Challenges include regulation barriers and consumer acceptance, but entomotherapy has the potential to revolutionize modern medicine.
Review
Engineering, Chemical
Cristina V. Berenguer, Rosa Perestrelo, Jorge A. M. Pereira, Jose S. Camara
Summary: Sustainable biomass production has great potential for reducing greenhouse gas emissions and providing alternative energy sources. Portugal's abundant residual biomass resources can be transformed into high-value products through thermochemical conversion technologies, improving economic performance, reducing reliance on fossil fuels, and achieving sustainable waste management.
Review
Food Science & Technology
Rosa Perestrelo, Yassine Jaouhari, Teresa Abreu, Mariangie M. Castillo, Fabiano Travaglia, Jorge A. M. Pereira, Jose S. Camara, Matteo Bordiga
Summary: Fortified wines from Mediterranean countries have high alcohol content to increase their shelf-life during long journeys. Marsala, Madeira, Port, and Sherry are famous fortified wines due to their high alcoholic content, sweet taste, and intense aromatic profile. This review provides an overview of the traditional vinification process and regulatory aspects of Italian, Portuguese, and Spanish fortified wines, as well as the volatile organic compounds (VOCs) that contribute to their aroma and the compounds found during oxidative aging.
Article
Oncology
Giulia Riccio, Cristina V. Berenguer, Rosa Perestrelo, Ferdinando Pereira, Pedro Berenguer, Cristina P. Ornelas, Ana Celia Sousa, Joao Aragao Vital, Maria do Carmo Pinto, Jorge A. M. Pereira, Viviana Greco, Jose S. Camara
Summary: Prostate cancer (PCa) is the second most common malignant tumor and the leading cause of oncological death in men. Investigating endogenous volatile organic metabolites (VOMs) has emerged as a non-invasive approach to establish the volatilomic biosignature of PCa. In this study, urine samples from PCa patients and control individuals were analyzed using HS-SPME/GC-MS, revealing 147 different VOMs. Multivariate analysis showed distinct volatomic profiles between the two groups, suggesting potential biomarkers for PCa. However, larger sample sizes are needed to increase the predictability and accuracy of the statistical models developed.